Q3UHJ1 (Q3UHJ1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000058361 Ensembl ENSMUSP00000112517

Gene names

Name:

Traf3 Ensembl ENSMUSP00000058361 MGI 108041 Ensembl ENSMUSP00000112517

Organism

Mus musculus (Mouse) EMBL BAE27866.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	542 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 MATH domain. RuleBase RU004402 Contains 1 RING-type zinc finger. SAAS SAAS013323

Ontologies

Keywords
Domain	Zinc-finger SAAS SAAS013323 RuleBase RU000353
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of apoptotic process Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Molecular function	ubiquitin-protein ligase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3UHJ1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 63DF0A68EF3422A8	FASTA	542	61,564
	10 20 30 40 50 60 MESSKKMDAA GTLQPNPPLK LQPDRGAGSV LVPEQGGYKE KFVKTVEDKY KCEKCRLVLC 70 80 90 100 110 120 NPKQTECGHR FCESCMAALL SSSSPKCTAC QESIIKDKVF KDNCCKREIL ALQVYCRNEG 130 140 150 160 170 180 RGCAEQLTLG HLLVHLKNEC QFEELPCLRA DCKEKVLRKD LRDHVEKACK YREATCSHCK 190 200 210 220 230 240 SQVPMIKLQK HEDTDCPCVV VSCPHKCSVQ TLLRSEGTNQ QIKAHEASSA VQHVNLLKEW 250 260 270 280 290 300 SNSLEKKVSL LQNESVEKNK SIQSLHNQIC SFEIEIERQK EMLRNNESKI LHLQRVIDSQ 310 320 330 340 350 360 AEKLKELDKE IRPFRQNWEE ADSMKSSVES LQNRVTELES VDKSAGQAAR NTGLLESQLS 370 380 390 400 410 420 RHDQMLSVHD IRLADMDLRF QVLETASYNG VLIWKIRDYK RRKQEAVMGK TLSLYSQPFY 430 440 450 460 470 480 TGYFGYKMCA RVYLNGDGMG KGTHLSLFFV IMRGEYDALL PWPFKQKVTL MLMDQGSSRR 490 500 510 520 530 540 HLGDAFKPDP NSSSFKKPTG EMNIASGCPV FVAQTVLENG TYIKDDTIFI KVIVDTSDLP DP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed: 16141073] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[2]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed: 11076861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000058361 Ensembl ENSMUSP00000112517.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[5]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed: 10349636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[6]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed: 11042159] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[7]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[8]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[9]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAE27866.1. Tissue: Brain EMBL BAE27866.1.
[10]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000058361 Ensembl ENSMUSP00000112517.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC122023 Genomic DNA. No translation available. AC127580 Genomic DNA. No translation available. AK147362 mRNA. Translation: BAE27866.1.
IPI	IPI00788392.
RefSeq	NP_001041671.1. NM_001048206.1. NP_035762.2. NM_011632.2.
UniGene	Mm.27431.
3D structure databases
ProteinModelPortal	Q3UHJ1.
SMR	Q3UHJ1. Positions 36-225, 351-542.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q3UHJ1. 1 interaction.
STRING	Q3UHJ1.
Proteomic databases
PRIDE	Q3UHJ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000060274; ENSMUSP00000058361; ENSMUSG00000021277. ENSMUST00000117269; ENSMUSP00000112517; ENSMUSG00000021277.
GeneID	22031.
KEGG	mmu:22031.
UCSC	uc007pcm.1. mouse.
Organism-specific databases
CTD	7187.
MGI	MGI:108041. Traf3.
Phylogenomic databases
HOVERGEN	HBG058222.
Gene expression databases
ArrayExpress	Q3UHJ1.
Bgee	Q3UHJ1.
Genevestigator	Q3UHJ1.
Family and domain databases
InterPro	IPR002083. MATH. IPR013323. SIAH-type. IPR012227. TNF_rcpt--assoc_TRAF. IPR008974. TRAF-like. IPR013322. TRAF-type. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. IPR001293. Znf_TRAF. [Graphical view]
Gene3D	G3DSA:3.90.890.10. SIAH-type. 1 hit. G3DSA:2.60.210.10. TRAF-type. 1 hit. G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit.
KO	K03174.
Pfam	PF00917. MATH. 1 hit. [Graphical view]
PIRSF	PIRSF015614. TRAF. 1 hit.
SMART	SM00061. MATH. 1 hit. SM00184. RING. 1 hit. [Graphical view]
SUPFAM	SSF49599. Traf_like. 2 hits.
PROSITE	PS50144. MATH. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. PS50145. ZF_TRAF. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	301784.
SOURCE	Search...

Entry information

Entry name

Q3UHJ1_MOUSE

Accession

Primary (citable) accession number: Q3UHJ1

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	November 16, 2011
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)