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Protein
Submitted name:

Death domain-associated protein 6

Gene

Daxx

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-6804757. Regulation of TP53 Degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Death domain-associated protein 6Imported
Submitted name:
Fas death domain-associated proteinImported
Gene namesi
Name:DaxxImported
ORF Names:mCG_22998Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1197015. Daxx.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000002307.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078390.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 151DaxxInterPro annotationAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili449 – 486Sequence analysisAdd BLAST38

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IGIP. Eukaryota.
ENOG4111K0B. LUCA.
GeneTreeiENSGT00390000009448.
HOVERGENiHBG031495.
KOiK02308.
OMAiLCKTQTA.
OrthoDBiEOG091G0JSL.
TreeFamiTF325803.

Family and domain databases

CDDicd13151. DAXX_helical_bundle. 1 hit.
InterProiIPR005012. Daxx.
IPR031333. Daxx_N.
[Graphical view]
PANTHERiPTHR12766. PTHR12766. 1 hit.
PfamiPF03344. Daxx. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UKR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATDDSIIVL DDDDEDEAAA QPGPSNLPPN PASTGPGPGL SQQATGLSEP
60 70 80 90 100
RVDGGSSNSG SRKCYKLDNE KLFEEFLELC KTETSDHPEV VPFLHKLQQR
110 120 130 140 150
AQSVFLASAE FCNILSRVLA RSRKRPAKIY VYINELCTVL KAHSIKKKLN
160 170 180 190 200
LAPAASTTSE ASGPNPPTEP PSDLTNTENT ASEASRTRGS RRQIQRLEQL
210 220 230 240 250
LALYVAEIRR LQEKELDLSE LDDPDSSYLQ EARLKRKLIR LFGRLCELKD
260 270 280 290 300
CSSLTGRVIE QRIPYRGTRY PEVNRRIERL INKPGLDTFP DYGDVLRAVE
310 320 330 340 350
KAATRHSLGL PRQQLQLLAQ DAFRDVGVRL QERRHLDLIY NFGCHLTDDY
360 370 380 390 400
RPGVDPALSD PTLARRLREN RTLAMNRLDE VISKYAMMQD KTEEGERQKR
410 420 430 440 450
RARLLGTAPQ PSDPPKASSE SGEGPSGMAS QECPTTSKAE TDDDDDDDDD
460 470 480 490 500
DDDEDNEESE EEEEEEEEEK EATEDEDEDL EQLQEDQGGD EEEEGGDNEG
510 520 530 540 550
NESPTSPSDF FHRRNSEPAE GLRTPEGQQK RGLTETPASP PGASLDPPST
560 570 580 590 600
DAESSGEQLL EPLLGDESPV SQLAELEMEA LPEERDISSS RKKSEDSLPT
610 620 630 640 650
ILENGAAVVT STSVNGRVSS HTWRDASPPS KRFRKEKKQL GSGLLGNSYI
660 670 680 690 700
KEPMAQQDSG QNTSVQPMPS PPLASVASVA DSSTRVDSPS HELVTSSLCS
710 720 730 740
PSPSLLLQTP QAQSLRQCIY KTSVATQCDP EEIIVLSDSD
Length:740
Mass (Da):81,594
Last modified:October 11, 2005 - v1
Checksum:i4965BFA754D88D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974462 Genomic DNA. No translation available.
AK133863 mRNA. Translation: BAE21895.1.
AK145906 mRNA. Translation: BAE26741.1.
AK153149 mRNA. Translation: BAE31759.1.
CH466660 Genomic DNA. Translation: EDL10223.1.
RefSeqiNP_001186662.1. NM_001199733.1.
NP_031855.3. NM_007829.4.
XP_006523643.1. XM_006523580.2.
XP_006523644.1. XM_006523581.2.
XP_006523645.1. XM_006523582.2.
UniGeneiMm.271809.

Genome annotation databases

EnsembliENSMUST00000079421; ENSMUSP00000078390; ENSMUSG00000002307.
ENSMUST00000170075; ENSMUSP00000128504; ENSMUSG00000002307.
ENSMUST00000174146; ENSMUSP00000134158; ENSMUSG00000002307.
GeneIDi13163.
KEGGimmu:13163.
UCSCiuc008caa.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974462 Genomic DNA. No translation available.
AK133863 mRNA. Translation: BAE21895.1.
AK145906 mRNA. Translation: BAE26741.1.
AK153149 mRNA. Translation: BAE31759.1.
CH466660 Genomic DNA. Translation: EDL10223.1.
RefSeqiNP_001186662.1. NM_001199733.1.
NP_031855.3. NM_007829.4.
XP_006523643.1. XM_006523580.2.
XP_006523644.1. XM_006523581.2.
XP_006523645.1. XM_006523582.2.
UniGeneiMm.271809.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078390.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000079421; ENSMUSP00000078390; ENSMUSG00000002307.
ENSMUST00000170075; ENSMUSP00000128504; ENSMUSG00000002307.
ENSMUST00000174146; ENSMUSP00000134158; ENSMUSG00000002307.
GeneIDi13163.
KEGGimmu:13163.
UCSCiuc008caa.2. mouse.

Organism-specific databases

CTDi1616.
MGIiMGI:1197015. Daxx.

Phylogenomic databases

eggNOGiENOG410IGIP. Eukaryota.
ENOG4111K0B. LUCA.
GeneTreeiENSGT00390000009448.
HOVERGENiHBG031495.
KOiK02308.
OMAiLCKTQTA.
OrthoDBiEOG091G0JSL.
TreeFamiTF325803.

Enzyme and pathway databases

ReactomeiR-MMU-6804757. Regulation of TP53 Degradation.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000002307.

Family and domain databases

CDDicd13151. DAXX_helical_bundle. 1 hit.
InterProiIPR005012. Daxx.
IPR031333. Daxx_N.
[Graphical view]
PANTHERiPTHR12766. PTHR12766. 1 hit.
PfamiPF03344. Daxx. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UKR0_MOUSE
AccessioniPrimary (citable) accession number: Q3UKR0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 2, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.