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Protein
Submitted name:

Putative uncharacterized protein

Gene

Cacna1f

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Calcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation

Keywords - Biological processi

Calcium transport, Ion transport, Transport

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Cacna1fImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1859639. Cacna1f.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 36HelicalSequence analysisAdd BLAST22
Transmembranei116 – 134HelicalSequence analysisAdd BLAST19
Transmembranei207 – 231HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ3UWK7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000031142.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000111391.

Structurei

3D structure databases

ProteinModelPortaliQ3UWK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini365 – 399Ca_chan_IQInterPro annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili429 – 451Sequence analysisAdd BLAST23

Sequence similaritiesi

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG2301. Eukaryota.
ENOG410XNP6. LUCA.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR031688. CAC1F_C.
IPR027359. Channel_four-helix_dom.
IPR031649. GPHH_dom.
IPR005821. Ion_trans_dom.
IPR014873. VDCC_a1su_IQ.
IPR030157. VDCC_L_a1F.
IPR002077. VDCCAlpha1.
[Graphical view]
PANTHERiPTHR10037:SF184. PTHR10037:SF184. 1 hit.
PfamiPF08763. Ca_chan_IQ. 1 hit.
PF16885. CAC1F_C. 1 hit.
PF16905. GPHH. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00167. CACHANNEL.
SMARTiSM01062. Ca_chan_IQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3UWK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TVALAMQHYE QTAPFNYAMD ILNMVFTGLF TIEMVLKIIA FKPKHYFADA
60 70 80 90 100
WNTFDALIVV GSVVDIAVTE VNSSEDSSRI SITFFRLFRV MRLVKLLSKG
110 120 130 140 150
EGIRTLLWTF IKSFQALPYV ALLIAMIFFI YAVIGMQMFG KVALQDGTQI
160 170 180 190 200
NRNNNFQTFP QAVLLLFRCA TGEAWQEIML ASLPGNRCDP ESDFGPGEEF
210 220 230 240 250
TCGSSFAIVY FISFFMLCAF LIINLFVAVI MDNFDYLTRD WSILGPHHLD
260 270 280 290 300
EFKRIWSEYD PGAKGRIKHL DVVALLRRIQ PPLGFGKLCP HRVACKRLVA
310 320 330 340 350
MNVPLNSDGT VTFNATLFAL VRTSLKIKTE GNLDQANQEL RMVIKKIWKR
360 370 380 390 400
IKQKLLDEVI PPPDEEEVTV GKFYATFLIQ DYFRKFRRRK EKGLLGREAP
410 420 430 440 450
TSTSSALQAG LRSLQDLGPE IRQALTYDTE EEEEEEEAVG QEAEEEEAEN
460 470 480 490 500
NPEPYKDSID SQPQSRWNSR ISVSLPVKEK LPDSLSTGPS DDDGLAPNSR
510 520 530 540 550
QPSVIQAGSQ PHRRSSGVFM FTIPEEGSIQ LKGTQGQDNQ NEEQEVPDWT
560 570 580 590 600
PDLDEQAGTP SNPVLLPPHW SQQHVNGHHV PRRRLLPPTP AGRKPSFTIQ
610 620 630 640 650
CLQRQGSCED LPIPGTYHRG RTSGPSRAQG SWAAPPQKGR LLYAPLLLVE
660 670 680 690 700
ESTVGEGYLG KLGGPLRTFT CLQVPGAHPN PSHRKRGSAD SLVEAVLISE
710 720 730 740 750
GLGLFAQDPR FVALAKQEIA DACHLTLDEM DSAASDLLAQ RTTSLYSDEE
760 770
SILSRFDEED LGDEMACVHA L
Length:771
Mass (Da):86,181
Last modified:October 11, 2005 - v1
Checksum:iA8FF82DE900412FB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136273 mRNA. Translation: BAE22907.1.
UniGeneiMm.289647.

Genome annotation databases

UCSCiuc012hei.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136273 mRNA. Translation: BAE22907.1.
UniGeneiMm.289647.

3D structure databases

ProteinModelPortaliQ3UWK7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000111391.

Proteomic databases

PaxDbiQ3UWK7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc012hei.1. mouse.

Organism-specific databases

MGIiMGI:1859639. Cacna1f.

Phylogenomic databases

eggNOGiKOG2301. Eukaryota.
ENOG410XNP6. LUCA.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031142.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR031688. CAC1F_C.
IPR027359. Channel_four-helix_dom.
IPR031649. GPHH_dom.
IPR005821. Ion_trans_dom.
IPR014873. VDCC_a1su_IQ.
IPR030157. VDCC_L_a1F.
IPR002077. VDCCAlpha1.
[Graphical view]
PANTHERiPTHR10037:SF184. PTHR10037:SF184. 1 hit.
PfamiPF08763. Ca_chan_IQ. 1 hit.
PF16885. CAC1F_C. 1 hit.
PF16905. GPHH. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00167. CACHANNEL.
SMARTiSM01062. Ca_chan_IQ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UWK7_MOUSE
AccessioniPrimary (citable) accession number: Q3UWK7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 5, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.