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Q3UTZ0

- Q3UTZ0_MOUSE

UniProt

Q3UTZ0 - Q3UTZ0_MOUSE

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Protein
Submitted name: Putative uncharacterized protein
Gene
Fzd6
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. PDZ domain binding Source: RefGenome
  3. Wnt-activated receptor activity Source: RefGenome
  4. Wnt-protein binding Source: MGI
  5. protein binding Source: MGI

GO - Biological processi

  1. G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Source: RefGenome
  2. Wnt signaling pathway, planar cell polarity pathway Source: MGI
  3. angiogenesis Source: RefGenome
  4. axonogenesis Source: RefGenome
  5. canonical Wnt signaling pathway Source: RefGenome
  6. cell proliferation in midbrain Source: MGI
  7. embryonic nail plate morphogenesis Source: MGI
  8. establishment of planar polarity Source: MGI
  9. gonad development Source: RefGenome
  10. hair follicle development Source: MGI
  11. inner ear morphogenesis Source: MGI
  12. midbrain development Source: MGI
  13. negative regulation of canonical Wnt signaling pathway Source: Ensembl
  14. negative regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
  15. neural tube closure Source: MGI
  16. platelet activation Source: MGI
  17. regulation of transcription from RNA polymerase II promoter Source: RefGenome
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Fzd6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:108474. Fzd6.

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: MGI
  2. apicolateral plasma membrane Source: MGI
  3. cytoplasm Source: RefGenome
  4. integral component of membrane Source: UniProtKB-KW
  5. neuron projection membrane Source: RefGenome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3UTZ0.

Expressioni

Gene expression databases

ArrayExpressiQ3UTZ0.
BgeeiQ3UTZ0.
GenevestigatoriQ3UTZ0.

Structurei

3D structure databases

ProteinModelPortaliQ3UTZ0.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG006977.
InParanoidiQ3UTZ0.
KOiK02376.

Family and domain databases

InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
PROSITEiPS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3UTZ0-1 [UniParc]FASTAAdd to Basket

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AVWFHAVAWG APGFLTVMLL AMNKVEGDNI SGVCFVGLYD LDASRYFVLL    50
PLCLCVFVGL SLLLAGIISL NHVRQVIQHD GRNQEKLKKF MIRIGVFSGL 100
YLVPLVTLLG CYVYELVNRI TWEMTWFSDH CHQYRIPCPY QANPKARPEL 150
ALFMIKYLMT LIVGISAVFW VGSKKTCTEW AGFFKRNRKR DPISESRRVL 200
QESCEFFLKH NSKVKHKKKH GAPGPHRLKV ISKSMGTSTG ATTNHGTSAM 250
AIADHDYLGQ ETSTEVHTSP EASVKEGRAD RANTPSAKDR DCGESAGPSS 300
KLSGNRNGRE SRAGGLKERS NGSEGAPSEG RVSPKSSVPE TGLIDCSTSQ 350
AASSPEPTSL KGSTSLPVHS ASRARKEQGA GSHSDA 386
Length:386
Mass (Da):42,124
Last modified:October 11, 2005 - v1
Checksum:i038413B4EDC0B2FB
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK138964 mRNA. Translation: BAE23839.1.
RefSeqiNP_001155966.1. NM_001162494.1.
NP_032082.3. NM_008056.3.
UniGeneiMm.4769.

Genome annotation databases

GeneIDi14368.
KEGGimmu:14368.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK138964 mRNA. Translation: BAE23839.1 .
RefSeqi NP_001155966.1. NM_001162494.1.
NP_032082.3. NM_008056.3.
UniGenei Mm.4769.

3D structure databases

ProteinModelPortali Q3UTZ0.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q3UTZ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 14368.
KEGGi mmu:14368.

Organism-specific databases

CTDi 8323.
MGIi MGI:108474. Fzd6.

Phylogenomic databases

HOVERGENi HBG006977.
InParanoidi Q3UTZ0.
KOi K02376.

Miscellaneous databases

ChiTaRSi FZD6. mouse.
NextBioi 285845.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q3UTZ0.
Bgeei Q3UTZ0.
Genevestigatori Q3UTZ0.

Family and domain databases

InterProi IPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view ]
PANTHERi PTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
Pfami PF01534. Frizzled. 1 hit.
[Graphical view ]
PRINTSi PR00489. FRIZZLED.
PROSITEi PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.

Entry informationi

Entry nameiQ3UTZ0_MOUSE
AccessioniPrimary (citable) accession number: Q3UTZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 9, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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