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Q3UPZ0

- Q3UPZ0_MOUSE

UniProt

Q3UPZ0 - Q3UPZ0_MOUSE

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Protein
Submitted name:

Sema domain, seven thrombospondin repeats (Type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (Semaphorin) 5A, isoform CRA_a

Gene
Sema5a, mCG_141513
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. axon guidance receptor activity Source: MGI

GO - Biological processi

  1. axon guidance Source: MGI
  2. branching morphogenesis of an epithelial tube Source: MGI
  3. patterning of blood vessels Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sema domain, seven thrombospondin repeats (Type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (Semaphorin) 5A, isoform CRA_aImported
Submitted name:
Semaphorin-5AImported
Gene namesi
Name:Sema5aImported
ORF Names:mCG_141513Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:107556. Sema5a.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriQ3UPZ0.

Family & Domainsi

Sequence similaritiesi

Contains Sema domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00690000101974.
HOVERGENiHBG062356.
InParanoidiQ3UPZ0.
KOiK06841.
OMAiYSNAYFT.
OrthoDBiEOG7SN8C0.
TreeFamiTF329951.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR016201. Plexin-like_fold.
IPR002165. Plexin_repeat.
IPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR000884. Thrombospondin_1_rpt.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 1 hit.
PfamiPF01437. PSI. 1 hit.
PF01403. Sema. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view]
SMARTiSM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
SM00209. TSP1. 6 hits.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
SSF103575. SSF103575. 1 hit.
SSF82895. SSF82895. 6 hits.
PROSITEiPS51004. SEMA. 1 hit.
PS50092. TSP1. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UPZ0-1 [UniParc]FASTAAdd to Basket

« Hide

MKGACILAWL FSSLGVWRLA RPETQDPAKC QRAEHPVVSY KEIGPWLREF     50
RAENAVDFSR LTFDPGQKEL VVGARNYLFR LELEDLSLIQ AVEWECDEAT 100
KKACYSKGKS KEECQNYIRV LLVGGDRLFT CGTNAFTPVC TIRSLSNLTE 150
IHDQISGMAR CPYSPQHNST ALLTASGELY AATAMDFPGR DPAIYRSLGT 200
LPPLRTAQYN SKWLNEPNFV SSYDIGNFTY FFFRENAVEH DCGKTVFSRA 250
ARVCKNDIGG RFLLEDTWTT FMKARLNCSR PGEVPFYYNE LQGTFFLPEL 300
DLIYGIFTTN VNSIAASAVC VFNLSAISQA FNGPFKYQEN SRSAWLPYPN 350
PNPNFQCGTM DQGLYVNLTE RNLQDAQKFI LMHEVVQPVT TVPSFMEDNS 400
RFSHLAVDVV QGRETLVHII YLATDYGTIK KVRAPLSQSS GSCLLEEIEL 450
FPERRSEPIR SLQILHSQSV LFVGLQEHVA KIPLKRCHFH QTRSACIGAQ 500
DPYCGWDAVM KKCTSLEESL SMTQWDQSIP TCPTRNLTVD GSFGPWSPWT 550
PCTHTDGTAV GSCLCRSRSC DSPAPQCGGW QCEGPRMEIT NCSRNGGWTP 600
WTSWSPCSTT CGIGFQVRQR SCSNPTPRHG GRVCVGQNRE ERYCNEHLLC 650
PPHVFWTGWG PWERCTAQCG GGIQARRRTC ENGPDCAGCN VEYQPCNTNA 700
CPELKKTTPW TPWTPVNISD NGGHYEQRFR YTCKARLPDP NLLEVGRQRI 750
EMRYCSSDGT SGCSTDGLSG DFLRAGRYSA HTVNGAWSAW TSWSQCSRDC 800
SRGIRNRKRV CNNPEPKFGG MPCLGPSLEF QECNILPCPV DGVWSCWSSW 850
SKCSATCGGG HYMRTRSCSN PAPAYGGDIC LGLHTEEALC NTQTCPESWS 900
EWSDWSVCDA SGTQVRARQC ILLFPVGSQC SGNTTESRPC VFDSNFIPEV 950
SVARSSSVEE KRCGEFNMFH MMAVGLSSSI LGCLLTLLVY TYCQRYQQQS 1000
HDATVIHPVS PAALNSSITN HINKLDKYDS VEAIKAFNKN NLILEERNKY 1050
FNPHLTGKTY SNAYFTDLNN YDEY 1074
Length:1,074
Mass (Da):120,321
Last modified:October 11, 2005 - v1
Checksum:i3A231A2E0D880C1C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC110236 Genomic DNA. No translation available.
AC113289 Genomic DNA. No translation available.
AC137123 Genomic DNA. No translation available.
AK141612 mRNA. Translation: BAE24765.1.
AK143026 mRNA. Translation: BAE25254.1.
CH466541 Genomic DNA. Translation: EDL08867.1.
RefSeqiNP_033180.2. NM_009154.2.
XP_006520106.1. XM_006520043.1.
XP_006520107.1. XM_006520044.1.
UniGeneiMm.260374.

Genome annotation databases

EnsembliENSMUST00000067458; ENSMUSP00000069024; ENSMUSG00000022231.
GeneIDi20356.
KEGGimmu:20356.
UCSCiuc007vku.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC110236 Genomic DNA. No translation available.
AC113289 Genomic DNA. No translation available.
AC137123 Genomic DNA. No translation available.
AK141612 mRNA. Translation: BAE24765.1 .
AK143026 mRNA. Translation: BAE25254.1 .
CH466541 Genomic DNA. Translation: EDL08867.1 .
RefSeqi NP_033180.2. NM_009154.2.
XP_006520106.1. XM_006520043.1.
XP_006520107.1. XM_006520044.1.
UniGenei Mm.260374.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000067458 ; ENSMUSP00000069024 ; ENSMUSG00000022231 .
GeneIDi 20356.
KEGGi mmu:20356.
UCSCi uc007vku.1. mouse.

Organism-specific databases

CTDi 9037.
MGIi MGI:107556. Sema5a.

Phylogenomic databases

GeneTreei ENSGT00690000101974.
HOVERGENi HBG062356.
InParanoidi Q3UPZ0.
KOi K06841.
OMAi YSNAYFT.
OrthoDBi EOG7SN8C0.
TreeFami TF329951.

Miscellaneous databases

NextBioi 298229.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3UPZ0.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR016201. Plexin-like_fold.
IPR002165. Plexin_repeat.
IPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR000884. Thrombospondin_1_rpt.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
PANTHERi PTHR11036. PTHR11036. 1 hit.
Pfami PF01437. PSI. 1 hit.
PF01403. Sema. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view ]
SMARTi SM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
SM00209. TSP1. 6 hits.
[Graphical view ]
SUPFAMi SSF101912. SSF101912. 1 hit.
SSF103575. SSF103575. 1 hit.
SSF82895. SSF82895. 6 hits.
PROSITEi PS51004. SEMA. 1 hit.
PS50092. TSP1. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and LungImported.
  10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  12. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3UPZ0_MOUSE
AccessioniPrimary (citable) accession number: Q3UPZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi