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Q3UQI9 (F188B_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein FAM188B
Gene names
Name:Fam188b
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length744 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the FAM188 family.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q3UQI9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q3UQI9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     506-744: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 744744Protein FAM188B
PRO_0000320591

Natural variations

Alternative sequence506 – 744239Missing in isoform 2.
VSP_031672

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 5AF10D14154B3241

FASTA74482,937
        10         20         30         40         50         60 
MDSLYVEEVA ASLVREFLSR KGLNKTFVTM DQERPRCELS INSRNDLRKV LHLEFLYKEN 

        70         80         90        100        110        120 
KAKEKPLRTN LELITRYFLD NVGNTDNSES QEVPIPAIPV PKKNNKLPLR HSETTLVNIY 

       130        140        150        160        170        180 
DLSDEDTGRR TSWSEAGKAR HDSLDGDILG NFVSSKKPSH KSKAAHVDLG DSLPLVPAWE 

       190        200        210        220        230        240 
KVDQLHSSEP GIDVKKTMER TRPKSGLIVR GMMAGPVASS PQDSFRKRSL RRSSALSRKL 

       250        260        270        280        290        300 
QTPEEIQQQS EPFVHTPAYL GPQEVPDSSS DSVSRSPLGQ LNELSIEKPN VTSSSQGLSQ 

       310        320        330        340        350        360 
RDRPRLRSVS EDSPLGYSHT EGNSRMAQDQ LERAFKRQGV QPPSLRKNQL VSDRTDDKPD 

       370        380        390        400        410        420 
ALQLEDVEDE LIKEDIVLFP PPSMLKLQTV SKPIDLSLAK EIKTLLFGST FCCFSEEWKL 

       430        440        450        460        470        480 
QNFSFNDIAS LKYGIVQNKG GPCGVLAAVQ GCVLQKLLFE GDNRTNSNLR LQPSDAQRTR 

       490        500        510        520        530        540 
CLALAIADIL WRAGGKEQAV VALASGTPHF SPTGKYKADG VLETLTLYSL TSSEDLVTFI 

       550        560        570        580        590        600 
QQSVHQFEAG PYGCILLTLS AILSRSLELV RQDFDVPTSH LIGAHGYCTQ ELVNLLLTGR 

       610        620        630        640        650        660 
AVSNVFNDVV ELDSGDGNIT LLRGIEARSD IGFLSLFEHY NVCQVGCFLK TPRFPIWVVC 

       670        680        690        700        710        720 
SESHFSILFS LQPELLCDWR SERLFDLYYY DGLANQQEEI RLTVDTTKTA PADSCSDLVP 

       730        740 
PLELCIRTKW KGASVNWNGS DPIL 

« Hide

Isoform 2 [UniParc].

Checksum: 53793DA5EF2BF566
Show »

FASTA50556,325

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
Strain: C57BL/6J.
Tissue: Lung.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK082855 mRNA. Translation: BAC38655.1.
AK142385 mRNA. Translation: BAE25052.1.
CCDSCCDS51782.1. [Q3UQI9-1]
RefSeqNP_001136253.1. NM_001142781.1. [Q3UQI9-1]
NP_808551.2. NM_177883.4.
UniGeneMm.268997.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid236942. 1 interaction.

PTM databases

PhosphoSiteQ3UQI9.

Proteomic databases

PaxDbQ3UQI9.
PRIDEQ3UQI9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000053094; ENSMUSP00000061221; ENSMUSG00000038022. [Q3UQI9-1]
GeneID330323.
KEGGmmu:330323.
UCSCuc009cao.1. mouse. [Q3UQI9-1]

Organism-specific databases

CTD84182.
MGIMGI:3583959. Fam188b.

Phylogenomic databases

eggNOGNOG282176.
GeneTreeENSGT00530000063283.
HOGENOMHOG000111604.
InParanoidQ3UQI9.
OMANWNGSDP.
OrthoDBEOG7GJ6CM.
PhylomeDBQ3UQI9.
TreeFamTF323996.

Gene expression databases

BgeeQ3UQI9.
CleanExMM_C330043M08RIK.
GenevestigatorQ3UQI9.

Family and domain databases

InterProIPR025257. DUF4205.
[Graphical view]
PfamPF13898. DUF4205. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio399298.
PROQ3UQI9.
SOURCESearch...

Entry information

Entry nameF188B_MOUSE
AccessionPrimary (citable) accession number: Q3UQI9
Secondary accession number(s): Q8C472
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 11, 2005
Last modified: July 9, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot