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Q3UPP9

- Q3UPP9_MOUSE

UniProt

Q3UPP9 - Q3UPP9_MOUSE

Protein

Oxytocin receptor

Gene

Oxtr

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.UniRule annotation

    GO - Molecular functioni

    1. oxytocin receptor activity Source: InterPro
    2. vasopressin receptor activity Source: InterPro

    GO - Biological processi

    1. positive regulation of blood pressure Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Oxytocin receptorUniRule annotation
    Gene namesi
    Name:OxtrImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:109147. Oxtr.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Keywords - PTMi

    GlycoproteinUniRule annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ3UPP9.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3UPP9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG105710.
    InParanoidiQ3UPP9.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR002062. Oxytocn_rcpt.
    IPR001817. Vasoprsn_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00665. OXYTOCINR.
    PR00896. VASOPRESSINR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3UPP9-1 [UniParc]FASTAAdd to Basket

    « Hide

    GSIELDLGSG VPPGAEGNLT AGPPRRNEAL ARVEVAVLCL ILFLALSGNA    50
    CVLLALRTTR HKHSRLFFFM KHLSIADLVV AVFQVLPQLL WDITFRFYGP 100
    DLLCRLVKYL QVVGMFASTY LLLVMSLDRC LAICQPLRSL RRRTDRLAVL 150
    ATWLGCLVAS VPQVHIFSLR EVADGVFDCW AVFIQPWGPK AYVTWITLAV 200
    YIVPVIVLAA CYGLISFKIW QNLRLKTAAA AAAAEGSDAA GGAGRAALAR 250
    VSSVKLISKA KIRTVKMTFI IVLAFIVCWT PFFFVQMWSV WDVNAPKEAS 300
    AFIIAMLLAS LNSCCNPWIY MLFTGHLFHE LVQRFLCCSA RYLKGSRPGE 350
    TSISKKSNSS TFVLSRRSSS QRSCSQPSSA 380
    Length:380
    Mass (Da):41,890
    Last modified:October 11, 2005 - v1
    Checksum:iA3863B9D77C78D32
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK143340 mRNA. Translation: BAE25346.1.
    UniGeneiMm.333310.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK143340 mRNA. Translation: BAE25346.1 .
    UniGenei Mm.333310.

    3D structure databases

    ProteinModelPortali Q3UPP9.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:109147. Oxtr.

    Phylogenomic databases

    HOVERGENi HBG105710.
    InParanoidi Q3UPP9.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3UPP9.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR002062. Oxytocn_rcpt.
    IPR001817. Vasoprsn_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00665. OXYTOCINR.
    PR00896. VASOPRESSINR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: OvaryImported.

    Entry informationi

    Entry nameiQ3UPP9_MOUSE
    AccessioniPrimary (citable) accession number: Q3UPP9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)