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Protein
Submitted name:

Complement factor D (Adipsin), isoform CRA_c

Gene

Cfd

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Complement factor D (Adipsin), isoform CRA_cImported
Gene namesi
Name:CfdImported
Synonyms:AdnImported
ORF Names:mCG_13396Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87931 Cfd

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501430921421 – 259Sequence analysisAdd BLAST239

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiQ3UP47

Expressioni

Gene expression databases

BgeeiENSMUSG00000061780
ExpressionAtlasiQ3UP47 baseline and differential

Structurei

3D structure databases

SMRiQ3UP47
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 254Peptidase S1InterPro annotationAdd BLAST229

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
HOVERGENiHBG013304
KOiK01334
OMAiAHARPYM
OrthoDBiEOG091G0DF7

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR037561 Complement_factor_D
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PANTHERiPTHR43890:SF17 PTHR43890:SF17, 1 hit
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q3UP47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSSVYFVAL VILGAAVCAA QPRGRILGGQ EAAAHARPYM ASVQVNGTHV
60 70 80 90 100
CGGTLLDEQW VLSAAHCMDG VTDDDSVQVL LGAHSLSAPE PYKRWYDVQS
110 120 130 140 150
VVPHPGSRPD SLEDDLILFK LSQNASLGPH VRPLPLQYED KEVEPGTLCD
160 170 180 190 200
VAGWGVVTHA GRRPDVLHQL RVSIMNRTTC NLRTYHDGVV TINMMCAESN
210 220 230 240 250
RRDTCRGDSG SPLVCGDAVE GVVTWGSRVC GNGKKPGVYT RVSSYRMWIE

NITNGNMTS
Length:259
Mass (Da):28,057
Last modified:October 11, 2005 - v1
Checksum:i8C3A952561247DF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138778 mRNA Translation: AAI38779.1
BC138779 mRNA Translation: AAI38780.1
AK143817 mRNA Translation: BAE25550.1
CH466553 Genomic DNA Translation: EDL31634.1
RefSeqiNP_001316470.1, NM_001329541.1
NP_038487.1, NM_013459.4
UniGeneiMm.4407

Genome annotation databases

GeneIDi11537
KEGGimmu:11537

Similar proteinsi

Entry informationi

Entry nameiQ3UP47_MOUSE
AccessioniPrimary (citable) accession number: Q3UP47
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 20, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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