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Protein

Leucine-rich repeat-containing protein 30

Gene

Lrrc30

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 30
Gene namesi
Name:Lrrc30
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:2685172. Lrrc30.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300Leucine-rich repeat-containing protein 30PRO_0000310987Add
BLAST

Proteomic databases

PRIDEiQ3UV48.

PTM databases

PhosphoSiteiQ3UV48.

Expressioni

Gene expression databases

CleanExiMM_LRRC30.
GenevestigatoriQ3UV48.

Structurei

3D structure databases

ProteinModelPortaliQ3UV48.
SMRiQ3UV48. Positions 31-281.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati47 – 6923LRR 1Add
BLAST
Repeati70 – 9223LRR 2Add
BLAST
Repeati94 – 11522LRR 3Add
BLAST
Repeati116 – 13823LRR 4Add
BLAST
Repeati139 – 16123LRR 5Add
BLAST
Repeati162 – 18423LRR 6Add
BLAST
Repeati186 – 20722LRR 7Add
BLAST
Repeati209 – 23022LRR 8Add
BLAST
Repeati231 – 25323LRR 9Add
BLAST
Repeati261 – 28626LRR 10Add
BLAST

Sequence similaritiesi

Contains 10 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiCOG4886.
HOGENOMiHOG000116557.
HOVERGENiHBG099497.
InParanoidiQ3UV48.
PhylomeDBiQ3UV48.

Family and domain databases

InterProiIPR001611. Leu-rich_rpt.
IPR025875. Leu-rich_rpt_4.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF00560. LRR_1. 1 hit.
PF12799. LRR_4. 1 hit.
PF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 2 hits.
[Graphical view]
PROSITEiPS51450. LRR. 8 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UV48-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGTKQSRASS NDKDPKRLLL GKRQKFSSWD DTLLLGKDPR SLLKRGMRHV
60 70 80 90 100
SFSLVTKGMT DIPDFLWGLL EVQKLNLSHN QLRVLPPEVG RLTRIVVLNL
110 120 130 140 150
CGNCLKSLPR EVSLLQSLKV LFLNMNCLAE VPAELSLCRN LEVLSMSHNC
160 170 180 190 200
LSQLPASFAD LSRLRKLNLS NNYFAHIPLC VFSLKELDFL HVGSNRLKNI
210 220 230 240 250
AESIQCLASL QIFIAESNNI HSFPRSLCLV TSLELLNLNN NDIQTLPDEL
260 270 280 290 300
YLLCRLGRIA WNPMDKGLHI SHNPLSKPLP ELVEGGLEML YSYLKDKKHN
Length:300
Mass (Da):33,931
Last modified:October 11, 2005 - v1
Checksum:i891936A8EE2065F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK137598 mRNA. Translation: BAE23425.1.
CCDSiCCDS28949.1.
RefSeqiNP_001028512.2. NM_001033340.3.
UniGeneiMm.295736.

Genome annotation databases

GeneIDi240131.
KEGGimmu:240131.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK137598 mRNA. Translation: BAE23425.1.
CCDSiCCDS28949.1.
RefSeqiNP_001028512.2. NM_001033340.3.
UniGeneiMm.295736.

3D structure databases

ProteinModelPortaliQ3UV48.
SMRiQ3UV48. Positions 31-281.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ3UV48.

Proteomic databases

PRIDEiQ3UV48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi240131.
KEGGimmu:240131.

Organism-specific databases

CTDi339291.
MGIiMGI:2685172. Lrrc30.

Phylogenomic databases

eggNOGiCOG4886.
HOGENOMiHOG000116557.
HOVERGENiHBG099497.
InParanoidiQ3UV48.
PhylomeDBiQ3UV48.

Miscellaneous databases

NextBioi384476.
PROiQ3UV48.
SOURCEiSearch...

Gene expression databases

CleanExiMM_LRRC30.
GenevestigatoriQ3UV48.

Family and domain databases

InterProiIPR001611. Leu-rich_rpt.
IPR025875. Leu-rich_rpt_4.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF00560. LRR_1. 1 hit.
PF12799. LRR_4. 1 hit.
PF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 2 hits.
[Graphical view]
PROSITEiPS51450. LRR. 8 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Bone.

Entry informationi

Entry nameiLRC30_MOUSE
AccessioniPrimary (citable) accession number: Q3UV48
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 11, 2005
Last modified: January 7, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.