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Q3UX06

- Q3UX06_MOUSE

UniProt

Q3UX06 - Q3UX06_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Parp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. NAD+ ADP-ribosyltransferase activity Source: MGI
    3. NAD binding Source: Ensembl
    4. protein binding Source: MGI
    5. zinc ion binding Source: InterPro

    GO - Biological processi

    1. base-excision repair Source: MGI
    2. cellular response to insulin stimulus Source: Ensembl
    3. cellular response to superoxide Source: MGI
    4. DNA damage response, detection of DNA damage Source: Ensembl
    5. DNA metabolic process Source: MGI
    6. DNA repair Source: MGI
    7. double-strand break repair Source: MGI
    8. positive regulation of SMAD protein import into nucleus Source: Ensembl
    9. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    10. positive regulation of transcription regulatory region DNA binding Source: Ensembl
    11. protein autoprocessing Source: Ensembl
    12. protein poly-ADP-ribosylation Source: Ensembl
    13. regulation of growth rate Source: MGI
    14. signal transduction involved in regulation of gene expression Source: Ensembl
    15. telomere maintenance Source: MGI
    16. transforming growth factor beta receptor signaling pathway Source: Ensembl

    Enzyme and pathway databases

    ReactomeiREACT_220566. Downregulation of SMAD2/3:SMAD4 transcriptional activity.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Parp1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1340806. Parp1.

    Subcellular locationi

    GO - Cellular componenti

    1. nuclear envelope Source: Ensembl
    2. nucleolus Source: MGI
    3. nucleoplasm Source: MGI
    4. nucleus Source: MGI
    5. protein complex Source: MGI
    6. transcription factor complex Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3UX06.

    Expressioni

    Gene expression databases

    ArrayExpressiQ3UX06.
    BgeeiQ3UX06.
    GenevestigatoriQ3UX06.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG088594.
    InParanoidiQ3UX06.

    Family and domain databases

    Gene3Di3.30.1740.10. 2 hits.
    InterProiIPR001510. Znf_PARP.
    [Graphical view]
    PfamiPF00645. zf-PARP. 2 hits.
    [Graphical view]
    PROSITEiPS00347. PARP_ZN_FINGER_1. 2 hits.
    PS50064. PARP_ZN_FINGER_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3UX06-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEASERLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH    50
    WYHFSCFWKV GHSIRQPDVE VDGFSELRWD DQQKVKKTAE AGGVAGKGQD 100
    GSGGKAEKTL GDFLAEYAKS NRSMCKGCLE KIEKGQMRLS KKMVDPEKPQ 150
    LGMIDRWYHP TCFVKKRDEL GFRPEYSASQ LKGFSLLSAE 190
    Length:190
    Mass (Da):21,473
    Last modified:October 11, 2005 - v1
    Checksum:iFC5CB732F65A33F0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei190 – 1901Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK135977 mRNA. Translation: BAE22758.1.
    UniGeneiMm.277779.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK135977 mRNA. Translation: BAE22758.1 .
    UniGenei Mm.277779.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q3UX06.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1340806. Parp1.

    Phylogenomic databases

    HOVERGENi HBG088594.
    InParanoidi Q3UX06.

    Enzyme and pathway databases

    Reactomei REACT_220566. Downregulation of SMAD2/3:SMAD4 transcriptional activity.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3UX06.
    Bgeei Q3UX06.
    Genevestigatori Q3UX06.

    Family and domain databases

    Gene3Di 3.30.1740.10. 2 hits.
    InterProi IPR001510. Znf_PARP.
    [Graphical view ]
    Pfami PF00645. zf-PARP. 2 hits.
    [Graphical view ]
    PROSITEi PS00347. PARP_ZN_FINGER_1. 2 hits.
    PS50064. PARP_ZN_FINGER_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: In vitro fertilized eggsImported.

    Entry informationi

    Entry nameiQ3UX06_MOUSE
    AccessioniPrimary (citable) accession number: Q3UX06
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)