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Q3UKR0

- Q3UKR0_MOUSE

UniProt

Q3UKR0 - Q3UKR0_MOUSE

Protein
Submitted name:

Death domain-associated protein 6

Gene

Daxx

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. androgen receptor signaling pathway Source: Ensembl
    2. apoptotic signaling pathway Source: MGI
    3. mitotic cytokinesis Source: MGI
    4. negative regulation of transcription, DNA-templated Source: MGI
    5. positive regulation of apoptotic signaling pathway Source: MGI
    6. regulation of protein ubiquitination Source: Ensembl
    7. regulation of transcription, DNA-templated Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Death domain-associated protein 6Imported
    Submitted name:
    Fas death domain-associated proteinImported
    Gene namesi
    Name:DaxxImported
    ORF Names:mCG_22998Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1197015. Daxx.

    Subcellular locationi

    GO - Cellular componenti

    1. heterochromatin Source: MGI
    2. nucleus Source: MGI
    3. PML body Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ3UKR0.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000009448.
    HOVERGENiHBG031495.
    InParanoidiQ3UKR0.
    KOiK02308.
    OMAiELCKTQT.
    TreeFamiTF325803.

    Family and domain databases

    InterProiIPR005012. Daxx.
    [Graphical view]
    PANTHERiPTHR12766. PTHR12766. 1 hit.
    PfamiPF03344. Daxx. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3UKR0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATDDSIIVL DDDDEDEAAA QPGPSNLPPN PASTGPGPGL SQQATGLSEP    50
    RVDGGSSNSG SRKCYKLDNE KLFEEFLELC KTETSDHPEV VPFLHKLQQR 100
    AQSVFLASAE FCNILSRVLA RSRKRPAKIY VYINELCTVL KAHSIKKKLN 150
    LAPAASTTSE ASGPNPPTEP PSDLTNTENT ASEASRTRGS RRQIQRLEQL 200
    LALYVAEIRR LQEKELDLSE LDDPDSSYLQ EARLKRKLIR LFGRLCELKD 250
    CSSLTGRVIE QRIPYRGTRY PEVNRRIERL INKPGLDTFP DYGDVLRAVE 300
    KAATRHSLGL PRQQLQLLAQ DAFRDVGVRL QERRHLDLIY NFGCHLTDDY 350
    RPGVDPALSD PTLARRLREN RTLAMNRLDE VISKYAMMQD KTEEGERQKR 400
    RARLLGTAPQ PSDPPKASSE SGEGPSGMAS QECPTTSKAE TDDDDDDDDD 450
    DDDEDNEESE EEEEEEEEEK EATEDEDEDL EQLQEDQGGD EEEEGGDNEG 500
    NESPTSPSDF FHRRNSEPAE GLRTPEGQQK RGLTETPASP PGASLDPPST 550
    DAESSGEQLL EPLLGDESPV SQLAELEMEA LPEERDISSS RKKSEDSLPT 600
    ILENGAAVVT STSVNGRVSS HTWRDASPPS KRFRKEKKQL GSGLLGNSYI 650
    KEPMAQQDSG QNTSVQPMPS PPLASVASVA DSSTRVDSPS HELVTSSLCS 700
    PSPSLLLQTP QAQSLRQCIY KTSVATQCDP EEIIVLSDSD 740
    Length:740
    Mass (Da):81,594
    Last modified:October 11, 2005 - v1
    Checksum:i4965BFA754D88D85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR974462 Genomic DNA. No translation available.
    AK133863 mRNA. Translation: BAE21895.1.
    AK145906 mRNA. Translation: BAE26741.1.
    AK153149 mRNA. Translation: BAE31759.1.
    CH466660 Genomic DNA. Translation: EDL10223.1.
    RefSeqiNP_001186662.1. NM_001199733.1.
    NP_031855.3. NM_007829.4.
    XP_006523643.1. XM_006523580.1.
    XP_006523644.1. XM_006523581.1.
    XP_006523645.1. XM_006523582.1.
    XP_006525362.1. XM_006525299.1.
    XP_006525363.1. XM_006525300.1.
    XP_006525364.1. XM_006525301.1.
    UniGeneiMm.271809.

    Genome annotation databases

    EnsembliENSMUST00000079421; ENSMUSP00000078390; ENSMUSG00000002307.
    ENSMUST00000170075; ENSMUSP00000128504; ENSMUSG00000002307.
    ENSMUST00000174146; ENSMUSP00000134158; ENSMUSG00000002307.
    GeneIDi13163.
    KEGGimmu:13163.
    UCSCiuc008caa.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR974462 Genomic DNA. No translation available.
    AK133863 mRNA. Translation: BAE21895.1 .
    AK145906 mRNA. Translation: BAE26741.1 .
    AK153149 mRNA. Translation: BAE31759.1 .
    CH466660 Genomic DNA. Translation: EDL10223.1 .
    RefSeqi NP_001186662.1. NM_001199733.1.
    NP_031855.3. NM_007829.4.
    XP_006523643.1. XM_006523580.1.
    XP_006523644.1. XM_006523581.1.
    XP_006523645.1. XM_006523582.1.
    XP_006525362.1. XM_006525299.1.
    XP_006525363.1. XM_006525300.1.
    XP_006525364.1. XM_006525301.1.
    UniGenei Mm.271809.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000079421 ; ENSMUSP00000078390 ; ENSMUSG00000002307 .
    ENSMUST00000170075 ; ENSMUSP00000128504 ; ENSMUSG00000002307 .
    ENSMUST00000174146 ; ENSMUSP00000134158 ; ENSMUSG00000002307 .
    GeneIDi 13163.
    KEGGi mmu:13163.
    UCSCi uc008caa.2. mouse.

    Organism-specific databases

    CTDi 1616.
    MGIi MGI:1197015. Daxx.

    Phylogenomic databases

    GeneTreei ENSGT00390000009448.
    HOVERGENi HBG031495.
    InParanoidi Q3UKR0.
    KOi K02308.
    OMAi ELCKTQT.
    TreeFami TF325803.

    Miscellaneous databases

    NextBioi 283238.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3UKR0.

    Family and domain databases

    InterProi IPR005012. Daxx.
    [Graphical view ]
    PANTHERi PTHR12766. PTHR12766. 1 hit.
    Pfami PF03344. Daxx. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    7. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    8. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported, PlacentaImported and Whole bodyImported.
    10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    12. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ3UKR0_MOUSE
    AccessioniPrimary (citable) accession number: Q3UKR0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3