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Protein
Submitted name:

Protein inhibitor of activated STAT 4

Gene

Pias4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri304 – 381SP-RING-typePROSITE-ProRule annotationAdd BLAST78

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Protein inhibitor of activated STAT 4Imported
Gene namesi
Name:Pias4Imported
ORF Names:mCG_12131Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2136940. Pias4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000004934.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3ULQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 46SAPInterPro annotationAdd BLAST35
Domaini112 – 272PINITInterPro annotationAdd BLAST161
Domaini304 – 381SP-RING-typeInterPro annotationAdd BLAST78

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri304 – 381SP-RING-typePROSITE-ProRule annotationAdd BLAST78

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2169. Eukaryota.
ENOG410XQ2E. LUCA.
HOVERGENiHBG053598.
KOiK16065.
OMAiLRICYTD.
OrthoDBiEOG091G08G5.

Family and domain databases

Gene3Di1.10.720.30. 1 hit.
InterProiView protein in InterPro
IPR027224. PIAS4.
IPR023321. PINIT.
IPR003034. SAP_dom.
IPR036361. SAP_dom_sf.
IPR004181. Znf_MIZ.
PANTHERiPTHR10782:SF9. PTHR10782:SF9. 1 hit.
PfamiView protein in Pfam
PF14324. PINIT. 1 hit.
PF02891. zf-MIZ. 1 hit.
SMARTiView protein in SMART
SM00513. SAP. 1 hit.
SUPFAMiSSF68906. SSF68906. 1 hit.
PROSITEiView protein in PROSITE
PS51466. PINIT. 1 hit.
PS50800. SAP. 1 hit.
PS51044. ZF_SP_RING. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ULQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC
60 70 80 90 100
SPELFKKIKE LYETRYAKKS AEPGPQAPRP LDPLALHSMP RTPLSGPTVD
110 120 130 140 150
YPVLYGKYLN GLGRLPTKTL KPEVRLVKLP FFNMLDELLK PTELVPQSAE
160 170 180 190 200
KLQESPCIFA LTPRQVEMIR NSRELQPGVK AVQVVLRICY SDTSCPQEDQ
210 220 230 240 250
YPPNIAVKVN HSYCSVPGYY PSNKPGVEPK RPCRPINLTH LMYLSSATNR
260 270 280 290 300
ITVTWGNYGK SYSVALYLVR QLTSSDLLQR LKTIGVKHPE LCKALVKEKL
310 320 330 340 350
RLDPDSEIAT TGVRVSLICP LVKMRLSVPC RAETCAHLQC FDAVFYLQMN
360 370 380 390 400
EKKPTWMCPV CDKPAAYDQL IIDGLLSKIL SECEGADEIE FLAEGSWRPI
410 420 430 440 450
RAEKEPSCSP QGPILVLGTS DANGLAPASS TPGIGSGLSG PGSAGSGAGA
460 470 480 490 500
AGSLENGKTG ADVVDLTLDS SSSSEDEDED EDDDEDEDEG PRPKRRCPFQ

KGLVPAC
Length:507
Mass (Da):55,570
Last modified:October 11, 2005 - v1
Checksum:iA8E5E6E3BAC76426
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK145367 mRNA. Translation: BAE26392.1.
CH466553 Genomic DNA. Translation: EDL31454.1.
RefSeqiNP_067476.2. NM_021501.4.
UniGeneiMm.34428.

Genome annotation databases

GeneIDi59004.
KEGGimmu:59004.

Similar proteinsi

Entry informationi

Entry nameiQ3ULQ6_MOUSE
AccessioniPrimary (citable) accession number: Q3ULQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)