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Q3UPZ0 (Q3UPZ0_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Sema domain, seven thrombospondin repeats (Type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (Semaphorin) 5A, isoform CRA_a EMBL EDL08867.1
Submitted name:
Semaphorin-5A Ensembl ENSMUSP00000069024
Gene names
Name:Sema5a EMBL EDL08867.1 Ensembl ENSMUSP00000069024 MGI 107556
ORF Names:mCG_141513 EMBL EDL08867.1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length1074 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 Sema domain. SAAS SAAS002165

Sequences

Sequence LengthMass (Da)Tools
Q3UPZ0 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 3A231A2E0D880C1C

FASTA1,074120,321
        10         20         30         40         50         60 
MKGACILAWL FSSLGVWRLA RPETQDPAKC QRAEHPVVSY KEIGPWLREF RAENAVDFSR 

        70         80         90        100        110        120 
LTFDPGQKEL VVGARNYLFR LELEDLSLIQ AVEWECDEAT KKACYSKGKS KEECQNYIRV 

       130        140        150        160        170        180 
LLVGGDRLFT CGTNAFTPVC TIRSLSNLTE IHDQISGMAR CPYSPQHNST ALLTASGELY 

       190        200        210        220        230        240 
AATAMDFPGR DPAIYRSLGT LPPLRTAQYN SKWLNEPNFV SSYDIGNFTY FFFRENAVEH 

       250        260        270        280        290        300 
DCGKTVFSRA ARVCKNDIGG RFLLEDTWTT FMKARLNCSR PGEVPFYYNE LQGTFFLPEL 

       310        320        330        340        350        360 
DLIYGIFTTN VNSIAASAVC VFNLSAISQA FNGPFKYQEN SRSAWLPYPN PNPNFQCGTM 

       370        380        390        400        410        420 
DQGLYVNLTE RNLQDAQKFI LMHEVVQPVT TVPSFMEDNS RFSHLAVDVV QGRETLVHII 

       430        440        450        460        470        480 
YLATDYGTIK KVRAPLSQSS GSCLLEEIEL FPERRSEPIR SLQILHSQSV LFVGLQEHVA 

       490        500        510        520        530        540 
KIPLKRCHFH QTRSACIGAQ DPYCGWDAVM KKCTSLEESL SMTQWDQSIP TCPTRNLTVD 

       550        560        570        580        590        600 
GSFGPWSPWT PCTHTDGTAV GSCLCRSRSC DSPAPQCGGW QCEGPRMEIT NCSRNGGWTP 

       610        620        630        640        650        660 
WTSWSPCSTT CGIGFQVRQR SCSNPTPRHG GRVCVGQNRE ERYCNEHLLC PPHVFWTGWG 

       670        680        690        700        710        720 
PWERCTAQCG GGIQARRRTC ENGPDCAGCN VEYQPCNTNA CPELKKTTPW TPWTPVNISD 

       730        740        750        760        770        780 
NGGHYEQRFR YTCKARLPDP NLLEVGRQRI EMRYCSSDGT SGCSTDGLSG DFLRAGRYSA 

       790        800        810        820        830        840 
HTVNGAWSAW TSWSQCSRDC SRGIRNRKRV CNNPEPKFGG MPCLGPSLEF QECNILPCPV 

       850        860        870        880        890        900 
DGVWSCWSSW SKCSATCGGG HYMRTRSCSN PAPAYGGDIC LGLHTEEALC NTQTCPESWS 

       910        920        930        940        950        960 
EWSDWSVCDA SGTQVRARQC ILLFPVGSQC SGNTTESRPC VFDSNFIPEV SVARSSSVEE 

       970        980        990       1000       1010       1020 
KRCGEFNMFH MMAVGLSSSI LGCLLTLLVY TYCQRYQQQS HDATVIHPVS PAALNSSITN 

      1030       1040       1050       1060       1070 
HINKLDKYDS VEAIKAFNKN NLILEERNKY FNPHLTGKTY SNAYFTDLNN YDEY

« Hide

References

« Hide 'large scale' references
[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[6]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL08867.1.
[7]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[8]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[9]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE25254.1.
Tissue: Hippocampus EMBL BAE24765.1 and Lung EMBL BAE25254.1.
[10]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL08867.1.
[11]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000069024.
[12]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000069024.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC110236 Genomic DNA. No translation available.
AC113289 Genomic DNA. No translation available.
AC137123 Genomic DNA. No translation available.
AK141612 mRNA. Translation: BAE24765.1.
AK143026 mRNA. Translation: BAE25254.1.
CH466541 Genomic DNA. Translation: EDL08867.1.
IPIIPI00875846.
RefSeqNP_033180.2. NM_009154.2.
UniGeneMm.260374.

3D structure databases

SMRQ3UPZ0. Positions 68-506, 540-647, 649-703, 783-940.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000067458; ENSMUSP00000069024; ENSMUSG00000022231.
GeneID20356.
KEGGmmu:20356.
UCSCuc007vku.1. mouse.

Organism-specific databases

CTD9037.
MGIMGI:107556. Sema5a.

Phylogenomic databases

GeneTreeENSGT00690000101974.
HOVERGENHBG062356.
InParanoidQ3UPZ0.
KOK06841.
OMADSNFIPE.

Gene expression databases

GenevestigatorQ3UPZ0.

Family and domain databases

Gene3D2.130.10.10. 1 hit.
InterProIPR003659. Plexin-like.
IPR016201. Plexin-like_fold.
IPR002165. Plexin_repeat.
IPR027231. Semaphorin.
IPR001627. Semaphorin/CD100_Ag.
IPR000884. Thrombospondin_1_rpt.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERPTHR11036. PTHR11036. 1 hit.
PfamPF01437. PSI. 1 hit.
PF01403. Sema. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view]
SMARTSM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
SM00209. TSP1. 6 hits.
[Graphical view]
SUPFAMSSF103575. Plexin-like_fold. 1 hit.
SSF101912. Sema. 1 hit.
SSF82895. TSP1. 6 hits.
PROSITEPS51004. SEMA. 1 hit.
PS50092. TSP1. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio298229.
SOURCESearch...

Entry information

Entry nameQ3UPZ0_MOUSE
AccessionPrimary (citable) accession number: Q3UPZ0
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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