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Protein

Amino acid transporter

Gene

Slc1a4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Amino acid transporterUniRule annotation
Gene namesi
Name:Slc1a4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2135601. Slc1a4.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei43 – 6523HelicalUniRule annotationAdd
BLAST
Transmembranei86 – 10520HelicalUniRule annotationAdd
BLAST
Transmembranei117 – 13923HelicalUniRule annotationAdd
BLAST
Transmembranei218 – 23720HelicalUniRule annotationAdd
BLAST
Transmembranei257 – 27721HelicalUniRule annotationAdd
BLAST
Transmembranei297 – 32024HelicalUniRule annotationAdd
BLAST
Transmembranei326 – 34924HelicalUniRule annotationAdd
BLAST
Transmembranei369 – 39426HelicalUniRule annotationAdd
BLAST
Transmembranei406 – 43530HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ3US35.
PRIDEiQ3US35.

Expressioni

Gene expression databases

GenevisibleiQ3US35. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105223.

Structurei

3D structure databases

ProteinModelPortaliQ3US35.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3787. Eukaryota.
COG1301. LUCA.
HOVERGENiHBG000080.
KOiK05615.

Family and domain databases

Gene3Di1.10.3860.10. 2 hits.
InterProiIPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 2 hits.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3US35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKSGETNGY LDGTQAEPAA GPRTPETAMG KSQRCASFFR RHALVLLTVS
60 70 80 90 100
GVLVGAGMGA ALRGLQLTRT QITYLAFPGE MLLRMLRMII LPLVVCSLVS
110 120 130 140 150
GAASLDASSL GRLGGIAVAY FGLTTLSASA LAVALAFIIK PGAGAQTLQS
160 170 180 190 200
SSLGLENSGP PPVSKETVDS FLDLLRNLFP SNLVVAAFTT SATDYTVVTH
210 220 230 240 250
NTSSGNVTKE KIHVVTDVEG MNILGLVLFA LVLGVALKKL GPEGEDLIRF
260 270 280 290 300
FNSFNEATMV LVSWIMWYVP IGIMFLIGSK IVEMKDIVML VTSLGKYIFA
310 320 330 340 350
SMLGHVIHGG IVLPLVYFAF TRKNPFTFLL GLLTPFATAF ATCSSSATLP
360 370 380 390 400
SMMKCIEENN GVDKRISRFI LPIGATVNMD GAAIFQCVAA VFIAQLNNVD
410 420 430 440 450
LNAGQIFTIL VTATASSVGA AGVPAGGVLT IAIILEAIGL PTHDLSLILA
460 470 480 490 500
VDWIVDRTTT VVNVEGDALG AGILNHLNQK VVKKGEQELQ EVKVEAIPNS
510 520 530
KSEEETSPLV THQNPAGPVA IAPELESKES VL
Length:532
Mass (Da):56,102
Last modified:October 11, 2005 - v1
Checksum:i44311BA259A35D21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK140866 mRNA. Translation: BAE24502.1.
RefSeqiNP_061349.3. NM_018861.3.
UniGeneiMm.6379.

Genome annotation databases

GeneIDi55963.
KEGGimmu:55963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK140866 mRNA. Translation: BAE24502.1.
RefSeqiNP_061349.3. NM_018861.3.
UniGeneiMm.6379.

3D structure databases

ProteinModelPortaliQ3US35.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105223.

Proteomic databases

PaxDbiQ3US35.
PRIDEiQ3US35.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi55963.
KEGGimmu:55963.

Organism-specific databases

CTDi6509.
MGIiMGI:2135601. Slc1a4.

Phylogenomic databases

eggNOGiKOG3787. Eukaryota.
COG1301. LUCA.
HOVERGENiHBG000080.
KOiK05615.

Miscellaneous databases

ChiTaRSiSlc1a4. mouse.
SOURCEiSearch...

Gene expression databases

GenevisibleiQ3US35. MM.

Family and domain databases

Gene3Di1.10.3860.10. 2 hits.
InterProiIPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 2 hits.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3US35_MOUSE
AccessioniPrimary (citable) accession number: Q3US35
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.