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Protein
Submitted name:

NK-3 transcription factor, locus 1 (Drosophila)

Gene

Nkx3-1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi125 – 184HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NK-3 transcription factor, locus 1 (Drosophila)Imported
Gene namesi
Name:Nkx3-1Imported
ORF Names:mCG_4555Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97352 Nkx3-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000022061
ExpressionAtlasiQ3UVH8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3UVH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 183HomeoboxInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili175 – 195Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0842 Eukaryota
ENOG410XR21 LUCA
HOVERGENiHBG006689
KOiK09348
OMAiQTAKQPQ
OrthoDBiEOG091G0RNV

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3UVH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRVAEPREP RVEAGGRSPW AAPPTQSKRL TSFLIQDILR DRAERHGGHS
60 70 80 90 100
GNPQHSPDPR RDSAPEPDKA GGRGVAPEDP PSIRHSPAET PTEPESDAHF
110 120 130 140 150
ETYLLDCEHN PGDLASAPQV TKQPQKRSRA AFSHTQVIEL ERKFSHQKYL
160 170 180 190 200
SAPERAHLAK NLKLTETQVK IWFQNRRYKT KRKQLSEDLG VLEKNSPLSL
210 220 230
PALKDDSLPS TSLVSVYTSY PYYPYLYCLG SWHPSFW
Length:237
Mass (Da):26,824
Last modified:October 11, 2005 - v1
Checksum:i4B074387F3BA1223
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132401 mRNA Translation: AAI32402.1
BC132427 mRNA Translation: AAI32428.1
AK137281 mRNA Translation: BAE23291.1
CH466535 Genomic DNA Translation: EDL35951.1
RefSeqiNP_035051.1, NM_010921.3
UniGeneiMm.3520

Genome annotation databases

GeneIDi18095
KEGGimmu:18095

Similar proteinsi

Entry informationi

Entry nameiQ3UVH8_MOUSE
AccessioniPrimary (citable) accession number: Q3UVH8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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