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Q3UM29

- COG7_MOUSE

UniProt

Q3UM29 - COG7_MOUSE

Protein

Conserved oligomeric Golgi complex subunit 7

Gene

Cog7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    Required for normal Golgi function.By similarity

    GO - Biological processi

    1. intracellular protein transport Source: Ensembl
    2. protein glycosylation Source: Ensembl
    3. protein localization to Golgi apparatus Source: Ensembl
    4. protein stabilization Source: Ensembl
    5. retrograde vesicle-mediated transport, Golgi to ER Source: Ensembl

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Conserved oligomeric Golgi complex subunit 7
    Short name:
    COG complex subunit 7
    Alternative name(s):
    Component of oligomeric Golgi complex 7
    Gene namesi
    Name:Cog7
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:2685013. Cog7.

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi membrane Source: UniProtKB-SubCell
    2. Golgi transport complex Source: Ensembl

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 770770Conserved oligomeric Golgi complex subunit 7PRO_0000320147Add
    BLAST

    Proteomic databases

    MaxQBiQ3UM29.
    PaxDbiQ3UM29.
    PRIDEiQ3UM29.

    PTM databases

    PhosphoSiteiQ3UM29.

    Expressioni

    Gene expression databases

    BgeeiQ3UM29.
    CleanExiMM_COG7.
    GenevestigatoriQ3UM29.

    Interactioni

    Subunit structurei

    Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ3UM29.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the COG7 family.Curated

    Phylogenomic databases

    eggNOGiNOG288194.
    GeneTreeiENSGT00390000001260.
    HOGENOMiHOG000007766.
    HOVERGENiHBG020364.
    InParanoidiQ3UM29.
    OrthoDBiEOG78SQH8.
    PhylomeDBiQ3UM29.
    TreeFamiTF324498.

    Family and domain databases

    InterProiIPR019335. COG7.
    [Graphical view]
    PANTHERiPTHR21443. PTHR21443. 1 hit.
    PfamiPF10191. COG7. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3UM29-1 [UniParc]FASTAAdd to Basket

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    MDFSKFLADD FDVKDWINAA FRAGPKDGAA GKADGHAATL VMKLQLFIQE    50
    VNHAVEETSL QALQNMPKVL RDVEALKQEA SFLKEQMILV KEDIKKFEQD 100
    TSQSMQVLVE IDQVKSRMQL AAESLQEADK WSTLSADIEE TFKTQDIAVI 150
    SAKLTGMQNS LMMLVDTPDY SEKCVHLEAL KNRLEALASP QIVAAFTSQS 200
    VDQSKVFVKV FTEIDRMPQL LAYYYKCHKV QLLATWQELC QSDLPLDRQL 250
    TGLYDALLGA WHTQTQWATQ VFKNPHEVVT VLLIQTLGAL VPSLPMCLSA 300
    AVERAGPELE LTRLLEFYDT TAHFAKGLEM ALLPHLQDHN LVKVVELVDA 350
    VYGPYKPFQL KYGDMEENNL LIQISAVPLE HGEVIDCVQE LSHSVHKLFG 400
    LASAAVDRCA KFTNGLGTCG LLTALKSLFA KYVSHFTNAL QSIRKKCKLD 450
    DIPPNSLFQE DWTAFQNSVR IIATCGELLR QCGDFEQQLA NRILSTAGKY 500
    LSDSYSPRSL AGFQDSILTD KKSPAKNPWQ EYNYLQKDNP AEYASLMEIL 550
    YTLKEKGSSN HNLLSASRTA LTRLNQQAHQ LAFDSVFLRI KQQLLLVSRM 600
    DSWNTAGIGE TLTDDLPAFS LTPLEYISNI GQYIMSLPLN LEPFVTQEDS 650
    ALELALHAGK LPFPPEQGDE LPELDNMADN WLGSIARATM QTYCDVILQI 700
    PEVTPHSTKQ LATDIDYLIN VMDALGLQPS RTLQNIAALL KAKPEEYRQV 750
    SKGLPRRLAA TVATMRGVNY 770
    Length:770
    Mass (Da):86,073
    Last modified:October 11, 2005 - v1
    Checksum:i2DDE4F0E0923AB38
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti195 – 1951A → S in BAE32768. (PubMed:16141072)Curated
    Sequence conflicti301 – 3011A → G in BAE32768. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK145163 mRNA. Translation: BAE26269.1.
    AK154693 mRNA. Translation: BAE32768.1.
    CCDSiCCDS21805.1.
    RefSeqiNP_001028490.2. NM_001033318.3.
    UniGeneiMm.442015.

    Genome annotation databases

    EnsembliENSMUST00000057576; ENSMUSP00000058990; ENSMUSG00000034951.
    GeneIDi233824.
    KEGGimmu:233824.
    UCSCiuc009jnz.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK145163 mRNA. Translation: BAE26269.1 .
    AK154693 mRNA. Translation: BAE32768.1 .
    CCDSi CCDS21805.1.
    RefSeqi NP_001028490.2. NM_001033318.3.
    UniGenei Mm.442015.

    3D structure databases

    ProteinModelPortali Q3UM29.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q3UM29.

    Proteomic databases

    MaxQBi Q3UM29.
    PaxDbi Q3UM29.
    PRIDEi Q3UM29.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000057576 ; ENSMUSP00000058990 ; ENSMUSG00000034951 .
    GeneIDi 233824.
    KEGGi mmu:233824.
    UCSCi uc009jnz.1. mouse.

    Organism-specific databases

    CTDi 91949.
    MGIi MGI:2685013. Cog7.

    Phylogenomic databases

    eggNOGi NOG288194.
    GeneTreei ENSGT00390000001260.
    HOGENOMi HOG000007766.
    HOVERGENi HBG020364.
    InParanoidi Q3UM29.
    OrthoDBi EOG78SQH8.
    PhylomeDBi Q3UM29.
    TreeFami TF324498.

    Miscellaneous databases

    NextBioi 381863.
    PROi Q3UM29.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q3UM29.
    CleanExi MM_COG7.
    Genevestigatori Q3UM29.

    Family and domain databases

    InterProi IPR019335. COG7.
    [Graphical view ]
    PANTHERi PTHR21443. PTHR21443. 1 hit.
    Pfami PF10191. COG7. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: NOD.
      Tissue: Mammary gland.

    Entry informationi

    Entry nameiCOG7_MOUSE
    AccessioniPrimary (citable) accession number: Q3UM29
    Secondary accession number(s): Q3U3L7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3