Q3UHU8 (Q3UHU8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
General transcription factor II-I Ensembl ENSMUSP00000133444

Gene names

Name:

Gtf2i MGI 1202722 Ensembl ENSMUSP00000133444

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	962 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	embryo development Inferred from mutant phenotype PubMed 19109438. Source: MGI
Cellular_component	cell projection Inferred from direct assay PubMed 14751286. Source: MGI neuronal cell body Inferred from direct assay PubMed 14751286. Source: MGI nucleus Inferred from direct assay PubMed 14751286PubMed 17052463. Source: MGI
Molecular_function	mitogen-activated protein kinase binding Inferred from direct assay PubMed 17052463. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3UHU8 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 942BB9ACF1F54A9F	FASTA	962	108,350
	10 20 30 40 50 60 MAQVVMSALP AEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 70 80 90 100 110 120 RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 130 140 150 160 170 180 CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPEHYDLATL KWILENKAGI 190 200 210 220 230 240 SFIIKRPFLE PKKHLGGRVL AAEAERSMLS PSGSCGPIKV KTEPTEDSGI SLEMAAVTVK 250 260 270 280 290 300 EESEDPDYYQ YNIQGSHHSS EGNEGTEVEV PAEDDDYSPP TKRLKSTEPP PPPPVPEPAN 310 320 330 340 350 360 AGKRKVREFN FEKWNARITD LRKQVEELFE RKYAQAIKAK GPVTIPYPLF QSHVEDLYVE 370 380 390 400 410 420 GLPEGIPFRR PSTYGIPRLE RILLAKERIR FVIKKHELLN STREDLQLDK PASGVKEEWY 430 440 450 460 470 480 ARITKLRKMV DQLFCKKFAE ALGSTEAKAV PYQKFEAHPN DLYVEGLPEN IPFRSPSWYG 490 500 510 520 530 540 IPRLEKIIQV GNRIKFVIKR PELLTHSTTE VTQPRTNTPV KEDWNVRITK LRKQVEEIFN 550 560 570 580 590 600 LKFAQALGLT EAVKVPYPVF ESNPEFLYVE GLPEGIPFRS PTWFGIPRLE RIVRGSNKIK 610 620 630 640 650 660 FVVKKPELVV SYLPPGMASK INTKALQSPK RPRSPGSNSK VPEIEVTVEG PNNSSPQTSA 670 680 690 700 710 720 VRTPTQTNGS NVPFKPRGRE FSFEAWNAKI TDLKQKVENL FNEKCGEALG LKQAVKVPFA 730 740 750 760 770 780 LFESFPEDFY VEGLPEGVPF RRPSTFGIPR LEKILRNKAK IKFIIKKPEM FETAIKESTS 790 800 810 820 830 840 SKSPPIFLSG KINSSPNVNT TASGVEDLNI IQVTIPDDDN ERLSKVEKAR QLREQVNDLF 850 860 870 880 890 900 SRKFGEAIGM GFPVKVPYRK ITINPGCVVV DGMPPGVSFK APSYLEISSM RRILDSAEFI 910 920 930 940 950 960 KFTVIRPFPG LVINNQLVDQ NESEGPVIQE SAEASQLEVP VTEEIKETDG SSQIKQEPDP TW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[5]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[6]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27759.1. Tissue: Whole body EMBL BAE27759.1.
[9]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000133444.
[10]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000133444.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC093346 Genomic DNA. No translation available. AK147201 mRNA. Translation: BAE27759.1.
IPI	IPI00229538.
RefSeq	NP_001074218.1. NM_001080749.1.
UniGene	Mm.261570. Mm.412191.
3D structure databases
SMR	Q3UHU8. Positions 104-197, 319-414, 426-516, 531-609, 691-783, 818-918.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000173341; ENSMUSP00000133444; ENSMUSG00000060261.
GeneID	14886.
KEGG	mmu:14886.
UCSC	uc008zvq.1. mouse.
Organism-specific databases
CTD	2969.
MGI	MGI:1202722. Gtf2i.
Phylogenomic databases
GeneTree	ENSGT00530000063863.
HOVERGEN	HBG051856.
KO	K03121.
Gene expression databases
Genevestigator	Q3UHU8.
Family and domain databases
Gene3D	3.90.1460.10. 6 hits.
InterPro	IPR004212. GTF2I. IPR016659. TF_II-I. [Graphical view]
Pfam	PF02946. GTF2I. 6 hits. [Graphical view]
PIRSF	PIRSF016441. TF_II-I. 1 hit.
SUPFAM	SSF117773. SSF117773. 6 hits.
PROSITE	PS51139. GTF2I. 6 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	GTF2I. mouse.
NextBio	287171.
SOURCE	Search...

Entry information

Entry name

Q3UHU8_MOUSE

Accession

Primary (citable) accession number: Q3UHU8

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)