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Protein
Submitted name:

Putative uncharacterized protein

Gene

Nae1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. NEDD8 activating enzyme activity Source: GO_Central
  2. protein heterodimerization activity Source: MGI
  3. ubiquitin protein ligase binding Source: MGI

GO - Biological processi

  1. mitotic DNA replication checkpoint Source: MGI
  2. neuron apoptotic process Source: MGI
  3. protein neddylation Source: MGI
  4. regulation of apoptotic process Source: MGI
  5. regulation of neuron apoptotic process Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Nae1Imported
Synonyms:Appbp1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2384561. Nae1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: GO_Central
  2. nucleus Source: GO_Central
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3UK27.

Expressioni

Gene expression databases

BgeeiQ3UK27.
ExpressionAtlasiQ3UK27. baseline and differential.
GenevestigatoriQ3UK27.

Structurei

3D structure databases

ProteinModelPortaliQ3UK27.
SMRiQ3UK27. Positions 9-534.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG079761.
KOiK04532.
OMAiKSYKEKE.
PhylomeDBiQ3UK27.

Family and domain databases

Gene3Di3.40.50.720. 3 hits.
InterProiIPR030667. APP-BP1.
IPR009036. Molybdenum_cofac_synth_MoeB.
IPR016040. NAD(P)-bd_dom.
IPR000594. ThiF_NAD_FAD-bd.
[Graphical view]
PfamiPF00899. ThiF. 1 hit.
[Graphical view]
PIRSFiPIRSF039099. APP-BP1. 1 hit.
SUPFAMiSSF69572. SSF69572. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UK27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQPGKILKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV
60 70 80 90 100
LPGIGSFTII DGNLVSGEDA GNNFFLQKSS IGKNRAQAAM EFLQELNSDV
110 120 130 140 150
SGSFVEESPE NLLDNDPSFF CRFTIVVATQ LLESTLLRLA DVLWNSQIPL
160 170 180 190 200
LICRTYGLVG YMRIIIKEHP VIESHPDNAL EDLRLDKPFP ELREHLQSYD
210 220 230 240 250
LDHMEKKDHS HTPWIVIIAK YLAQWYNETN GRIPKSYKEK EDFRDLIRQG
260 270 280 290 300
ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ
310 320 330 340 350
TPTFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSNKYI KLQNVYREKA
360 370 380 390 400
KKDAAAVGNH VAKLLQSVGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE
410 420 430 440 450
EYGLDTVNKD EIISSMDNPD NEIVLYLMLR AVDRFHKQHG RYPGVSNYQV
460 470 480 490 500
EEDIGKLKSC LTGFLQEYGL SVMVKDDYVH EFCRYGAAEP HTIAAFLGGA
510 520 530
AAQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL
Length:534
Mass (Da):60,274
Last modified:October 11, 2005 - v1
Checksum:i5CFCABFE5FA7AC62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146202 mRNA. Translation: BAE26975.1.
RefSeqiNP_659180.1. NM_144931.3.
UniGeneiMm.237670.

Genome annotation databases

GeneIDi234664.
KEGGimmu:234664.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146202 mRNA. Translation: BAE26975.1.
RefSeqiNP_659180.1. NM_144931.3.
UniGeneiMm.237670.

3D structure databases

ProteinModelPortaliQ3UK27.
SMRiQ3UK27. Positions 9-534.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ3UK27.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi234664.
KEGGimmu:234664.

Organism-specific databases

CTDi8883.
MGIiMGI:2384561. Nae1.

Phylogenomic databases

HOVERGENiHBG079761.
KOiK04532.
OMAiKSYKEKE.
PhylomeDBiQ3UK27.

Miscellaneous databases

NextBioi382253.
SOURCEiSearch...

Gene expression databases

BgeeiQ3UK27.
ExpressionAtlasiQ3UK27. baseline and differential.
GenevestigatoriQ3UK27.

Family and domain databases

Gene3Di3.40.50.720. 3 hits.
InterProiIPR030667. APP-BP1.
IPR009036. Molybdenum_cofac_synth_MoeB.
IPR016040. NAD(P)-bd_dom.
IPR000594. ThiF_NAD_FAD-bd.
[Graphical view]
PfamiPF00899. ThiF. 1 hit.
[Graphical view]
PIRSFiPIRSF039099. APP-BP1. 1 hit.
SUPFAMiSSF69572. SSF69572. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2000)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2004)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2Imported.

Entry informationi

Entry nameiQ3UK27_MOUSE
AccessioniPrimary (citable) accession number: Q3UK27
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 1, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.