Q3UV48 (LRC30_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Leucine-rich repeat-containing protein 30

Gene names

Name:

Lrrc30

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 10 LRR (leucine-rich) repeats.

Ontologies

Keywords
Domain	Leucine-rich repeat Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Leucine-rich repeat-containing protein 30		PRO_0000310987
Regions
	Repeat	47 – 69	23	LRR 1
	Repeat	70 – 92	23	LRR 2
	Repeat	94 – 115	22	LRR 3
	Repeat	116 – 138	23	LRR 4
	Repeat	139 – 161	23	LRR 5
	Repeat	162 – 184	23	LRR 6
	Repeat	186 – 207	22	LRR 7
	Repeat	209 – 230	22	LRR 8
	Repeat	231 – 253	23	LRR 9
	Repeat	261 – 286	26	LRR 10

Sequences

	Sequence		Length	Mass (Da)
	Q3UV48 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 891936A8EE2065F9	FASTA	300	33,931
	10 20 30 40 50 60 MGTKQSRASS NDKDPKRLLL GKRQKFSSWD DTLLLGKDPR SLLKRGMRHV SFSLVTKGMT 70 80 90 100 110 120 DIPDFLWGLL EVQKLNLSHN QLRVLPPEVG RLTRIVVLNL CGNCLKSLPR EVSLLQSLKV 130 140 150 160 170 180 LFLNMNCLAE VPAELSLCRN LEVLSMSHNC LSQLPASFAD LSRLRKLNLS NNYFAHIPLC 190 200 210 220 230 240 VFSLKELDFL HVGSNRLKNI AESIQCLASL QIFIAESNNI HSFPRSLCLV TSLELLNLNN 250 260 270 280 290 300 NDIQTLPDEL YLLCRLGRIA WNPMDKGLHI SHNPLSKPLP ELVEGGLEML YSYLKDKKHN

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Bone.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK137598 mRNA. Translation: BAE23425.1.
IPI	IPI00342610.
RefSeq	NP_001028512.2. NM_001033340.3.
UniGene	Mm.295736.
3D structure databases
ProteinModelPortal	Q3UV48.
SMR	Q3UV48. Positions 10-274.
ModBase	Search...
PTM databases
PhosphoSite	Q3UV48.
Proteomic databases
PRIDE	Q3UV48.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	240131.
KEGG	mmu:240131.
Organism-specific databases
CTD	339291.
MGI	MGI:2685172. Lrrc30.
Phylogenomic databases
eggNOG	COG4886.
HOGENOM	HOG000116557.
HOVERGEN	HBG099497.
InParanoid	Q3UV48.
OrthoDB	EOG48WC2K.
Gene expression databases
CleanEx	MM_LRRC30.
Genevestigator	Q3UV48.
Family and domain databases
InterPro	IPR001611. Leu-rich_rpt. IPR025875. Leu-rich_rpt_4. IPR003591. Leu-rich_rpt_typical-subtyp. [Graphical view]
Pfam	PF00560. LRR_1. 1 hit. PF12799. LRR_4. 1 hit. [Graphical view]
SMART	SM00369. LRR_TYP. 2 hits. [Graphical view]
PROSITE	PS51450. LRR. 8 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	384476.
SOURCE	Search...

Entry information

Entry name

LRC30_MOUSE

Accession

Primary (citable) accession number: Q3UV48

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	October 11, 2005
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program