Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q3ULN5

- Q3ULN5_MOUSE

UniProt

Q3ULN5 - Q3ULN5_MOUSE

Protein

Peptidyl-prolyl cis-trans isomerase

Gene

Fkbp1a

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. calcium channel inhibitor activity Source: RefGenome
    2. drug binding Source: MGI
    3. FK506 binding Source: MGI
    4. peptidyl-prolyl cis-trans isomerase activity Source: RefGenome
    5. protein binding Source: MGI
    6. protein homodimerization activity Source: MGI

    GO - Biological processi

    1. chaperone-mediated protein folding Source: RefGenome
    2. cytokine-mediated signaling pathway Source: MGI
    3. muscle contraction Source: MGI
    4. negative regulation of protein phosphorylation Source: MGI
    5. negative regulation of release of sequestered calcium ion into cytosol Source: RefGenome
    6. protein peptidyl-prolyl isomerization Source: RefGenome
    7. release of sequestered calcium ion into cytosol Source: MGI
    8. response to caffeine Source: MGI
    9. T cell proliferation Source: MGI

    Keywords - Molecular functioni

    Isomerase, RotamaseUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptidyl-prolyl cis-trans isomeraseUniRule annotation
    Gene namesi
    Name:Fkbp1aImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:95541. Fkbp1a.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: MGI
    2. sarcoplasmic reticulum membrane Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3ULN5.

    Expressioni

    Gene expression databases

    GenevestigatoriQ3ULN5.

    Interactioni

    Protein-protein interaction databases

    IntActiQ3ULN5. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3ULN5.
    SMRiQ3ULN5. Positions 2-108.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PPIase FKBP-type domain.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG051623.

    Family and domain databases

    InterProiIPR023566. PPIase_FKBP.
    IPR001179. PPIase_FKBP_dom.
    [Graphical view]
    PANTHERiPTHR10516. PTHR10516. 1 hit.
    PfamiPF00254. FKBP_C. 1 hit.
    [Graphical view]
    PROSITEiPS50059. FKBP_PPIASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3ULN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGVQVETISP GDGRTFPKRG QTCVVHYTWM LEDGKKFDSS RDRNKPFKFT    50
    LGKQEVIRGW EEGVAQMSVG QRAKLIISSD YAYGATGHPG IIPPHATLVF 100
    DVELLKLE 108
    Length:108
    Mass (Da):12,052
    Last modified:October 11, 2005 - v1
    Checksum:iE691437F373F6993
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK145400 mRNA. Translation: BAE26413.1.
    UniGeneiMm.278458.
    Mm.487732.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK145400 mRNA. Translation: BAE26413.1 .
    UniGenei Mm.278458.
    Mm.487732.

    3D structure databases

    ProteinModelPortali Q3ULN5.
    SMRi Q3ULN5. Positions 2-108.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q3ULN5. 1 interaction.

    Proteomic databases

    PRIDEi Q3ULN5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:95541. Fkbp1a.

    Phylogenomic databases

    HOVERGENi HBG051623.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3ULN5.

    Family and domain databases

    InterProi IPR023566. PPIase_FKBP.
    IPR001179. PPIase_FKBP_dom.
    [Graphical view ]
    PANTHERi PTHR10516. PTHR10516. 1 hit.
    Pfami PF00254. FKBP_C. 1 hit.
    [Graphical view ]
    PROSITEi PS50059. FKBP_PPIASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.

    Entry informationi

    Entry nameiQ3ULN5_MOUSE
    AccessioniPrimary (citable) accession number: Q3ULN5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)