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Protein
Submitted name:

N-terminally truncated estrogen receptor alpha product-1

Gene

Esr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
N-terminally truncated estrogen receptor alpha product-1Imported
Submitted name:
N-terminally truncated estrogen receptor alpha product-2aImported
Submitted name:
N-terminally truncated estrogen receptor alpha product-2bImported
Submitted name:
N-terminally truncated estrogen receptor alpha product-2cImported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Esr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1352467. Esr1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000019768.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000070070.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 142HOLIInterPro annotationAdd BLAST142
Domaini165 – 208ESR1_CInterPro annotationAdd BLAST44

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG085768.

Family and domain databases

InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR024736. Oestrogen-typ_rcpt_final_C_dom.
PfamiView protein in Pfam
PF12743. ESR1_C. 1 hit.
PF00104. Hormone_recep. 1 hit.
PRINTSiPR00398. STRDHORMONER.
SUPFAMiSSF48508. SSF48508. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UWN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGLVWRSME HPGKLLFAPN LLLDRNQGKC VEGMVEIFDM LLATSSRFRM
60 70 80 90 100
MNLQGEEFVC LKSIILLNSG VYTFLSSTLK SLEEKDHIHR VLDKITDTLI
110 120 130 140 150
HLMAKAGLTL QQQHRRLAQL LLILSHIRHM SNKGMEHLYN MKCKNVVPLY
160 170 180 190 200
DLLLEMLDAH RLHAPASRMG VPPEEPSQTQ LATTSSTSAH SLQTYYIPPE

AEGFPNTI
Length:208
Mass (Da):23,604
Last modified:October 11, 2005 - v1
Checksum:i05643369C28D9BB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136228 mRNA. Translation: BAE22884.1.
AB560757 mRNA. Translation: BAJ65342.1.
AB560758 mRNA. Translation: BAJ65343.1.
AB560759 mRNA. Translation: BAJ65344.1.
AB560760 mRNA. Translation: BAJ65345.1.
UniGeneiMm.463262.
Mm.489063.
Mm.9213.

Genome annotation databases

UCSCiuc011wzo.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136228 mRNA. Translation: BAE22884.1.
AB560757 mRNA. Translation: BAJ65342.1.
AB560758 mRNA. Translation: BAJ65343.1.
AB560759 mRNA. Translation: BAJ65344.1.
AB560760 mRNA. Translation: BAJ65345.1.
UniGeneiMm.463262.
Mm.489063.
Mm.9213.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000070070.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc011wzo.2. mouse.

Organism-specific databases

MGIiMGI:1352467. Esr1.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG085768.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019768.

Family and domain databases

InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR024736. Oestrogen-typ_rcpt_final_C_dom.
PfamiView protein in Pfam
PF12743. ESR1_C. 1 hit.
PF00104. Hormone_recep. 1 hit.
PRINTSiPR00398. STRDHORMONER.
SUPFAMiSSF48508. SSF48508. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UWN0_MOUSE
AccessioniPrimary (citable) accession number: Q3UWN0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 10, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.