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Protein
Submitted name:

N-terminally truncated estrogen receptor alpha product-1

Gene

Esr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
N-terminally truncated estrogen receptor alpha product-1Imported
Submitted name:
N-terminally truncated estrogen receptor alpha product-2aImported
Submitted name:
N-terminally truncated estrogen receptor alpha product-2bImported
Submitted name:
N-terminally truncated estrogen receptor alpha product-2cImported
Gene namesi
Name:Esr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1352467. Esr1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000070070.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 142141HOLIInterPro annotationAdd
BLAST
Domaini165 – 20844ESR1_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG085768.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR024736. Oestrogen-typ_rcpt_final_C_dom.
[Graphical view]
PfamiPF12743. ESR1_C. 1 hit.
PF00104. Hormone_recep. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
SUPFAMiSSF48508. SSF48508. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UWN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGLVWRSME HPGKLLFAPN LLLDRNQGKC VEGMVEIFDM LLATSSRFRM
60 70 80 90 100
MNLQGEEFVC LKSIILLNSG VYTFLSSTLK SLEEKDHIHR VLDKITDTLI
110 120 130 140 150
HLMAKAGLTL QQQHRRLAQL LLILSHIRHM SNKGMEHLYN MKCKNVVPLY
160 170 180 190 200
DLLLEMLDAH RLHAPASRMG VPPEEPSQTQ LATTSSTSAH SLQTYYIPPE

AEGFPNTI
Length:208
Mass (Da):23,604
Last modified:October 11, 2005 - v1
Checksum:i05643369C28D9BB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136228 mRNA. Translation: BAE22884.1.
AB560757 mRNA. Translation: BAJ65342.1.
AB560758 mRNA. Translation: BAJ65343.1.
AB560759 mRNA. Translation: BAJ65344.1.
AB560760 mRNA. Translation: BAJ65345.1.
UniGeneiMm.463262.
Mm.489063.
Mm.9213.

Genome annotation databases

UCSCiuc011wzo.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136228 mRNA. Translation: BAE22884.1.
AB560757 mRNA. Translation: BAJ65342.1.
AB560758 mRNA. Translation: BAJ65343.1.
AB560759 mRNA. Translation: BAJ65344.1.
AB560760 mRNA. Translation: BAJ65345.1.
UniGeneiMm.463262.
Mm.489063.
Mm.9213.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000070070.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc011wzo.2. mouse.

Organism-specific databases

MGIiMGI:1352467. Esr1.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG085768.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR024736. Oestrogen-typ_rcpt_final_C_dom.
[Graphical view]
PfamiPF12743. ESR1_C. 1 hit.
PF00104. Hormone_recep. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
SUPFAMiSSF48508. SSF48508. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  9. "Identification of C-terminally and N-terminally truncated estrogen receptor ? variants in the mouse."
    Ishii H., Shoda Y., Yomogida K., Hamada T., Sakuma Y.
    J. Steroid Biochem. Mol. Biol. 124:38-46(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PituitaryImported.

Entry informationi

Entry nameiQ3UWN0_MOUSE
AccessioniPrimary (citable) accession number: Q3UWN0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 6, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.