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Protein
Submitted name:

NK2 transcription factor related, locus 5 (Drosophila)

Gene

Nkx2-5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NK2 transcription factor related, locus 5 (Drosophila)Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Nkx2-5Imported
ORF Names:mCG_1575Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97350. Nkx2-5.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiQ3UQU2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000015579.
ExpressionAtlasiQ3UQU2. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3UQU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 195Homeobox DNA-bindingInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
HOVERGENiHBG006689.
KOiK09345.
OMAiDKKELCA.
OrthoDBiEOG091G0LZ2.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR033629. NKX-2.5.
PANTHERiPTHR24340:SF49. PTHR24340:SF49. 1 hit.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UQU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPSPALTPT PFSVKDILNL EQQQRSLASG DLSARLEATL APASCMLAAF
60 70 80 90 100
KPEAYSGPEA AASGLAELRA EMGPAPSPPK CSPAFPAAPT FYPGAYGDPD
110 120 130 140 150
PAKDPRADKK ELCALQKAVE LDKAETDGAE RPRARRRRKP RVLFSQAQVY
160 170 180 190 200
ELERRFKQQR YLSAPERDQL ASVLKLTSTQ VKIWFQNRRY KCKRQRQDQT
210 220 230 240 250
LELLGPPPPP ARRIAVPVLV RDGKPCLGDP AAYAPAYGVG LNAYGYNAYP
260 270 280 290 300
YPSYGGAACS PGYSCAAYPA APPAAQPPAA SANSNFVNFG VGDLNTVQSP
310
GMPQGNSGVS TLHGIRAW
Length:318
Mass (Da):34,163
Last modified:October 11, 2005 - v1
Checksum:i6A3E7859F46D4FA6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC139299 mRNA. Translation: AAI39300.1.
BC139303 mRNA. Translation: AAI39304.1.
AK142146 mRNA. Translation: BAE24947.1.
CH466606 Genomic DNA. Translation: EDL22517.1.
RefSeqiNP_032726.1. NM_008700.2.
XP_006523860.1. XM_006523797.3.
UniGeneiMm.41974.

Genome annotation databases

GeneIDi18091.
KEGGimmu:18091.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ3UQU2_MOUSE
AccessioniPrimary (citable) accession number: Q3UQU2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 5, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)