Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger and SCAN domain-containing protein 10

Gene

Zscan10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.3 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri292 – 31524C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri321 – 34323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri349 – 37123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri377 – 39923C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri421 – 44323C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri467 – 48923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri495 – 51723C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri523 – 54523C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri551 – 57323C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri579 – 60123C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri607 – 62923C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri635 – 65723C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri669 – 69123C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri697 – 71923C2H2-type 14PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • sequence-specific DNA binding Source: UniProtKB
  • transcription factor activity, sequence-specific DNA binding Source: UniProtKB

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: UniProtKB
  • stem cell differentiation Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger and SCAN domain-containing protein 10
Alternative name(s):
Zinc finger protein 206
Gene namesi
Name:Zscan10
Synonyms:Zfp206
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:3040700. Zscan10.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 782782Zinc finger and SCAN domain-containing protein 10PRO_0000394248Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei160 – 1601PhosphoserineBy similarity
Modified residuei206 – 2061PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ3URR7.
PRIDEiQ3URR7.

PTM databases

iPTMnetiQ3URR7.

Expressioni

Tissue specificityi

Embryonic stem (ES) cell-specific. Not expressed in adult, except in testis.2 Publications

Developmental stagei

Expressed throughout embryogenesis.1 Publication

Inductioni

Transcriptionally regulated by POU5F1/OCT4 and SOX2.1 Publication

Gene expression databases

BgeeiQ3URR7.
ExpressionAtlasiQ3URR7. baseline and differential.
GenevisibleiQ3URR7. MM.

Interactioni

Subunit structurei

Interacts with POU5F1/OCT4 and SOX2.1 Publication

Protein-protein interaction databases

BioGridi237126. 1 interaction.
STRINGi10090.ENSMUSP00000093255.

Structurei

Secondary structure

1
782
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi39 – 479Combined sources
Turni53 – 553Combined sources
Helixi57 – 7216Combined sources
Turni74 – 763Combined sources
Helixi79 – 9315Combined sources
Helixi97 – 1004Combined sources
Helixi101 – 1033Combined sources
Helixi111 – 1166Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E6SX-ray1.85A36-128[»]
ProteinModelPortaliQ3URR7.
SMRiQ3URR7. Positions 36-117, 340-778.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7171SCAN boxPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi104 – 17572Pro-richAdd
BLAST

Sequence similaritiesi

Contains 14 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 SCAN box domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri292 – 31524C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri321 – 34323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri349 – 37123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri377 – 39923C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri421 – 44323C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri467 – 48923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri495 – 51723C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri523 – 54523C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri551 – 57323C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri579 – 60123C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri607 – 62923C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri635 – 65723C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri669 – 69123C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri697 – 71923C2H2-type 14PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111047.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
InParanoidiQ3URR7.
KOiK09230.
OMAiERPHACH.
OrthoDBiEOG7KSX7Q.
PhylomeDBiQ3URR7.
TreeFamiTF338010.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 3 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 14 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 14 hits.
PS50157. ZINC_FINGER_C2H2_2. 14 hits.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q3URR7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLAEPVPDAL EQEHPGAVKL EEDEVGEEDP RLAESRPRPE VAHQLFRCFQ
60 70 80 90 100
YQEDMGPRAS LGRLRELCNH WLRPALHTKK QILELLVLEQ FLSVLPPHVL
110 120 130 140 150
SRLHGQPLRD GEEVVQLLEG VPRDISHMGP LDFSFSAGKN APADIISEEQ
160 170 180 190 200
NSPSQVPSHS PQTELPSEEI PALHPLNELP PPQPAPIRPA EPEEWRLAPS
210 220 230 240 250
SNWPMSPEPQ EILQDPRESN PSQGPSWLEE NSRDQELAAV LESLTFEDTS
260 270 280 290 300
EKRAWPANPL GFGSRMPDNE ELKVEEPKVT TWPVVIGAES QTEKPEVAGE
310 320 330 340 350
PLTQTVGQET SSTGWGGTPA DGSEVVKVRG ASDAPEPQGE MQFICTYCGV
360 370 380 390 400
NFPEMSHLQA HQLQSHPNLQ PHPSSRSFRC LWCGKTFGRS SILKLHMRTH
410 420 430 440 450
TDERPHACHL CNRRFRQSSH LTKHLLTHSS EPAFRCAECN QGFQRRSSLM
460 470 480 490 500
QHLLAHAQGK NLTPNPEGKT KVPEMAAVLC SHCGQTFKRR SSLKRHLRNH
510 520 530 540 550
AKDKDHLSSE DPGSLSSSQE SNPYVCSDCG KAFRQSEQLM IHTRRVHTRE
560 570 580 590 600
RPFSCQVCGR CFTQNSQLIS HQQIHTGEKP HACPQCSKRF VRRAGLARHL
610 620 630 640 650
LTHGSLRPYH CAQCGKSFRQ MRDLTRHVRC HTGEKPCRCN ECGEGFTQNA
660 670 680 690 700
HLARHQRIHT GEKPHACDIC GHRFRNSSNL ARHRRSHTGE RPYSCPTCGR
710 720 730 740 750
SFRRNAHLQR HLITHTGSKQ EKEVPQECPE CGKSFNRSCN LLRHLLVHTG
760 770 780
ARPYSCALCG RSFSRNSHLL RHLRTHARES LY
Length:782
Mass (Da):88,355
Last modified:May 18, 2010 - v2
Checksum:iB521507A5C617AED
GO
Isoform 2 (identifier: Q3URR7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     328-359: Missing.

Show »
Length:750
Mass (Da):84,831
Checksum:i18305E8F8E15CB34
GO
Isoform 3 (identifier: Q3URR7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-240: Missing.

Show »
Length:672
Mass (Da):76,254
Checksum:i0A8101311BFA9C49
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti306 – 3061V → E in ABC54589 (PubMed:16971461).Curated
Sequence conflicti306 – 3061V → E in ABC54590 (PubMed:16971461).Curated
Sequence conflicti306 – 3061V → E in ABC54591 (PubMed:16971461).Curated
Sequence conflicti306 – 3061V → E in ABM45916 (PubMed:17628018).Curated
Sequence conflicti306 – 3061V → E in EDL22251 (Ref. 4) Curated
Sequence conflicti546 – 5461V → L in BAE24621 (PubMed:16141072).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei131 – 240110Missing in isoform 3. 1 PublicationVSP_039227Add
BLAST
Alternative sequencei328 – 35932Missing in isoform 2. 2 PublicationsVSP_039228Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ323929 mRNA. Translation: ABC54589.1.
DQ323930 mRNA. Translation: ABC54590.1.
DQ323931 mRNA. Translation: ABC54591.1.
EF152498 mRNA. Translation: ABM45916.1.
AK141259 mRNA. Translation: BAE24621.1.
CH466606 Genomic DNA. Translation: EDL22251.1.
BC145638 mRNA. Translation: AAI45639.1.
CCDSiCCDS28451.1. [Q3URR7-1]
CCDS70766.1. [Q3URR7-2]
CCDS79510.1. [Q3URR7-3]
RefSeqiNP_001028597.2. NM_001033425.4. [Q3URR7-1]
NP_001276410.1. NM_001289481.1. [Q3URR7-2]
NP_001276411.1. NM_001289482.1. [Q3URR7-3]
NP_001276412.1. NM_001289483.1.
NP_001276413.1. NM_001289484.1.
XP_011244806.1. XM_011246504.1. [Q3URR7-1]
XP_011244807.1. XM_011246505.1. [Q3URR7-1]
UniGeneiMm.270315.

Genome annotation databases

EnsembliENSMUST00000095595; ENSMUSP00000093255; ENSMUSG00000023902. [Q3URR7-1]
ENSMUST00000115509; ENSMUSP00000111171; ENSMUSG00000023902. [Q3URR7-3]
ENSMUST00000120967; ENSMUSP00000113386; ENSMUSG00000023902. [Q3URR7-2]
GeneIDi332221.
KEGGimmu:332221.
UCSCiuc008ask.3. mouse. [Q3URR7-2]
uc008asl.2. mouse. [Q3URR7-1]
uc008asm.2. mouse. [Q3URR7-3]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ323929 mRNA. Translation: ABC54589.1.
DQ323930 mRNA. Translation: ABC54590.1.
DQ323931 mRNA. Translation: ABC54591.1.
EF152498 mRNA. Translation: ABM45916.1.
AK141259 mRNA. Translation: BAE24621.1.
CH466606 Genomic DNA. Translation: EDL22251.1.
BC145638 mRNA. Translation: AAI45639.1.
CCDSiCCDS28451.1. [Q3URR7-1]
CCDS70766.1. [Q3URR7-2]
CCDS79510.1. [Q3URR7-3]
RefSeqiNP_001028597.2. NM_001033425.4. [Q3URR7-1]
NP_001276410.1. NM_001289481.1. [Q3URR7-2]
NP_001276411.1. NM_001289482.1. [Q3URR7-3]
NP_001276412.1. NM_001289483.1.
NP_001276413.1. NM_001289484.1.
XP_011244806.1. XM_011246504.1. [Q3URR7-1]
XP_011244807.1. XM_011246505.1. [Q3URR7-1]
UniGeneiMm.270315.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E6SX-ray1.85A36-128[»]
ProteinModelPortaliQ3URR7.
SMRiQ3URR7. Positions 36-117, 340-778.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi237126. 1 interaction.
STRINGi10090.ENSMUSP00000093255.

PTM databases

iPTMnetiQ3URR7.

Proteomic databases

PaxDbiQ3URR7.
PRIDEiQ3URR7.

Protocols and materials databases

DNASUi332221.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000095595; ENSMUSP00000093255; ENSMUSG00000023902. [Q3URR7-1]
ENSMUST00000115509; ENSMUSP00000111171; ENSMUSG00000023902. [Q3URR7-3]
ENSMUST00000120967; ENSMUSP00000113386; ENSMUSG00000023902. [Q3URR7-2]
GeneIDi332221.
KEGGimmu:332221.
UCSCiuc008ask.3. mouse. [Q3URR7-2]
uc008asl.2. mouse. [Q3URR7-1]
uc008asm.2. mouse. [Q3URR7-3]

Organism-specific databases

CTDi84891.
MGIiMGI:3040700. Zscan10.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000111047.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
InParanoidiQ3URR7.
KOiK09230.
OMAiERPHACH.
OrthoDBiEOG7KSX7Q.
PhylomeDBiQ3URR7.
TreeFamiTF338010.

Miscellaneous databases

PROiQ3URR7.
SOURCEiSearch...

Gene expression databases

BgeeiQ3URR7.
ExpressionAtlasiQ3URR7. baseline and differential.
GenevisibleiQ3URR7. MM.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 3 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 14 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 14 hits.
PS50157. ZINC_FINGER_C2H2_2. 14 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    Strain: 129S1/Sv.
  2. "Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells."
    Wang Z.X., Kueh J.L., Teh C.H., Rossbach M., Lim L., Li P., Wong K.Y., Lufkin T., Robson P., Stanton L.W.
    Stem Cells 25:2173-2182(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Strain: 129P2.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: C57BL/6J.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Brain.
  6. "Oct4 and Sox2 directly regulate expression of another pluripotency transcription factor, Zfp206, in embryonic stem cells."
    Wang Z.X., Teh C.H., Kueh J.L., Lufkin T., Robson P., Stanton L.W.
    J. Biol. Chem. 282:12822-12830(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  7. "Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells."
    Yu H.B., Kunarso G., Hong F.H., Stanton L.W.
    J. Biol. Chem. 284:31327-31335(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DNA-BINDING, INTERACTION WITH POU5F1 AND SOX2.

Entry informationi

Entry nameiZSC10_MOUSE
AccessioniPrimary (citable) accession number: Q3URR7
Secondary accession number(s): B7ZP53
, Q20D61, Q20D62, Q20D63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: May 18, 2010
Last modified: June 8, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.