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Protein
Submitted name:

Putative uncharacterized protein

Gene

Fzd6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • canonical Wnt signaling pathway Source: GO_Central
  • cell proliferation in midbrain Source: MGI
  • embryonic nail plate morphogenesis Source: MGI
  • establishment of planar polarity Source: MGI
  • G-protein coupled receptor signaling pathway Source: GOC
  • hair follicle development Source: MGI
  • inner ear morphogenesis Source: MGI
  • midbrain development Source: MGI
  • negative regulation of canonical Wnt signaling pathway Source: MGI
  • negative regulation of sequence-specific DNA binding transcription factor activity Source: MGI
  • neural tube closure Source: MGI
  • non-canonical Wnt signaling pathway Source: MGI
  • platelet activation Source: MGI
  • Wnt signaling pathway, planar cell polarity pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Fzd6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:108474. Fzd6.

Subcellular locationi

GO - Cellular componenti

  • apical part of cell Source: MGI
  • apicolateral plasma membrane Source: MGI
  • integral component of membrane Source: GO_Central
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3UTZ0.

Expressioni

Gene expression databases

BgeeiQ3UTZ0.
ExpressionAtlasiQ3UTZ0. baseline and differential.
GenevisibleiQ3UTZ0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022906.

Structurei

3D structure databases

ProteinModelPortaliQ3UTZ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG006977.
KOiK02376.

Family and domain databases

InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
PROSITEiPS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3UTZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AVWFHAVAWG APGFLTVMLL AMNKVEGDNI SGVCFVGLYD LDASRYFVLL
60 70 80 90 100
PLCLCVFVGL SLLLAGIISL NHVRQVIQHD GRNQEKLKKF MIRIGVFSGL
110 120 130 140 150
YLVPLVTLLG CYVYELVNRI TWEMTWFSDH CHQYRIPCPY QANPKARPEL
160 170 180 190 200
ALFMIKYLMT LIVGISAVFW VGSKKTCTEW AGFFKRNRKR DPISESRRVL
210 220 230 240 250
QESCEFFLKH NSKVKHKKKH GAPGPHRLKV ISKSMGTSTG ATTNHGTSAM
260 270 280 290 300
AIADHDYLGQ ETSTEVHTSP EASVKEGRAD RANTPSAKDR DCGESAGPSS
310 320 330 340 350
KLSGNRNGRE SRAGGLKERS NGSEGAPSEG RVSPKSSVPE TGLIDCSTSQ
360 370 380
AASSPEPTSL KGSTSLPVHS ASRARKEQGA GSHSDA
Length:386
Mass (Da):42,124
Last modified:October 11, 2005 - v1
Checksum:i038413B4EDC0B2FB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK138964 mRNA. Translation: BAE23839.1.
RefSeqiNP_001155966.1. NM_001162494.1.
NP_032082.3. NM_008056.3.
UniGeneiMm.4769.

Genome annotation databases

GeneIDi14368.
KEGGimmu:14368.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK138964 mRNA. Translation: BAE23839.1.
RefSeqiNP_001155966.1. NM_001162494.1.
NP_032082.3. NM_008056.3.
UniGeneiMm.4769.

3D structure databases

ProteinModelPortaliQ3UTZ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022906.

Proteomic databases

PRIDEiQ3UTZ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi14368.
KEGGimmu:14368.

Organism-specific databases

CTDi8323.
MGIiMGI:108474. Fzd6.

Phylogenomic databases

HOVERGENiHBG006977.
KOiK02376.

Miscellaneous databases

ChiTaRSiFzd6. mouse.
NextBioi285845.
SOURCEiSearch...

Gene expression databases

BgeeiQ3UTZ0.
ExpressionAtlasiQ3UTZ0. baseline and differential.
GenevisibleiQ3UTZ0. MM.

Family and domain databases

InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
PROSITEiPS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.

Entry informationi

Entry nameiQ3UTZ0_MOUSE
AccessioniPrimary (citable) accession number: Q3UTZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 24, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.