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Q3UTZ0

- Q3UTZ0_MOUSE

UniProt

Q3UTZ0 - Q3UTZ0_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Fzd6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. PDZ domain binding Source: RefGenome
    2. protein binding Source: MGI
    3. Wnt-activated receptor activity Source: RefGenome
    4. Wnt-protein binding Source: MGI

    GO - Biological processi

    1. angiogenesis Source: RefGenome
    2. axonogenesis Source: RefGenome
    3. canonical Wnt signaling pathway Source: RefGenome
    4. cell proliferation in midbrain Source: MGI
    5. embryonic nail plate morphogenesis Source: MGI
    6. establishment of planar polarity Source: MGI
    7. gonad development Source: RefGenome
    8. G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Source: RefGenome
    9. hair follicle development Source: MGI
    10. inner ear morphogenesis Source: MGI
    11. midbrain development Source: MGI
    12. negative regulation of canonical Wnt signaling pathway Source: Ensembl
    13. negative regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
    14. neural tube closure Source: MGI
    15. platelet activation Source: MGI
    16. regulation of transcription from RNA polymerase II promoter Source: RefGenome
    17. Wnt signaling pathway, planar cell polarity pathway Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Fzd6Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:108474. Fzd6.

    Subcellular locationi

    GO - Cellular componenti

    1. apical part of cell Source: MGI
    2. apicolateral plasma membrane Source: MGI
    3. cytoplasm Source: RefGenome
    4. neuron projection membrane Source: RefGenome

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3UTZ0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ3UTZ0.
    BgeeiQ3UTZ0.
    GenevestigatoriQ3UTZ0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3UTZ0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG006977.
    InParanoidiQ3UTZ0.
    KOiK02376.

    Family and domain databases

    InterProiIPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR026543. FZD6.
    IPR017981. GPCR_2-like.
    [Graphical view]
    PANTHERiPTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    PfamiPF01534. Frizzled. 1 hit.
    [Graphical view]
    PRINTSiPR00489. FRIZZLED.
    PROSITEiPS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3UTZ0-1 [UniParc]FASTAAdd to Basket

    « Hide

    AVWFHAVAWG APGFLTVMLL AMNKVEGDNI SGVCFVGLYD LDASRYFVLL    50
    PLCLCVFVGL SLLLAGIISL NHVRQVIQHD GRNQEKLKKF MIRIGVFSGL 100
    YLVPLVTLLG CYVYELVNRI TWEMTWFSDH CHQYRIPCPY QANPKARPEL 150
    ALFMIKYLMT LIVGISAVFW VGSKKTCTEW AGFFKRNRKR DPISESRRVL 200
    QESCEFFLKH NSKVKHKKKH GAPGPHRLKV ISKSMGTSTG ATTNHGTSAM 250
    AIADHDYLGQ ETSTEVHTSP EASVKEGRAD RANTPSAKDR DCGESAGPSS 300
    KLSGNRNGRE SRAGGLKERS NGSEGAPSEG RVSPKSSVPE TGLIDCSTSQ 350
    AASSPEPTSL KGSTSLPVHS ASRARKEQGA GSHSDA 386
    Length:386
    Mass (Da):42,124
    Last modified:October 11, 2005 - v1
    Checksum:i038413B4EDC0B2FB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK138964 mRNA. Translation: BAE23839.1.
    RefSeqiNP_001155966.1. NM_001162494.1.
    NP_032082.3. NM_008056.3.
    UniGeneiMm.4769.

    Genome annotation databases

    GeneIDi14368.
    KEGGimmu:14368.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK138964 mRNA. Translation: BAE23839.1 .
    RefSeqi NP_001155966.1. NM_001162494.1.
    NP_032082.3. NM_008056.3.
    UniGenei Mm.4769.

    3D structure databases

    ProteinModelPortali Q3UTZ0.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q3UTZ0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 14368.
    KEGGi mmu:14368.

    Organism-specific databases

    CTDi 8323.
    MGIi MGI:108474. Fzd6.

    Phylogenomic databases

    HOVERGENi HBG006977.
    InParanoidi Q3UTZ0.
    KOi K02376.

    Miscellaneous databases

    ChiTaRSi FZD6. mouse.
    NextBioi 285845.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3UTZ0.
    Bgeei Q3UTZ0.
    Genevestigatori Q3UTZ0.

    Family and domain databases

    InterProi IPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR026543. FZD6.
    IPR017981. GPCR_2-like.
    [Graphical view ]
    PANTHERi PTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    Pfami PF01534. Frizzled. 1 hit.
    [Graphical view ]
    PRINTSi PR00489. FRIZZLED.
    PROSITEi PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.

    Entry informationi

    Entry nameiQ3UTZ0_MOUSE
    AccessioniPrimary (citable) accession number: Q3UTZ0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)