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Protein
Submitted name:

Bone morphogenetic protein 4, isoform CRA_a

Gene

Bmp4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGrowth factorUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Bone morphogenetic protein 4, isoform CRA_aImported
Gene namesi
Name:Bmp4Imported
ORF Names:mCG_4634Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88180. Bmp4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501109889025 – 408Sequence analysisAdd BLAST384

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021835.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini289 – 408TGF_BETA_2InterPro annotationAdd BLAST120

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3900. Eukaryota.
ENOG410XT8Z. LUCA.
HOVERGENiHBG004860.
KOiK04662.
OMAiQGFHRIN.
OrthoDBiEOG091G0K7Z.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiView protein in InterPro
IPR029034. Cystine-knot_cytokine.
IPR001839. TGF-b_C.
IPR001111. TGF-b_propeptide.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiView protein in Pfam
PF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
SMARTiView protein in SMART
SM00204. TGFB. 1 hit.
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiView protein in PROSITE
PS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ULR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS
60 70 80 90 100
HELLRDFEAT LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEEQS
110 120 130 140 150
QGTGLEYPER PASRANTVRS FHHEEHLENI PGTSESSAFR FLFNLSSIPE
160 170 180 190 200
NEVISSAELR LFREQVDQGP DWEQGFHRIN IYEVMKPPAE MVPGHLITRL
210 220 230 240 250
LDTRLVHHNV TRWETFDVSP AVLRWTREKQ PNYGLAIEVT HLHQTRTHQG
260 270 280 290 300
QHVRISRSLP QGSGDWAQLR PLLVTFGHDG RGHTLTRRRA KRSPKHHPQR
310 320 330 340 350
SRKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN
360 370 380 390 400
STNHAIVQTL VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM

VVEGCGCR
Length:408
Mass (Da):46,497
Last modified:October 11, 2005 - v1
Checksum:i35053D844624EF9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK136527 mRNA. Translation: BAE23027.1.
AK145359 mRNA. Translation: BAE26387.1.
CH466605 Genomic DNA. Translation: EDL20710.1.
CH466605 Genomic DNA. Translation: EDL20712.1.
RefSeqiNP_001303289.1. NM_001316360.1.
NP_031580.2. NM_007554.3.
XP_006518530.1. XM_006518467.3.
XP_006518531.1. XM_006518468.3.
XP_011243236.1. XM_011244934.2.
XP_011243237.1. XM_011244935.2.
UniGeneiMm.6813.

Genome annotation databases

GeneIDi12159.
KEGGimmu:12159.

Similar proteinsi

Entry informationi

Entry nameiQ3ULR1_MOUSE
AccessioniPrimary (citable) accession number: Q3ULR1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)