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Protein

Rab GDP dissociation inhibitor

Gene

Gdi2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Rab GDP dissociation inhibitorUniRule annotation
Gene namesi
Name:Gdi2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99845. Gdi2.

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ3UPA3.
PRIDEiQ3UPA3.

Expressioni

Gene expression databases

GenevisibleiQ3UPA3. MM.

Family & Domainsi

Sequence similaritiesi

Belongs to the Rab GDI family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1439. Eukaryota.
COG5044. LUCA.
HOGENOMiHOG000163825.
HOVERGENiHBG000839.
KOiK17255.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
InterProiView protein in InterPro
IPR023753. FAD/NAD-binding_dom.
IPR018203. GDP_dissociation_inhibitor.
IPR000806. RabGDI.
PANTHERiPTHR11787. PTHR11787. 1 hit.
PfamiView protein in Pfam
PF00996. GDI. 1 hit.
PRINTSiPR00892. RABGDI.
PR00891. RABGDIREP.
SUPFAMiSSF51905. SSF51905. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q3UPA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LSPPPLPPLP ALLFPLRWRP ASPPPQLRFS SPRFFPFPPT PGAQSGRTSR
60 70 80 90 100
SLLYGGLRAP ACAPFPAMNE EYDVIVLGTG LTECILSGIM SVNGKKVLHM
110 120 130 140 150
DQNPYYGGES ASITPLEDLY KRFKLPGQPP ASMGRGRDWN VDLIPKFLMA
160 170 180 190 200
NGQLVKMLLF TEVTRYMDFK VIEGSFVYKG GKIYKVPSTE AEALASSLMG
210 220 230 240 250
LFEKRRFRKF LVYVANFDEK DPRTFEGVDP KKTSMRDVYK KFDLGQDVID
260 270 280 290 300
FTGHSLALYR TDDYLDQPCC ETINRIKLYS ESLARYGKSP YLYPLYGLGE
310 320 330 340 350
LPQGFARLSA IYGGTYMLNK PIEEIIVQNG KVVGVKSEGE IARCKQLICD
360 370 380 390 400
PSYVKDRVEK VGQVIRVICI LSHPIKNTND ANSCQIIIPQ NQVNRKSDIY
410 420 430 440 450
VCMISFAHNV AAQGKYIAIV STTVETKEPE KEIRPALELL EPIEQKFVSI
460 470 480 490 500
SDLFVPKDLG TDSQIFISRA YDATTHFETT CDDIKDIYKR MTGSEFDFEE
510
MKRKKNDIYG ED
Length:512
Mass (Da):57,737
Last modified:October 11, 2005 - v1
Checksum:i0B8C0313C62ADE87
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK143681 mRNA. Translation: BAE25494.1.
RefSeqiNP_032138.3. NM_008112.4.
UniGeneiMm.153226.
Mm.221609.

Genome annotation databases

GeneIDi14569.
KEGGimmu:14569.

Similar proteinsi

Entry informationi

Entry nameiQ3UPA3_MOUSE
AccessioniPrimary (citable) accession number: Q3UPA3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)