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Q3USS1 (Q3USS1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Bmpr1b MGI 107191
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate. SAAS SAAS000333

Sequence similarities

Belongs to the protein kinase superfamily. RuleBase RU000305

Contains protein kinase domain. SAAS SAAS000333

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix SAAS SAAS000333
   LigandATP-binding RuleBase RU000304 SAAS SAAS000333
Nucleotide-binding
   Molecular functionKinase
Receptor SAAS SAAS000333
Serine/threonine-protein kinase SAAS SAAS000333 RuleBase RU000305
Transferase
Gene Ontology (GO)
   Biological_processBMP signaling pathway

Inferred from mutant phenotype PubMed 11376112. Source: MGI

camera-type eye development

Inferred from genetic interaction PubMed 15673568. Source: MGI

cartilage condensation

Inferred from mutant phenotype PubMed 10631181. Source: MGI

cell differentiation

Inferred from mutant phenotype PubMed 12117821. Source: MGI

chondrocyte differentiation

Inferred from genetic interaction PubMed 18363966. Source: MGI

dorsal/ventral pattern formation

Inferred from genetic interaction PubMed 15673568. Source: MGI

eye development

Inferred from mutant phenotype PubMed 12117821. Source: MGI

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Inferred from genetic interaction PubMed 18363966. Source: MGI

retina development in camera-type eye

Inferred from mutant phenotype PubMed 12654290. Source: MGI

retinal ganglion cell axon guidance

Inferred from mutant phenotype PubMed 12654290. Source: MGI

transforming growth factor beta receptor signaling pathway

Traceable author statement PubMed 10631181. Source: MGI

transmembrane receptor protein serine/threonine kinase signaling pathway

Inferred from genetic interaction PubMed 18363966. Source: MGI

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

transforming growth factor beta receptor activity, type I

Inferred from mutant phenotype PubMed 11376112. Source: MGI

transforming growth factor beta-activated receptor activity

Traceable author statement PubMed 10631181. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q3USS1 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 5F360D59A5B8F6E8

FASTA49155,894
        10         20         30         40         50         60 
MWAPRRRMER VQPPPLGPRS YVVNATTTVR KTQSTISADG YCFTMIEEDD SGMPVVTSGC 

        70         80         90        100        110        120 
LGLEGSDFQC RDTPIPHQRR SIECCTERNE CNKDLHPTLP PLKDRDFVDG PIHHKALLIS 

       130        140        150        160        170        180 
VTVCSLLLVL IILFCYFRYK RQEARPRYSI GLEQDETYIP PGESLRDLIE QSQSSGSGSG 

       190        200        210        220        230        240 
LPLLVQRTIA KQIQMVKQIG KGRYGEVWMG KWRGEKVAVK VFFTTEEASW FRETEIYQTV 

       250        260        270        280        290        300 
LMRHENILGF IAADIKGTGS WTQLYLITDY HENGSLYDYL KSTTLDAKSM LKLAYSSVSG 

       310        320        330        340        350        360 
LCHLHTEIFS TQGKPAIAHR DLKSKNILVK KNGTCCIADL GLAVKFISDT NEVDIPPNTR 

       370        380        390        400        410        420 
VGTKRYMPPE VLDESLNRNH FQSYIMADMY SFGLILWEIA RRCVSGGIVE EYQLPYHDLV 

       430        440        450        460        470        480 
PSDPSYEDMR EIVCMKKLRP SFPNRWSSDE CLRQMGKLMT ECWAQNPASR LTALRVKKTL 

       490 
AKMSESQDIK L 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE24260.1.
Tissue: Corpora quadrigemina EMBL BAE24260.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK140158 mRNA. Translation: BAE24260.1.
RefSeqNP_001264149.1. NM_001277220.1.
UniGeneMm.39089.

3D structure databases

ProteinModelPortalQ3USS1.
SMRQ3USS1. Positions 37-102, 163-489.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000101839.

Proteomic databases

PRIDEQ3USS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID12167.
KEGGmmu:12167.
UCSCuc008roh.1. mouse.

Organism-specific databases

CTD658.
MGIMGI:107191. Bmpr1b.

Phylogenomic databases

HOVERGENHBG054502.
InParanoidQ3USS1.
KOK13578.

Gene expression databases

GenevestigatorQ3USS1.

Family and domain databases

InterProIPR000472. Activin_rcpt.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR003605. TGF_beta_rcpt_GS.
IPR000333. TGFB_receptor.
[Graphical view]
PANTHERPTHR23255. PTHR23255. 1 hit.
PfamPF01064. Activin_recp. 1 hit.
PF00069. Pkinase. 1 hit.
PF08515. TGF_beta_GS. 1 hit.
[Graphical view]
SMARTSM00467. GS. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51256. GS. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSBMPR1B. mouse.
SOURCESearch...

Entry information

Entry nameQ3USS1_MOUSE
AccessionPrimary (citable) accession number: Q3USS1
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)