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Q3UKR0

- Q3UKR0_MOUSE

UniProt

Q3UKR0 - Q3UKR0_MOUSE

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Protein
Submitted name:

Death domain-associated protein 6

Gene

Daxx

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein kinase activator activity Source: Ensembl
  2. transcription corepressor activity Source: Ensembl

GO - Biological processi

  1. androgen receptor signaling pathway Source: Ensembl
  2. apoptotic signaling pathway Source: MGI
  3. chromatin remodeling Source: Ensembl
  4. mitotic cytokinesis Source: MGI
  5. negative regulation of transcription, DNA-templated Source: MGI
  6. nucleosome assembly Source: Ensembl
  7. positive regulation of apoptotic signaling pathway Source: MGI
  8. positive regulation of neuron death Source: Ensembl
  9. regulation of protein ubiquitination Source: Ensembl
  10. regulation of transcription, DNA-templated Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Death domain-associated protein 6Imported
Submitted name:
Fas death domain-associated proteinImported
Gene namesi
Name:DaxxImported
ORF Names:mCG_22998Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:1197015. Daxx.

Subcellular locationi

GO - Cellular componenti

  1. heterochromatin Source: MGI
  2. nucleus Source: MGI
  3. PML body Source: MGI
  4. SWI/SNF superfamily-type complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ3UKR0.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000009448.
HOVERGENiHBG031495.
KOiK02308.
OMAiELCKTQT.
TreeFamiTF325803.

Family and domain databases

InterProiIPR005012. Daxx.
[Graphical view]
PANTHERiPTHR12766. PTHR12766. 1 hit.
PfamiPF03344. Daxx. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UKR0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATDDSIIVL DDDDEDEAAA QPGPSNLPPN PASTGPGPGL SQQATGLSEP
60 70 80 90 100
RVDGGSSNSG SRKCYKLDNE KLFEEFLELC KTETSDHPEV VPFLHKLQQR
110 120 130 140 150
AQSVFLASAE FCNILSRVLA RSRKRPAKIY VYINELCTVL KAHSIKKKLN
160 170 180 190 200
LAPAASTTSE ASGPNPPTEP PSDLTNTENT ASEASRTRGS RRQIQRLEQL
210 220 230 240 250
LALYVAEIRR LQEKELDLSE LDDPDSSYLQ EARLKRKLIR LFGRLCELKD
260 270 280 290 300
CSSLTGRVIE QRIPYRGTRY PEVNRRIERL INKPGLDTFP DYGDVLRAVE
310 320 330 340 350
KAATRHSLGL PRQQLQLLAQ DAFRDVGVRL QERRHLDLIY NFGCHLTDDY
360 370 380 390 400
RPGVDPALSD PTLARRLREN RTLAMNRLDE VISKYAMMQD KTEEGERQKR
410 420 430 440 450
RARLLGTAPQ PSDPPKASSE SGEGPSGMAS QECPTTSKAE TDDDDDDDDD
460 470 480 490 500
DDDEDNEESE EEEEEEEEEK EATEDEDEDL EQLQEDQGGD EEEEGGDNEG
510 520 530 540 550
NESPTSPSDF FHRRNSEPAE GLRTPEGQQK RGLTETPASP PGASLDPPST
560 570 580 590 600
DAESSGEQLL EPLLGDESPV SQLAELEMEA LPEERDISSS RKKSEDSLPT
610 620 630 640 650
ILENGAAVVT STSVNGRVSS HTWRDASPPS KRFRKEKKQL GSGLLGNSYI
660 670 680 690 700
KEPMAQQDSG QNTSVQPMPS PPLASVASVA DSSTRVDSPS HELVTSSLCS
710 720 730 740
PSPSLLLQTP QAQSLRQCIY KTSVATQCDP EEIIVLSDSD
Length:740
Mass (Da):81,594
Last modified:October 11, 2005 - v1
Checksum:i4965BFA754D88D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974462 Genomic DNA. No translation available.
AK133863 mRNA. Translation: BAE21895.1.
AK145906 mRNA. Translation: BAE26741.1.
AK153149 mRNA. Translation: BAE31759.1.
CH466660 Genomic DNA. Translation: EDL10223.1.
RefSeqiNP_001186662.1. NM_001199733.1.
NP_031855.3. NM_007829.4.
XP_006523643.1. XM_006523580.1.
XP_006523644.1. XM_006523581.1.
XP_006523645.1. XM_006523582.1.
XP_006525362.1. XM_006525299.1.
XP_006525363.1. XM_006525300.1.
XP_006525364.1. XM_006525301.1.
UniGeneiMm.271809.

Genome annotation databases

EnsembliENSMUST00000079421; ENSMUSP00000078390; ENSMUSG00000002307.
ENSMUST00000170075; ENSMUSP00000128504; ENSMUSG00000002307.
ENSMUST00000174146; ENSMUSP00000134158; ENSMUSG00000002307.
GeneIDi13163.
KEGGimmu:13163.
UCSCiuc008caa.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974462 Genomic DNA. No translation available.
AK133863 mRNA. Translation: BAE21895.1 .
AK145906 mRNA. Translation: BAE26741.1 .
AK153149 mRNA. Translation: BAE31759.1 .
CH466660 Genomic DNA. Translation: EDL10223.1 .
RefSeqi NP_001186662.1. NM_001199733.1.
NP_031855.3. NM_007829.4.
XP_006523643.1. XM_006523580.1.
XP_006523644.1. XM_006523581.1.
XP_006523645.1. XM_006523582.1.
XP_006525362.1. XM_006525299.1.
XP_006525363.1. XM_006525300.1.
XP_006525364.1. XM_006525301.1.
UniGenei Mm.271809.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000079421 ; ENSMUSP00000078390 ; ENSMUSG00000002307 .
ENSMUST00000170075 ; ENSMUSP00000128504 ; ENSMUSG00000002307 .
ENSMUST00000174146 ; ENSMUSP00000134158 ; ENSMUSG00000002307 .
GeneIDi 13163.
KEGGi mmu:13163.
UCSCi uc008caa.2. mouse.

Organism-specific databases

CTDi 1616.
MGIi MGI:1197015. Daxx.

Phylogenomic databases

GeneTreei ENSGT00390000009448.
HOVERGENi HBG031495.
KOi K02308.
OMAi ELCKTQT.
TreeFami TF325803.

Miscellaneous databases

NextBioi 283238.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3UKR0.

Family and domain databases

InterProi IPR005012. Daxx.
[Graphical view ]
PANTHERi PTHR12766. PTHR12766. 1 hit.
Pfami PF03344. Daxx. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
  10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  12. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3UKR0_MOUSE
AccessioniPrimary (citable) accession number: Q3UKR0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 26, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3