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Protein
Submitted name:

Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_b

Gene

Mpp6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_bImported
Submitted name:
Mpp6 proteinImported
Gene namesi
Name:Mpp6Imported
ORF Names:mCG_119906Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1927340 Mpp6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000038388

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 48L27InterPro annotationAdd BLAST48
Domaini49 – 107L27InterPro annotationAdd BLAST59
Domaini129 – 208PDZInterPro annotationAdd BLAST80
Domaini228 – 297SH3InterPro annotationAdd BLAST70
Domaini351 – 538Guanylate kinase-likeInterPro annotationAdd BLAST188

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili523 – 543Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the MAGUK family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0609 Eukaryota
COG0194 LUCA
HOVERGENiHBG001858
OMAiDTIIPQQ
OrthoDBiEOG091G065I

Family and domain databases

CDDicd12038 SH3_MPP6, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR014775 L27_C
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR035603 MPP6_SH3
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF02828 L27, 2 hits
PF00595 PDZ, 1 hit
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00569 L27, 2 hits
SM00228 PDZ, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF101288 SSF101288, 1 hit
SSF50044 SSF50044, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS51022 L27, 2 hits
PS50106 PDZ, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

Q3UN60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQVLENLTE LPSSTGAEEI DLIFLKGIME NPIVKSLAKA HERLEDSKLE
60 70 80 90 100
AVSDNNLELV NEILEDITPL ISVDENVAEL VGILKEPHFQ SLLEAHDIVA
110 120 130 140 150
SKCYDSPPSS PEMNIPSLNN QLPVDAIRIL GIHKKAGEPL GVTFRVENND
160 170 180 190 200
LVIARILHGG MIDRQGLLHV GDIIKEVNGH EVGNNPKELQ ELLKNISGSV
210 220 230 240 250
TLKILPSYRD TITPQQSYVN MERHPAHVRQ VFVKCHFDYN PFNDNLIPCK
260 270 280 290 300
EAGLKFSKGE ILQIVNREDP NWWQASHVKE GGSAGLIPSQ FLEEKRKAFV
310 320 330 340 350
RRDWDNSGPF CGTISNKKKK KMMYLTTRNA EFDRHEIQIY EEVAKMPPFQ
360 370 380 390 400
RKTLVLIGAQ GVGRRSLKNR FIVLNPARFG TTVPFTSRKP REDEKDGQAY
410 420 430 440 450
KFVSRSEMEA DIKAGKYLEH GEYEGNLYGT KIDSILEVVQ TGRTCILDVN
460 470 480 490 500
PQALKVLRTS EFMPYVVFIA APELETLRAM HKAVVDAGIT TKLLTDSDLK
510 520 530 540 550
KTVDESARIQ RAYNHYFDLI IVNDNLDKAF EKLQTAIEKL RMEPQWVPIS

WVY
Length:553
Mass (Da):62,631
Last modified:October 11, 2005 - v1
Checksum:i26F3BE2445ABEDC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC145363 mRNA Translation: AAI45364.1
BC145364 mRNA Translation: AAI45365.1
AK144434 mRNA Translation: BAE25887.1
CH466597 Genomic DNA Translation: EDK98616.1
RefSeqiNP_001158205.1, NM_001164733.1
NP_001158206.1, NM_001164734.1
NP_064323.2, NM_019939.2
UniGeneiMm.248361
Mm.41288
Mm.463873

Genome annotation databases

GeneIDi56524
KEGGimmu:56524

Similar proteinsi

Entry informationi

Entry nameiQ3UN60_MOUSE
AccessioniPrimary (citable) accession number: Q3UN60
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health