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Protein
Submitted name:

UPF3 regulator of nonsense transcripts homolog B (yeast)

Gene

Upf3b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-109688 Cleavage of Growing Transcript in the Termination Region
R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-72163 mRNA Splicing - Major Pathway
R-MMU-72187 mRNA 3'-end processing
R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Submitted name:
UPF3 regulator of nonsense transcripts homolog B (yeast)Imported
Gene namesi
Name:Upf3bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1915384 Upf3b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ3ULL6
PeptideAtlasiQ3ULL6

Expressioni

Gene expression databases

BgeeiENSMUSG00000036572

Interactioni

Protein-protein interaction databases

IntActiQ3ULL6 1 interactor.
STRINGi10090.ENSMUSP00000075614

Structurei

3D structure databases

SMRiQ3ULL6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 208Smg4_UPF3InterPro annotationAdd BLAST159

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili200 – 253Sequence analysisAdd BLAST54
Coiled coili336 – 399Sequence analysisAdd BLAST64

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1295 Eukaryota
ENOG41122XD LUCA
GeneTreeiENSGT00390000017146
HOGENOMiHOG000230909
HOVERGENiHBG059714
KOiK14328
OMAiQDPEFMA
OrthoDBiEOG091G0JKF
TreeFamiTF316034

Family and domain databases

CDDicd12728 RRM_like_Smg4_UPF3B, 1 hit
Gene3Di3.30.70.3301 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR005120 UPF3_dom
IPR034979 UPF3B_RRM-like
PfamiView protein in Pfam
PF03467 Smg4_UPF3, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit

Sequencei

Sequence statusi: Complete.

Q3ULL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEEKDHRPK EKRVTLFTPQ GATGGCIGAT AEGAKGDDRQ DRNRDKKEAL
60 70 80 90 100
SKVVIRRLPP TLTKEQLQEH LQPMPEHDYF EFFSNDTSLY PHMYARAYIN
110 120 130 140 150
FKNQEDILLF RDRFDGYVFL DNKGQEYHAI VEFAPFQKAA KKKIKKRDTK
160 170 180 190 200
VGTIEDDPEY RKFLESYATD NEKMTSTPET LLEEIEAKNR ELIAKRTTPL
210 220 230 240 250
LSFLKNKQRM REEKREERRR REIERKRQRE EERRKWKEEE KRKRKDIEKL
260 270 280 290 300
KKIERIPERE KIRDEPKIKL LRKPEKGDEK ELDKRDKTKR LDKENLNEER
310 320 330 340 350
ASGHSYTLPR RSDVELKDEK PKRLDDEGVR DYRDRDRDYE RDQERMIRER
360 370 380 390 400
ERLKRQEEER RRQQQKERYE KEKAFKRKEE EMKREKEALR DKGKKSENTE
410 420 430 440 450
SICSLEKIEK KEEVVKRDRI RNKDRPAMQL YQPGARSRSR LCPADDSIKP
460 470
GDSPVDKKQE SGISHRKEGG EE
Length:472
Mass (Da):57,065
Last modified:October 11, 2005 - v1
Checksum:i352BB365348FB7DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL451076 Genomic DNA No translation available.
AK145431 mRNA Translation: BAE26432.1
RefSeqiNP_080849.1, NM_026573.3
UniGeneiMm.271160

Genome annotation databases

EnsembliENSMUST00000076265; ENSMUSP00000075614; ENSMUSG00000036572
GeneIDi68134
KEGGimmu:68134
UCSCiuc009sye.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ3ULL6_MOUSE
AccessioniPrimary (citable) accession number: Q3ULL6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 25, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported