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Protein
Submitted name:

Uncharacterized protein

Gene

Gcgr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:GcgrImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99572. Gcgr.

Subcellular locationi

  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei148 – 167HelicalSequence analysisAdd BLAST20
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Transmembranei231 – 252HelicalSequence analysisAdd BLAST22
Transmembranei264 – 286HelicalSequence analysisAdd BLAST23
Transmembranei306 – 331HelicalSequence analysisAdd BLAST26
Transmembranei352 – 371HelicalSequence analysisAdd BLAST20
Transmembranei383 – 404HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500423008428 – 485Sequence analysisAdd BLAST458

Proteomic databases

PaxDbiQ3UN81.

Expressioni

Gene expression databases

GenevisibleiQ3UN81. MM.

Structurei

3D structure databases

ProteinModelPortaliQ3UN81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 126G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST84
Domaini142 – 405G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST264

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4564. Eukaryota.
ENOG410XRS2. LUCA.
HOVERGENiHBG008318.
KOiK04583.

Family and domain databases

Gene3Di4.10.1240.10. 1 hit.
InterProiView protein in InterPro
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003290. GPCR_2_GLP1/glucagon_rcpt.
IPR003291. GPCR_2_glucagon_rcpt.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
PRINTSiPR01353. GLUCAGNFAMLY.
PR01354. GLUCAGONR.
PR00249. GPCRSECRETIN.
SMARTiView protein in SMART
SM00008. HormR. 1 hit.
SUPFAMiSSF111418. SSF111418. 1 hit.
PROSITEiView protein in PROSITE
PS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UN81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLTQLHCPH LLLLLLVLSC LPEAPSAQVM DFLFEKWKLY SDQCHHNLSL
60 70 80 90 100
LPPPTELVCN RTFDKYSCWP DTPPNTTANI SCPWYLPWYH KVQHRLVFKR
110 120 130 140 150
CGPDGQWVRG PRGQPWRNAS QCQLDDEEIE VQKGVAKMYS SQQVMYTVGY
160 170 180 190 200
SLSLGALLLA LVILLGLRKL HCTRNYIHGN LFASFVLKAG SVLVIDWLLK
210 220 230 240 250
TRYSQKIGDD LSVSVWLSDG AMAGCRVATV IMQYGIIANY CWLLVEGVYL
260 270 280 290 300
YSLLSLATFS ERSFFSLYLG IGWGAPLLFV IPWVVVKCLF ENVQCWTSND
310 320 330 340 350
NMGFWWILRI PVFLALLINF FIFVHIIHLL VAKLRAHQMH YADYKFRLAR
360 370 380 390 400
STLTLIPLLG VHEVVFAFVT DEHAQGTLRS TKLFFDLFLS SFQGLLVAVL
410 420 430 440 450
YCFLNKEVQA ELMRRWRQWQ AGKALQEERL ASSHGSHMAP AGPCHGDPCE
460 470 480
KLQLMSAGSS SGTGCVPSME TSLASSLPRL ADSPT
Length:485
Mass (Da):54,871
Last modified:October 11, 2005 - v1
Checksum:i5148730D3441E67A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK144393 mRNA. Translation: BAE25866.1.
RefSeqiNP_032127.2. NM_008101.2.
UniGeneiMm.22329.

Genome annotation databases

GeneIDi14527.
KEGGimmu:14527.

Similar proteinsi

Entry informationi

Entry nameiQ3UN81_MOUSE
AccessioniPrimary (citable) accession number: Q3UN81
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)