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Protein

Rab GDP dissociation inhibitor

Gene

Gdi2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Rab GDP dissociation inhibitorUniRule annotation
Gene namesi
Name:Gdi2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99845 Gdi2

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiQ3UPA3

Expressioni

Gene expression databases

GenevisibleiQ3UPA3 MM

Family & Domainsi

Sequence similaritiesi

Belongs to the Rab GDI family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1439 Eukaryota
COG5044 LUCA
HOGENOMiHOG000163825
HOVERGENiHBG000839
KOiK17255

Family and domain databases

Gene3Di3.50.50.603 hits
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR018203 GDP_dissociation_inhibitor
IPR000806 RabGDI
PANTHERiPTHR11787 PTHR11787, 1 hit
PfamiView protein in Pfam
PF00996 GDI, 1 hit
PRINTSiPR00892 RABGDI
PR00891 RABGDIREP
SUPFAMiSSF51905 SSF51905, 2 hits

Sequencei

Sequence statusi: Fragment.

Q3UPA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LSPPPLPPLP ALLFPLRWRP ASPPPQLRFS SPRFFPFPPT PGAQSGRTSR
60 70 80 90 100
SLLYGGLRAP ACAPFPAMNE EYDVIVLGTG LTECILSGIM SVNGKKVLHM
110 120 130 140 150
DQNPYYGGES ASITPLEDLY KRFKLPGQPP ASMGRGRDWN VDLIPKFLMA
160 170 180 190 200
NGQLVKMLLF TEVTRYMDFK VIEGSFVYKG GKIYKVPSTE AEALASSLMG
210 220 230 240 250
LFEKRRFRKF LVYVANFDEK DPRTFEGVDP KKTSMRDVYK KFDLGQDVID
260 270 280 290 300
FTGHSLALYR TDDYLDQPCC ETINRIKLYS ESLARYGKSP YLYPLYGLGE
310 320 330 340 350
LPQGFARLSA IYGGTYMLNK PIEEIIVQNG KVVGVKSEGE IARCKQLICD
360 370 380 390 400
PSYVKDRVEK VGQVIRVICI LSHPIKNTND ANSCQIIIPQ NQVNRKSDIY
410 420 430 440 450
VCMISFAHNV AAQGKYIAIV STTVETKEPE KEIRPALELL EPIEQKFVSI
460 470 480 490 500
SDLFVPKDLG TDSQIFISRA YDATTHFETT CDDIKDIYKR MTGSEFDFEE
510
MKRKKNDIYG ED
Length:512
Mass (Da):57,737
Last modified:October 11, 2005 - v1
Checksum:i0B8C0313C62ADE87
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK143681 mRNA Translation: BAE25494.1
RefSeqiNP_032138.3, NM_008112.4
UniGeneiMm.153226
Mm.221609

Genome annotation databases

GeneIDi14569
KEGGimmu:14569

Similar proteinsi

Entry informationi

Entry nameiQ3UPA3_MOUSE
AccessioniPrimary (citable) accession number: Q3UPA3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)