Arhgap35

Functionⁱ

GO - Biological processⁱ

signal transduction Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Putative uncharacterized proteinImported
Gene namesⁱ	Name:Arhgap35Imported Synonyms:Grlf1Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:1929494. Arhgap35.

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q3UVZ8.
PeptideAtlas More...PeptideAtlasⁱ	Q3UVZ8.
PRIDEⁱ	Q3UVZ8.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q3UVZ8. MM.

Genevisibleⁱ

Q3UVZ8. MM.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	378 – 565	Rho-GAPInterPro annotationAdd BLAST		188

Phylogenomic databases

eggNOGⁱ	KOG4271. Eukaryota. ENOG410XR4E. LUCA.
KEGG Orthology (KO) More...KOⁱ	K05732.

Family and domain databases

InterProⁱ	View protein in InterPro IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00620. RhoGAP. 1 hit.
SMARTⁱ	View protein in SMART SM00324. RhoGAP. 1 hit.
SUPFAMⁱ	SSF48350. SSF48350. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50238. RHOGAP. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q3UVZ8-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
AFLCEVQDII PIQLVALTDG AIDVLDNDLS REQLTEGEEI AQEIDGRFTS 
        60         70         80         90        100
IPCSQPQHKL ELFHPFFKDV VEKKNIIEAT HMYDNVAEAC STTEEVFNSP 
       110        120        130        140        150
RAGSPLCNSN LQDSEEDVEP PSYHLFREDA TLPSLSKDHS KFSMELEGND 
       160        170        180        190        200
GLSFIMSNFE SKLNNKVPPP VKPKPPVHFD ITKDLSYLDQ GHREGQRKSM 
       210        220        230        240        250
SSSPWMPQDG FDPSDYAEPM DAVVKPRNEE ENIYSVPHDS TQGKIITIRN 
       260        270        280        290        300
INKAQSNGSG NGSDSEMDTS SLERGRKVSA VSKPVLYRTR CTRLGRFASY 
       310        320        330        340        350
RTSFSVGSDD ELGPIRKKEE DQASQGYKGD NAVIPYKPDE DPRRRNILRS 
       360        370        380        390        400
LRRNTKKPKP KPRPSITKAT WESNYFGVPL TTVVTPEKPI PIFIERCIEY 
       410        420        430        440        450
IEATGLSTEG IYRVSGNKSE MESLQRQFDQ DHNLDLAEKD FTVNTVAGAM 
       460        470        480        490        500
KSFFSELPDP LVPYSMQIDL VEAHKINDRE QKLHALKEVL KKFPKENHEV 
       510        520        530        540        550
FKYVISHLNK VSHNNKVNLM TSENLSICFW PTLMRPDFSS MDALTATRSY 
       560        570        580        590        600
QTIIELFIQQ CPFFFYNRPI SEPPGAAPGS PSAMAPTVPF LTSTPATSQP 
       610        620 
SPPQSPPPTP QSPMQPLLSS QLQAEHTL

Length:628

Mass (Da):70,570

Last modified:October 11, 2005 - v1

Checksum:ⁱ8B64E2207D13B6E2

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK136766 mRNA. Translation: BAE23121.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_766327.3. NM_172739.4.
UniGeneⁱ	Mm.28646. Mm.400358.

Genome annotation databases

GeneIDⁱ	232906.
KEGGⁱ	mmu:232906.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK136766 mRNA. Translation: BAE23121.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_766327.3. NM_172739.4.
UniGeneⁱ	Mm.28646. Mm.400358.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	Q3UVZ8.
PeptideAtlas More...PeptideAtlasⁱ	Q3UVZ8.
PRIDEⁱ	Q3UVZ8.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	232906.
KEGGⁱ	mmu:232906.

Organism-specific databases

CTDⁱ	2909.
MGIⁱ	MGI:1929494. Arhgap35.

Phylogenomic databases

eggNOGⁱ	KOG4271. Eukaryota. ENOG410XR4E. LUCA.
KEGG Orthology (KO) More...KOⁱ	K05732.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Genevisibleⁱ	Q3UVZ8. MM.

Genevisibleⁱ

Q3UVZ8. MM.

Family and domain databases

InterProⁱ	View protein in InterPro IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00620. RhoGAP. 1 hit.
SMARTⁱ	View protein in SMART SM00324. RhoGAP. 1 hit.
SUPFAMⁱ	SSF48350. SSF48350. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50238. RHOGAP. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q3UVZ8_MOUSE
Accessionⁱ	Q3UVZ8Primary (citable) accession number: Q3UVZ8
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 11, 2005
	Last sequence update:	October 11, 2005
	Last modified:	July 5, 2017
	This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q3UVZ8 (Q3UVZ8_MOUSE)

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Putative uncharacterized protein

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3UVZ8 (Q3UVZ8_MOUSE)

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Putative uncharacterized protein

Arhgap35

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ