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Q3UX06 (Q3UX06_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Parp1 MGI 1340806
OrganismMus musculus (Mouse) EMBL BAE22758.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length190 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processDNA damage response, detection of DNA damage

Inferred from electronic annotation. Source: Ensembl

DNA metabolic process

Inferred from mutant phenotype PubMed 11756244PubMed 12707040. Source: MGI

DNA repair

Traceable author statement PubMed 12065591. Source: MGI

base-excision repair

Inferred from mutant phenotype PubMed 11948190. Source: MGI

cellular response to insulin stimulus

Inferred from electronic annotation. Source: Ensembl

double-strand break repair

Inferred from genetic interaction PubMed 21270334. Source: MGI

positive regulation of SMAD protein import into nucleus

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription regulatory region DNA binding

Inferred from electronic annotation. Source: Ensembl

protein autoprocessing

Inferred from electronic annotation. Source: Ensembl

protein poly-ADP-ribosylation

Inferred from electronic annotation. Source: Ensembl

regulation of growth rate

Inferred from mutant phenotype PubMed 12707040. Source: MGI

signal transduction involved in regulation of gene expression

Inferred from electronic annotation. Source: Ensembl

telomere maintenance

Inferred from mutant phenotype PubMed 12707040. Source: MGI

transforming growth factor beta receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentnuclear envelope

Inferred from electronic annotation. Source: Ensembl

nucleolus

Inferred from direct assay PubMed 15615785. Source: MGI

nucleoplasm

Inferred from direct assay PubMed 15615785. Source: MGI

nucleus

Traceable author statement PubMed 12065591. Source: MGI

protein complex

Inferred from direct assay PubMed 19796622. Source: MGI

transcription factor complex

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

NAD binding

Inferred from electronic annotation. Source: Ensembl

NAD+ ADP-ribosyltransferase activity

Inferred from electronic annotation. Source: Ensembl

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue1901 EMBL BAE22758.1

Sequences

Sequence LengthMass (Da)Tools
Q3UX06 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: FC5CB732F65A33F0

FASTA19021,473
        10         20         30         40         50         60 
MAEASERLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV 

        70         80         90        100        110        120 
GHSIRQPDVE VDGFSELRWD DQQKVKKTAE AGGVAGKGQD GSGGKAEKTL GDFLAEYAKS 

       130        140        150        160        170        180 
NRSMCKGCLE KIEKGQMRLS KKMVDPEKPQ LGMIDRWYHP TCFVKKRDEL GFRPEYSASQ 

       190 
LKGFSLLSAE 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE22758.1.
Tissue: In vitro fertilized eggs EMBL BAE22758.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK135977 mRNA. Translation: BAE22758.1.
UniGeneMm.277779.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ3UX06.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1340806. Parp1.

Phylogenomic databases

HOVERGENHBG088594.
InParanoidQ3UX06.

Gene expression databases

ArrayExpressQ3UX06.
BgeeQ3UX06.
GenevestigatorQ3UX06.

Family and domain databases

Gene3D3.30.1740.10. 2 hits.
InterProIPR001510. Znf_PARP.
[Graphical view]
PfamPF00645. zf-PARP. 2 hits.
[Graphical view]
PROSITEPS00347. PARP_ZN_FINGER_1. 2 hits.
PS50064. PARP_ZN_FINGER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ3UX06_MOUSE
AccessionPrimary (citable) accession number: Q3UX06
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)