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Q3UX06

- Q3UX06_MOUSE

UniProt

Q3UX06 - Q3UX06_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Parp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. NAD+ ADP-ribosyltransferase activity Source: MGI
  3. NAD binding Source: Ensembl
  4. poly(A) RNA binding Source: Ensembl
  5. zinc ion binding Source: InterPro

GO - Biological processi

  1. base-excision repair Source: MGI
  2. cellular response to insulin stimulus Source: Ensembl
  3. cellular response to superoxide Source: MGI
  4. DNA damage response, detection of DNA damage Source: Ensembl
  5. DNA metabolic process Source: MGI
  6. DNA repair Source: MGI
  7. double-strand break repair Source: MGI
  8. positive regulation of SMAD protein import into nucleus Source: Ensembl
  9. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  10. positive regulation of transcription regulatory region DNA binding Source: Ensembl
  11. protein autoprocessing Source: Ensembl
  12. protein poly-ADP-ribosylation Source: Ensembl
  13. regulation of growth rate Source: MGI
  14. signal transduction involved in regulation of gene expression Source: Ensembl
  15. telomere maintenance Source: MGI
  16. transforming growth factor beta receptor signaling pathway Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_220566. Downregulation of SMAD2/3:SMAD4 transcriptional activity.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Parp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1340806. Parp1.

Subcellular locationi

GO - Cellular componenti

  1. nuclear envelope Source: Ensembl
  2. nucleolus Source: MGI
  3. nucleoplasm Source: MGI
  4. nucleus Source: MGI
  5. protein complex Source: MGI
  6. transcription factor complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3UX06.

Expressioni

Gene expression databases

BgeeiQ3UX06.
ExpressionAtlasiQ3UX06. baseline and differential.
GenevestigatoriQ3UX06.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG088594.

Family and domain databases

Gene3Di3.30.1740.10. 2 hits.
InterProiIPR001510. Znf_PARP.
[Graphical view]
PfamiPF00645. zf-PARP. 2 hits.
[Graphical view]
PROSITEiPS00347. PARP_ZN_FINGER_1. 2 hits.
PS50064. PARP_ZN_FINGER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3UX06-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEASERLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH
60 70 80 90 100
WYHFSCFWKV GHSIRQPDVE VDGFSELRWD DQQKVKKTAE AGGVAGKGQD
110 120 130 140 150
GSGGKAEKTL GDFLAEYAKS NRSMCKGCLE KIEKGQMRLS KKMVDPEKPQ
160 170 180 190
LGMIDRWYHP TCFVKKRDEL GFRPEYSASQ LKGFSLLSAE
Length:190
Mass (Da):21,473
Last modified:October 11, 2005 - v1
Checksum:iFC5CB732F65A33F0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei190 – 1901Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK135977 mRNA. Translation: BAE22758.1.
UniGeneiMm.277779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK135977 mRNA. Translation: BAE22758.1 .
UniGenei Mm.277779.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q3UX06.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1340806. Parp1.

Phylogenomic databases

HOVERGENi HBG088594.

Enzyme and pathway databases

Reactomei REACT_220566. Downregulation of SMAD2/3:SMAD4 transcriptional activity.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q3UX06.
ExpressionAtlasi Q3UX06. baseline and differential.
Genevestigatori Q3UX06.

Family and domain databases

Gene3Di 3.30.1740.10. 2 hits.
InterProi IPR001510. Znf_PARP.
[Graphical view ]
Pfami PF00645. zf-PARP. 2 hits.
[Graphical view ]
PROSITEi PS00347. PARP_ZN_FINGER_1. 2 hits.
PS50064. PARP_ZN_FINGER_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.

Entry informationi

Entry nameiQ3UX06_MOUSE
AccessioniPrimary (citable) accession number: Q3UX06
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)