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Protein
Submitted name:

Interferon dependent positive acting transcription factor 3 gamma, isoform CRA_c

Gene

Irf9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon dependent positive acting transcription factor 3 gamma, isoform CRA_cImported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Irf9Imported
Synonyms:Isgf3gImported
ORF Names:mCG_22052Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107587. Irf9.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000002325.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000120525.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 116IRF tryptophan pentad repeat DNA-bindingInterPro annotationAdd BLAST108

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IECM. Eukaryota.
ENOG4111AEC. LUCA.
HOGENOMiHOG000010107.
HOVERGENiHBG003072.
KOiK04693.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.200.10. 1 hit.
InterProiView protein in InterPro
IPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR019471. Interferon_reg_factor-3.
IPR017855. SMAD_dom-like.
IPR008984. SMAD_FHA_domain.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11949. PTHR11949. 1 hit.
PfamiView protein in Pfam
PF00605. IRF. 1 hit.
PF10401. IRF-3. 1 hit.
PRINTSiPR00267. INTFRNREGFCT.
SMARTiView protein in SMART
SM00348. IRF. 1 hit.
SM01243. IRF-3. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF49879. SSF49879. 1 hit.
PROSITEiView protein in PROSITE
PS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UKQ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGKVRCTR KLRSWIVEQV ESGHFPGVCW DDAAKTMFRI PWKHAGKQDF
60 70 80 90 100
REDQDAAIFK AWALFKEKHK DGDIGHPAVW KTRLRCALNK SSEFEEVPER
110 120 130 140 150
GRMDVAEPYK VYRILPAGTL PNQPRNQKSP CKRSISCVSP EREENMENGR
160 170 180 190 200
TNGVVNHSDS GSNIGGGGNG SNRSDSNSNC NSELEEGAGT TEATIREDPV
210 220 230 240 250
FLEHQLPLNS DYSLLLTFIY GGRVVGKTQV HSLDCRLVAE RSDSESSMEQ
260 270 280 290 300
VEFPKPDPLE PTQHLLNQLD RGVLVASNSR GLFVQRLCPI PISWNAPEAP
310 320 330 340 350
PGPGPHLLPS NKCVELFKTT YFCRDLAQYF QGQGPPPKFQ ATLHFWEESP
360 370 380 390
GSSHSQENLI TVQMEQAFAR HLLEKIPEEE KAALFLLQHT EQSPSALGH
Length:399
Mass (Da):44,610
Last modified:October 11, 2005 - v1
Checksum:i92F9481ACEB669BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK145911 mRNA. Translation: BAE26744.1.
CH466535 Genomic DNA. Translation: EDL36274.1.
RefSeqiNP_032420.1. NM_008394.3.
UniGeneiMm.2032.

Genome annotation databases

GeneIDi16391.
KEGGimmu:16391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK145911 mRNA. Translation: BAE26744.1.
CH466535 Genomic DNA. Translation: EDL36274.1.
RefSeqiNP_032420.1. NM_008394.3.
UniGeneiMm.2032.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000120525.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi16391.
KEGGimmu:16391.

Organism-specific databases

CTDi10379.
MGIiMGI:107587. Irf9.

Phylogenomic databases

eggNOGiENOG410IECM. Eukaryota.
ENOG4111AEC. LUCA.
HOGENOMiHOG000010107.
HOVERGENiHBG003072.
KOiK04693.

Miscellaneous databases

ChiTaRSiIrf9. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000002325.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.200.10. 1 hit.
InterProiView protein in InterPro
IPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR019471. Interferon_reg_factor-3.
IPR017855. SMAD_dom-like.
IPR008984. SMAD_FHA_domain.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11949. PTHR11949. 1 hit.
PfamiView protein in Pfam
PF00605. IRF. 1 hit.
PF10401. IRF-3. 1 hit.
PRINTSiPR00267. INTFRNREGFCT.
SMARTiView protein in SMART
SM00348. IRF. 1 hit.
SM01243. IRF-3. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF49879. SSF49879. 1 hit.
PROSITEiView protein in PROSITE
PS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UKQ7_MOUSE
AccessioniPrimary (citable) accession number: Q3UKQ7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: March 15, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.