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Protein
Submitted name:

Sema domain, seven thrombospondin repeats (Type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (Semaphorin) 5A, isoform CRA_a

Gene

Sema5a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-416700. Other semaphorin interactions.

Names & Taxonomyi

Protein namesi
Submitted name:
Sema domain, seven thrombospondin repeats (Type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (Semaphorin) 5A, isoform CRA_aImported
Submitted name:
Semaphorin-5AImported
Gene namesi
Name:Sema5aImported
ORF Names:mCG_141513Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:107556. Sema5a.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei968 – 990HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500878032523 – 1074Sequence analysisAdd BLAST1052

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000022231.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069024.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 484SemaInterPro annotationAdd BLAST450

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3611. Eukaryota.
ENOG410XQZC. LUCA.
GeneTreeiENSGT00760000119134.
HOVERGENiHBG062356.
KOiK06841.
OMAiLLVYTYC.
OrthoDBiEOG091G01T5.
TreeFamiTF329951.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR016201. PSI.
IPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR000884. TSP1_rpt.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 4 hits.
PfamiPF01403. Sema. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view]
SMARTiSM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
SM00209. TSP1. 6 hits.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
SSF82895. SSF82895. 6 hits.
PROSITEiPS51004. SEMA. 1 hit.
PS50092. TSP1. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UPZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGACILAWL FSSLGVWRLA RPETQDPAKC QRAEHPVVSY KEIGPWLREF
60 70 80 90 100
RAENAVDFSR LTFDPGQKEL VVGARNYLFR LELEDLSLIQ AVEWECDEAT
110 120 130 140 150
KKACYSKGKS KEECQNYIRV LLVGGDRLFT CGTNAFTPVC TIRSLSNLTE
160 170 180 190 200
IHDQISGMAR CPYSPQHNST ALLTASGELY AATAMDFPGR DPAIYRSLGT
210 220 230 240 250
LPPLRTAQYN SKWLNEPNFV SSYDIGNFTY FFFRENAVEH DCGKTVFSRA
260 270 280 290 300
ARVCKNDIGG RFLLEDTWTT FMKARLNCSR PGEVPFYYNE LQGTFFLPEL
310 320 330 340 350
DLIYGIFTTN VNSIAASAVC VFNLSAISQA FNGPFKYQEN SRSAWLPYPN
360 370 380 390 400
PNPNFQCGTM DQGLYVNLTE RNLQDAQKFI LMHEVVQPVT TVPSFMEDNS
410 420 430 440 450
RFSHLAVDVV QGRETLVHII YLATDYGTIK KVRAPLSQSS GSCLLEEIEL
460 470 480 490 500
FPERRSEPIR SLQILHSQSV LFVGLQEHVA KIPLKRCHFH QTRSACIGAQ
510 520 530 540 550
DPYCGWDAVM KKCTSLEESL SMTQWDQSIP TCPTRNLTVD GSFGPWSPWT
560 570 580 590 600
PCTHTDGTAV GSCLCRSRSC DSPAPQCGGW QCEGPRMEIT NCSRNGGWTP
610 620 630 640 650
WTSWSPCSTT CGIGFQVRQR SCSNPTPRHG GRVCVGQNRE ERYCNEHLLC
660 670 680 690 700
PPHVFWTGWG PWERCTAQCG GGIQARRRTC ENGPDCAGCN VEYQPCNTNA
710 720 730 740 750
CPELKKTTPW TPWTPVNISD NGGHYEQRFR YTCKARLPDP NLLEVGRQRI
760 770 780 790 800
EMRYCSSDGT SGCSTDGLSG DFLRAGRYSA HTVNGAWSAW TSWSQCSRDC
810 820 830 840 850
SRGIRNRKRV CNNPEPKFGG MPCLGPSLEF QECNILPCPV DGVWSCWSSW
860 870 880 890 900
SKCSATCGGG HYMRTRSCSN PAPAYGGDIC LGLHTEEALC NTQTCPESWS
910 920 930 940 950
EWSDWSVCDA SGTQVRARQC ILLFPVGSQC SGNTTESRPC VFDSNFIPEV
960 970 980 990 1000
SVARSSSVEE KRCGEFNMFH MMAVGLSSSI LGCLLTLLVY TYCQRYQQQS
1010 1020 1030 1040 1050
HDATVIHPVS PAALNSSITN HINKLDKYDS VEAIKAFNKN NLILEERNKY
1060 1070
FNPHLTGKTY SNAYFTDLNN YDEY
Length:1,074
Mass (Da):120,321
Last modified:October 11, 2005 - v1
Checksum:i3A231A2E0D880C1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110236 Genomic DNA. No translation available.
AC113289 Genomic DNA. No translation available.
AC137123 Genomic DNA. No translation available.
AK141612 mRNA. Translation: BAE24765.1.
AK143026 mRNA. Translation: BAE25254.1.
CH466541 Genomic DNA. Translation: EDL08867.1.
RefSeqiNP_033180.2. NM_009154.2.
XP_006520106.1. XM_006520043.3.
XP_011243642.1. XM_011245340.1.
UniGeneiMm.260374.

Genome annotation databases

EnsembliENSMUST00000067458; ENSMUSP00000069024; ENSMUSG00000022231.
GeneIDi20356.
KEGGimmu:20356.
UCSCiuc007vku.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110236 Genomic DNA. No translation available.
AC113289 Genomic DNA. No translation available.
AC137123 Genomic DNA. No translation available.
AK141612 mRNA. Translation: BAE24765.1.
AK143026 mRNA. Translation: BAE25254.1.
CH466541 Genomic DNA. Translation: EDL08867.1.
RefSeqiNP_033180.2. NM_009154.2.
XP_006520106.1. XM_006520043.3.
XP_011243642.1. XM_011245340.1.
UniGeneiMm.260374.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069024.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000067458; ENSMUSP00000069024; ENSMUSG00000022231.
GeneIDi20356.
KEGGimmu:20356.
UCSCiuc007vku.1. mouse.

Organism-specific databases

CTDi9037.
MGIiMGI:107556. Sema5a.

Phylogenomic databases

eggNOGiKOG3611. Eukaryota.
ENOG410XQZC. LUCA.
GeneTreeiENSGT00760000119134.
HOVERGENiHBG062356.
KOiK06841.
OMAiLLVYTYC.
OrthoDBiEOG091G01T5.
TreeFamiTF329951.

Enzyme and pathway databases

ReactomeiR-MMU-416700. Other semaphorin interactions.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022231.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR016201. PSI.
IPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR000884. TSP1_rpt.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 4 hits.
PfamiPF01403. Sema. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view]
SMARTiSM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
SM00209. TSP1. 6 hits.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
SSF82895. SSF82895. 6 hits.
PROSITEiPS51004. SEMA. 1 hit.
PS50092. TSP1. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UPZ0_MOUSE
AccessioniPrimary (citable) accession number: Q3UPZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 30, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.