Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q3UTR7 (Q3UTR7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length482 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the serpin family. RuleBase RU000411

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processERK1 and ERK2 cascade

Inferred from electronic annotation. Source: Ensembl

G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

activation of NF-kappaB-inducing kinase activity

Inferred from direct assay PubMed 19404405. Source: MGI

activation of phospholipase C activity

Inferred from electronic annotation. Source: Ensembl

aging

Inferred from electronic annotation. Source: Ensembl

angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure

Inferred from direct assay PubMed 10425188. Source: MGI

angiotensin-mediated drinking behavior

Inferred from electronic annotation. Source: Ensembl

artery smooth muscle contraction

Inferred from electronic annotation. Source: Ensembl

astrocyte activation

Inferred from mutant phenotype PubMed 9734405. Source: MGI

blood vessel development

Inferred from mutant phenotype PubMed 8675666PubMed 9466969. Source: MGI

brain renin-angiotensin system

Inferred from direct assay PubMed 15499027PubMed 9878677. Source: MGI

branching involved in ureteric bud morphogenesis

Inferred from direct assay PubMed 12657564. Source: MGI

catenin import into nucleus

Inferred from electronic annotation. Source: Ensembl

cell growth involved in cardiac muscle cell development

Inferred from electronic annotation. Source: Ensembl

cell-matrix adhesion

Inferred from mutant phenotype PubMed 9734405. Source: MGI

cellular response to mechanical stimulus

Inferred from electronic annotation. Source: Ensembl

cellular sodium ion homeostasis

Inferred from electronic annotation. Source: Ensembl

cytokine secretion

Inferred from electronic annotation. Source: Ensembl

drinking behavior

Inferred from mutant phenotype PubMed 9852267. Source: MGI

establishment of blood-nerve barrier

Inferred from mutant phenotype PubMed 9734405. Source: MGI

excretion

Inferred from mutant phenotype PubMed 9557921. Source: MGI

extracellular matrix organization

Inferred from mutant phenotype PubMed 9734405. Source: MGI

fibroblast proliferation

Inferred from electronic annotation. Source: Ensembl

hormone metabolic process

Inferred from mutant phenotype PubMed 12660889. Source: MGI

kidney development

Inferred from mutant phenotype PubMed 8675666PubMed 9466969. Source: MGI

negative regulation of angiogenesis

Inferred from electronic annotation. Source: Ensembl

negative regulation of cell growth

Inferred from electronic annotation. Source: Ensembl

negative regulation of cell proliferation

Inferred from mutant phenotype PubMed 10318840PubMed 11606482PubMed 8675666. Source: MGI

negative regulation of endopeptidase activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

negative regulation of neuron apoptotic process

Inferred from mutant phenotype PubMed 9310306. Source: MGI

negative regulation of neurotrophin TRK receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

negative regulation of tissue remodeling

Inferred from electronic annotation. Source: Ensembl

ovarian follicle rupture

Inferred from mutant phenotype PubMed 11384650. Source: MGI

peristalsis

Inferred from mutant phenotype PubMed 9788961. Source: MGI

positive regulation of MAPK cascade

Inferred from mutant phenotype PubMed 9196031. Source: MGI

positive regulation of activation of JAK2 kinase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of branching involved in ureteric bud morphogenesis

Inferred from electronic annotation. Source: Ensembl

positive regulation of cardiac muscle hypertrophy

Inferred from electronic annotation. Source: Ensembl

positive regulation of cholesterol esterification

Inferred from electronic annotation. Source: Ensembl

positive regulation of endothelial cell migration

Inferred from electronic annotation. Source: Ensembl

positive regulation of epidermal growth factor receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of extracellular matrix constituent secretion

Inferred from electronic annotation. Source: Ensembl

positive regulation of extrinsic apoptotic signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of fatty acid biosynthetic process

Inferred from mutant phenotype PubMed 11606482. Source: MGI

positive regulation of fibroblast proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of gene expression

Inferred from direct assay PubMed 19404405. Source: MGI

positive regulation of multicellular organism growth

Inferred from mutant phenotype PubMed 12660889. Source: MGI

positive regulation of organ growth

Inferred from direct assay PubMed 16374517. Source: MGI

positive regulation of phosphatidylinositol 3-kinase signaling

Inferred from electronic annotation. Source: Ensembl

positive regulation of protein tyrosine kinase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of renal sodium excretion

Inferred from electronic annotation. Source: Ensembl

positive regulation of superoxide anion generation

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription, DNA-templated

Inferred from electronic annotation. Source: Ensembl

regulation of apoptotic process

Inferred from direct assay PubMed 19404405. Source: MGI

regulation of blood pressure

Inferred from mutant phenotype PubMed 9557921. Source: MGI

regulation of calcium ion transport

Inferred from electronic annotation. Source: Ensembl

regulation of gene expression

Inferred from direct assay PubMed 16585392. Source: MGI

regulation of inflammatory response

Inferred from direct assay PubMed 19404405. Source: MGI

regulation of long-term neuronal synaptic plasticity

Inferred from electronic annotation. Source: Ensembl

regulation of norepinephrine secretion

Inferred from electronic annotation. Source: Ensembl

regulation of proteolysis

Inferred from Biological aspect of Ancestor. Source: RefGenome

regulation of renal output by angiotensin

Inferred from mutant phenotype PubMed 11606482PubMed 9507198PubMed 9852267. Source: MGI

regulation of systemic arterial blood pressure by circulatory renin-angiotensin

Inferred from mutant phenotype PubMed 10076178PubMed 11606482PubMed 12574102PubMed 7989296PubMed 9466969PubMed 9507198PubMed 9852267. Source: MGI

renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure

Inferred from mutant phenotype PubMed 11606482. Source: MGI

renin-angiotensin regulation of aldosterone production

Inferred from mutant phenotype PubMed 10076178PubMed 9852267. Source: MGI

response to cold

Inferred from mutant phenotype PubMed 12574102. Source: MGI

response to muscle activity involved in regulation of muscle adaptation

Inferred from electronic annotation. Source: Ensembl

response to salt stress

Inferred from mutant phenotype PubMed 9557921. Source: MGI

smooth muscle cell differentiation

Inferred from direct assay PubMed 9788961. Source: MGI

smooth muscle cell proliferation

Inferred from direct assay PubMed 9788961. Source: MGI

stress-activated MAPK cascade

Inferred from electronic annotation. Source: Ensembl

uterine smooth muscle contraction

Inferred from electronic annotation. Source: Ensembl

vasodilation

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentextracellular space

Inferred from direct assay PubMed 10425188PubMed 11606482PubMed 7989296. Source: MGI

   Molecular_functionacetyltransferase activator activity

Inferred from electronic annotation. Source: Ensembl

serine-type endopeptidase inhibitor activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

type 1 angiotensin receptor binding

Inferred from direct assay PubMed 9878677. Source: MGI

type 2 angiotensin receptor binding

Inferred from physical interaction PubMed 9878677. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q3UTR7 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: DC4633B4020178C9

FASTA48252,670
        10         20         30         40         50         60 
MHRSEMTPTG AGLKATIFCI LTWVSLTAGD RVYIHPFHLL YHNKSTCAQL ENPSVETLPE 

        70         80         90        100        110        120 
STFEPVPIQA KTSPVNEKTL HDQLVLAAEK LEDEDRKRAA QVAMIANFVG FRMYKMLNEA 

       130        140        150        160        170        180 
GSGASGAILS PPALFGTLVS FYLGSLDPTA SQLQTLLDVP VKEGDCTSRL DGHKVLAALR 

       190        200        210        220        230        240 
AIQGLLVTQG GSSSQTPLLQ SIVVGLFTAP GFRLKHSFVQ SLALFTPALF PRSLDLSTDP 

       250        260        270        280        290        300 
VLATEKINRF IKAVTGWKMN LPLEGVSTDS TLLFNTYVHF QGTMRGFSQL PGVHEFWVDN 

       310        320        330        340        350        360 
SISVSVPMIS GTGNFQHWSD TQNNFSVTCV PLGERATLLL IQPHCTSDLD RVEALIFRND 

       370        380        390        400        410        420 
LLTWIENPPP RAIRLTLPQL EIRGSYNLQD LLAEDKLPTL LGAEANLNNI GDTNPRVGEV 

       430        440        450        460        470        480 
LNSILLELKA GEEEQPTTSV QQPGSPEALD VTLSSPFLFA IYEQDSGTLH FLGRVNNPQS 


VV 

« Hide

References

« Hide 'large scale' references
[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE23913.1.
Tissue: Cerebellum EMBL BAE23913.1.
[9]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000066488.
[10]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000066488.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC126930 Genomic DNA. No translation available.
AK139179 mRNA. Translation: BAE23913.1.
RefSeqNP_031454.3. NM_007428.3.
UniGeneMm.301626.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000066488.

Protein family/group databases

MEROPSI04.953.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000063278; ENSMUSP00000066488; ENSMUSG00000031980.
GeneID11606.
KEGGmmu:11606.
UCSCuc009nxe.1. mouse.

Organism-specific databases

CTD183.
MGIMGI:87963. Agt.

Phylogenomic databases

GeneTreeENSGT00750000117773.
HOGENOMHOG000033941.
HOVERGENHBG004233.
InParanoidQ3UTR7.
KOK09821.
OMARFMQAVT.
OrthoDBEOG7QK0BN.
TreeFamTF343201.

Gene expression databases

GenevestigatorQ3UTR7.

Family and domain databases

InterProIPR000227. Angiotensinogen.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
PRINTSPR00654. ANGIOTENSNGN.
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. SSF56574. 1 hit.
ProtoNetSearch...

Other

NextBio279140.
SOURCESearch...

Entry information

Entry nameQ3UTR7_MOUSE
AccessionPrimary (citable) accession number: Q3UTR7
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)