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Protein
Submitted name:

Putative uncharacterized protein

Gene

Gcgr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:GcgrImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99572. Gcgr.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei148 – 167HelicalSequence analysisAdd BLAST20
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Transmembranei231 – 252HelicalSequence analysisAdd BLAST22
Transmembranei264 – 286HelicalSequence analysisAdd BLAST23
Transmembranei306 – 331HelicalSequence analysisAdd BLAST26
Transmembranei352 – 371HelicalSequence analysisAdd BLAST20
Transmembranei383 – 404HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500423008428 – 485Sequence analysisAdd BLAST458

Proteomic databases

PaxDbiQ3UN81.

Expressioni

Gene expression databases

GenevisibleiQ3UN81. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026119.

Structurei

3D structure databases

ProteinModelPortaliQ3UN81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 126G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST84
Domaini142 – 405G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST264

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4564. Eukaryota.
ENOG410XRS2. LUCA.
HOVERGENiHBG008318.
KOiK04583.

Family and domain databases

InterProiIPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003290. GPCR_2_GLP1/glucagon_rcpt.
IPR003291. GPCR_2_glucagon_rcpt.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
[Graphical view]
PRINTSiPR01353. GLUCAGNFAMLY.
PR01354. GLUCAGONR.
PR00249. GPCRSECRETIN.
SMARTiSM00008. HormR. 1 hit.
[Graphical view]
PROSITEiPS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UN81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLTQLHCPH LLLLLLVLSC LPEAPSAQVM DFLFEKWKLY SDQCHHNLSL
60 70 80 90 100
LPPPTELVCN RTFDKYSCWP DTPPNTTANI SCPWYLPWYH KVQHRLVFKR
110 120 130 140 150
CGPDGQWVRG PRGQPWRNAS QCQLDDEEIE VQKGVAKMYS SQQVMYTVGY
160 170 180 190 200
SLSLGALLLA LVILLGLRKL HCTRNYIHGN LFASFVLKAG SVLVIDWLLK
210 220 230 240 250
TRYSQKIGDD LSVSVWLSDG AMAGCRVATV IMQYGIIANY CWLLVEGVYL
260 270 280 290 300
YSLLSLATFS ERSFFSLYLG IGWGAPLLFV IPWVVVKCLF ENVQCWTSND
310 320 330 340 350
NMGFWWILRI PVFLALLINF FIFVHIIHLL VAKLRAHQMH YADYKFRLAR
360 370 380 390 400
STLTLIPLLG VHEVVFAFVT DEHAQGTLRS TKLFFDLFLS SFQGLLVAVL
410 420 430 440 450
YCFLNKEVQA ELMRRWRQWQ AGKALQEERL ASSHGSHMAP AGPCHGDPCE
460 470 480
KLQLMSAGSS SGTGCVPSME TSLASSLPRL ADSPT
Length:485
Mass (Da):54,871
Last modified:October 11, 2005 - v1
Checksum:i5148730D3441E67A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK144393 mRNA. Translation: BAE25866.1.
RefSeqiNP_032127.2. NM_008101.2.
UniGeneiMm.22329.

Genome annotation databases

GeneIDi14527.
KEGGimmu:14527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK144393 mRNA. Translation: BAE25866.1.
RefSeqiNP_032127.2. NM_008101.2.
UniGeneiMm.22329.

3D structure databases

ProteinModelPortaliQ3UN81.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026119.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ3UN81.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi14527.
KEGGimmu:14527.

Organism-specific databases

CTDi2642.
MGIiMGI:99572. Gcgr.

Phylogenomic databases

eggNOGiKOG4564. Eukaryota.
ENOG410XRS2. LUCA.
HOVERGENiHBG008318.
KOiK04583.

Miscellaneous databases

ChiTaRSiGcgr. mouse.
SOURCEiSearch...

Gene expression databases

GenevisibleiQ3UN81. MM.

Family and domain databases

InterProiIPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003290. GPCR_2_GLP1/glucagon_rcpt.
IPR003291. GPCR_2_glucagon_rcpt.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
[Graphical view]
PRINTSiPR01353. GLUCAGNFAMLY.
PR01354. GLUCAGONR.
PR00249. GPCRSECRETIN.
SMARTiSM00008. HormR. 1 hit.
[Graphical view]
PROSITEiPS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UN81_MOUSE
AccessioniPrimary (citable) accession number: Q3UN81
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 8, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.