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Protein
Submitted name:

NAD-dependent protein deacetylase sirtuin-6

Gene

Sirt6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
NAD-dependent protein deacetylase sirtuin-6Imported
Gene namesi
Name:Sirt6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1354161. Sirt6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000034748.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 234Deacetylase sirtuin-typeInterPro annotationAdd BLAST234

Phylogenomic databases

eggNOGiKOG1905. Eukaryota.
COG0846. LUCA.
GeneTreeiENSGT00530000063706.
HOGENOMiHOG000231240.
HOVERGENiHBG060028.

Family and domain databases

Gene3Di3.40.50.1220. 1 hit.
InterProiView protein in InterPro
IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
PfamiView protein in Pfam
PF02146. SIR2. 2 hits.
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiView protein in PROSITE
PS50305. SIRTUIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UKP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFENAR
60 70 80 90 100
PSKTHMALVQ LERMGFLSFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE
110 120 130 140 150
CPKCKTQYVR DTVVGTMGLK ATGRLCTVAK TRGLRACRGE LRDTILDWED
160 170 180 190 200
SLPDRDLMLA DEASRTADLS VTLGTSLQIR PSGNLPLATK RRGGRLVIVN
210 220 230 240 250
LQPTKHDRQA DLRIHGYVDE VMCRLMKHLG LEIPAWDGPC VLDKALPPLP
260 270 280 290
RPVALKAEPP VHLNGAVHVS YKSKPNSPIL HRPPKRVKTE AAPS
Length:294
Mass (Da):32,443
Last modified:October 11, 2005 - v1
Checksum:i3541FDBBFF16A7FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153919 Genomic DNA. No translation available.
AK145929 mRNA. Translation: BAE26760.1.
RefSeqiNP_001156902.1. NM_001163430.1.
UniGeneiMm.131825.
Mm.25643.

Genome annotation databases

EnsembliENSMUST00000119324; ENSMUSP00000113953; ENSMUSG00000034748.
GeneIDi50721.

Similar proteinsi

Entry informationi

Entry nameiQ3UKP1_MOUSE
AccessioniPrimary (citable) accession number: Q3UKP1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported