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Protein
Submitted name:

Putative uncharacterized protein

Gene

Hspg2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Hspg2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96257. Hspg2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 26722647Sequence analysisPRO_5007702562Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiQ3UHH3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000131316.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini80 – 191112SEAInterPro annotationAdd
BLAST
Domaini406 – 48479Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini545 – 730186Laminin IV type AInterPro annotationAdd
BLAST
Domaini764 – 81350Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini814 – 87158Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini878 – 92346Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini948 – 1125178Laminin IV type AInterPro annotationAdd
BLAST
Domaini1159 – 120850Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini1209 – 126557Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini1275 – 132450Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini1351 – 1529179Laminin IV type AInterPro annotationAdd
BLAST
Domaini1563 – 161250Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini1613 – 167058Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini1670 – 176394Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini1769 – 185991Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini1865 – 194884Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini1955 – 203884Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini2051 – 213282Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini2145 – 223187Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini2245 – 232278Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini2342 – 2582241LAM_G_DOMAINInterPro annotationAdd
BLAST

Keywords - Domaini

Laminin EGF-like domainSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3509. Eukaryota.
ENOG410XTD2. LUCA.
HOVERGENiHBG008174.
KOiK06255.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
2.60.40.10. 8 hits.
4.10.400.10. 4 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EGF-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013106. Ig_V-set.
IPR002049. Laminin_EGF.
IPR001791. Laminin_G.
IPR000034. Laminin_IV.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR000082. SEA_dom.
[Graphical view]
PfamiPF07679. I-set. 4 hits.
PF00052. Laminin_B. 3 hits.
PF00053. Laminin_EGF. 9 hits.
PF00054. Laminin_G_1. 1 hit.
PF00057. Ldl_recept_a. 4 hits.
[Graphical view]
PRINTSiPR00261. LDLRECEPTOR.
SMARTiSM00181. EGF. 6 hits.
SM00180. EGF_Lam. 9 hits.
SM00409. IG. 9 hits.
SM00408. IGc2. 8 hits.
SM00406. IGv. 4 hits.
SM00281. LamB. 3 hits.
SM00282. LamG. 1 hit.
SM00192. LDLa. 4 hits.
SM00200. SEA. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 8 hits.
SSF49899. SSF49899. 2 hits.
SSF57424. SSF57424. 4 hits.
PROSITEiPS01248. EGF_LAM_1. 11 hits.
PS50027. EGF_LAM_2. 8 hits.
PS50835. IG_LIKE. 8 hits.
PS50025. LAM_G_DOMAIN. 1 hit.
PS51115. LAMININ_IVA. 3 hits.
PS01209. LDLRA_1. 4 hits.
PS50068. LDLRA_2. 4 hits.
PS50024. SEA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UHH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQRAVGSLL LGLLLHARLL AVTHGLRAYD GLSLPEDTET VTASRYGWTY
60 70 80 90 100
SYLSDDEDLL ADDASGDGLG SGDVGSGDFQ MVYFRALVNF TRSIEYSPQL
110 120 130 140 150
EDASAKEFRE VSEAVVEKLE PEYRKIPGDQ IVSVVFIKEL DGWVFVELDV
160 170 180 190 200
GSEGNADGSQ IQEVLHTVVS SGSIGPYVTS PWGFKFRRLG TVPQFPRVCT
210 220 230 240 250
ETEFACHSYN ECVALEYRCD RRPDCRDMSD ELNCEEPVPE LSSSTPAVGK
260 270 280 290 300
VSPLPLWPEA ATTPPPPVTH GPQFLLPSVP GPSACGPQEA SCHSGHCIPR
310 320 330 340 350
DYLCDGQEDC RDGSDELGCA SPPPCEPNEF ACENGHCALK LWRCDGDFDC
360 370 380 390 400
EDRTDEANCS VKQPGEVCGP THFQCVSTNR CIPASFHCDE ESDCPDRSDE
410 420 430 440 450
FGCMPPQVVT PPQQSIQASR GQTVTFTCVA TGVPTPIINW RLNWGHIPAH
460 470 480 490 500
PRVTMTSEGG RGTLIIRDVK EADQGAYTCE AMNSRGMVFG IPDGVLELVP
510 520 530 540 550
QRGPCPDGHF YLEDSASCLP CFCFGVTNVC QSSLRFRDQI RLSFDQPNDF
560 570 580 590 600
KGVNVTMPSQ PGVPPLSSTQ LQIDPALQEF QLVDLSRRFL VHDAFWALPK
610 620 630 640 650
QFLGNKVDSY GGFLRYKVRY ELARGMLEPV QKPDVILVGA GYRLHSRGHT
660 670 680 690 700
PTHPGTLNQR QVQLSEEHWV HESGRPVQRA EMLQALASLE AVLLQTVYNT
710 720 730 740 750
KMASVGLSDI VMDTTVTHTT IHGRAHSVEE CRCPIGYSGL SCESCDAHFT
760 770 780 790 800
RVPGGPYLGT CSGCNCNGHA SSCDPVYGHC LNCQHNTEGP QCDKCKPGFF
810 820 830 840 850
GDATKATATA CRPCPCPYID ASRRFSDTCF LDTDGQATCD ACAPGYTGRR
860 870 880 890 900
CESCAPGYEG NPIQPGGKCR PTTQEIVRCD ERGSLGTSGE TCRCKNNVVG
910 920 930 940 950
RLCNECSDGS FHLSKQNPDG CLKCFCMGVS RQCSSSSWSR AQVLGASEQP
960 970 980 990 1000
SQFSLSNAAG THTTSEGVSS PAPGELSFSS FHNLLSEPYF WSLPASFRGD
1010 1020 1030 1040 1050
KVTSYGGELR FTVTQRPRPS SAPLHRQPLV VLQGNNIVLE HHASRDPSPG
1060 1070 1080 1090 1100
QPSNFIVPFQ EQAWQRPDGQ PATREHLLMA LAGIDALLIQ ASYTQQPAES
1110 1120 1130 1140 1150
RVSGISMDVA VPENTGQDSA REVEQCTCPP GYRGPSCQDC DTGYTRVPSG
1160 1170 1180 1190 1200
LYLGTCERCN CHGHSETCEP ETGACQSCQH HTEGASCEQC QPGYYGDAQR
1210 1220 1230 1240 1250
GTPQDCQPCP CYGAPAAGQA AHTCFLDTDG HPTCDSCSPG HSGRHCERCA
1260 1270 1280 1290 1300
PGYYGNPSQG QPCHRDGQVP EVLGCGCDPH GSISSQCDAA GQCQCKAQVE
1310 1320 1330 1340 1350
GRTCSHCRPH HFHLSASNPE GCLPCFCMGV TQQCASSSYS RQLISTHFAP
1360 1370 1380 1390 1400
GDFQGFALVN PQRNSQLTGG FTVEPVHDGA RLSFSNFAHL GQESFYWQLP
1410 1420 1430 1440 1450
EIYQGDKVAA YGGKLRYTLS YTAGPQGSPL LDPDIQITGN NIMLVASQPA
1460 1470 1480 1490 1500
LQGPERRSYE IIFREEFWRR PDGQPATREH LLMALADLDE LLVRATFSSV
1510 1520 1530 1540 1550
PRAASISAVS LEVAQPGPSS GPRALEVEEC RCPPGYVGLS CQDCAPGYTR
1560 1570 1580 1590 1600
TGSGLYLGQC ELCECNGHSD LCHPETGACS RCQHNTAGEF CELCATGYYG
1610 1620 1630 1640 1650
DATAGTPEDC QPCACPLTNP ENMFSRTCES LGAGGYRCTA CEPGYTGQYC
1660 1670 1680 1690 1700
EQCAPGYEGD PNVQGGRCQP LTKESLEVQI HPSRSVVPQG GPHSLRCQVS
1710 1720 1730 1740 1750
GSPPHYFYWS REDGRPLPSS AQQRHQGSEL HFPSVQPSDA GVYICTCRNL
1760 1770 1780 1790 1800
IHTSNSRAEL LVAEAPSKPI TVTVEEQRSQ SVRPGADVTF ICTAKSKSPA
1810 1820 1830 1840 1850
YTLVWTRLHN GKLPSRAMDF NGILTIRNVQ PSDAGTYVCT GSNMFAMDQG
1860 1870 1880 1890 1900
TATLHVQVSG TSTAPVASIH PPQLTVQPGQ QAEFRCSATG NPTPMLEWIG
1910 1920 1930 1940 1950
GPSGQLPAKA QIHNGILRLP AIEPSDQGQY LCRALSSAGQ HVARAMLQVH
1960 1970 1980 1990 2000
GGSGPRVQVS PERTQVHEGR TVRLYCRAAG VPSASITWRK EGGSLPPQAR
2010 2020 2030 2040 2050
SENTDIPTLL IPAITAADAG FYLCVATSPT GTAQARIQVV VLSASGANSV
2060 2070 2080 2090 2100
PVRIESSSPS VTEGQTLDLN CAVMGLTYTQ VTWYKRGGSL PPHAQVHGSR
2110 2120 2130 2140 2150
LRLPQVSPAD SGDYVCRVES DVGPKEASIV VSVLHSPHSG PSYTPATSIT
2160 2170 2180 2190 2200
PPIRIESSSS HVAEGQTLDL NCVVPGQAQV TWRKRGGSLP ARHQTHGSLL
2210 2220 2230 2240 2250
RLHQVSPADS GEYVCHVVLG SEHTETSVLV TIEPAESIPA PGPAPPVRIE
2260 2270 2280 2290 2300
ASSSTVTEGH MLDLNCVVAG QAHAQVTWYK RGGSLPARHQ VRGSRLYILQ
2310 2320 2330 2340 2350
ASPADAGEYV CRAGNGQEAT ITVTVTRNHG ANLAYPPGST SPIRIESSSS
2360 2370 2380 2390 2400
HVAEGQTLDL NCVVPEVPET IEFEVRTSTA DGLLLWQGVV REASRSKDFI
2410 2420 2430 2440 2450
SLGLQDGHLV FSYQLGSGEA RLVSEDPIND GEWHRITALR EGQRGSIQVD
2460 2470 2480 2490 2500
GEDLVTGRSP GPNVAVNTKD IIYIGGAPDV ATLTRGKFSS GSQAVSRIWC
2510 2520 2530 2540 2550
CTRPGLEPHL HSPWTCSIAP RQGPTHGPAP HRHPPASHGL LGSTQPDSVE
2560 2570 2580 2590 2600
YIIINIIMTF CKRLRQGHAS LLPPWAGLEG GCANSHAFVG RAPRLVGRTR
2610 2620 2630 2640 2650
GLEEVSSEGS RNLESGIVTG RAQNCSHPFP CFSVRLGHPL QQAVRADSPH
2660 2670
CCERSYHLVP HCQTERGGVA MA
Length:2,672
Mass (Da):287,511
Last modified:October 11, 2005 - v1
Checksum:iDA405D88031E1EDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147294 mRNA. Translation: BAE27828.1.
AK147396 mRNA. Translation: BAE27884.1.
RefSeqiNP_032331.2. NM_008305.3.
UniGeneiMm.273662.

Genome annotation databases

GeneIDi15530.
KEGGimmu:15530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147294 mRNA. Translation: BAE27828.1.
AK147396 mRNA. Translation: BAE27884.1.
RefSeqiNP_032331.2. NM_008305.3.
UniGeneiMm.273662.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000131316.

Proteomic databases

PeptideAtlasiQ3UHH3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15530.
KEGGimmu:15530.

Organism-specific databases

CTDi3339.
MGIiMGI:96257. Hspg2.

Phylogenomic databases

eggNOGiKOG3509. Eukaryota.
ENOG410XTD2. LUCA.
HOVERGENiHBG008174.
KOiK06255.

Miscellaneous databases

ChiTaRSiHspg2. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
2.60.40.10. 8 hits.
4.10.400.10. 4 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EGF-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013106. Ig_V-set.
IPR002049. Laminin_EGF.
IPR001791. Laminin_G.
IPR000034. Laminin_IV.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR000082. SEA_dom.
[Graphical view]
PfamiPF07679. I-set. 4 hits.
PF00052. Laminin_B. 3 hits.
PF00053. Laminin_EGF. 9 hits.
PF00054. Laminin_G_1. 1 hit.
PF00057. Ldl_recept_a. 4 hits.
[Graphical view]
PRINTSiPR00261. LDLRECEPTOR.
SMARTiSM00181. EGF. 6 hits.
SM00180. EGF_Lam. 9 hits.
SM00409. IG. 9 hits.
SM00408. IGc2. 8 hits.
SM00406. IGv. 4 hits.
SM00281. LamB. 3 hits.
SM00282. LamG. 1 hit.
SM00192. LDLa. 4 hits.
SM00200. SEA. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 8 hits.
SSF49899. SSF49899. 2 hits.
SSF57424. SSF57424. 4 hits.
PROSITEiPS01248. EGF_LAM_1. 11 hits.
PS50027. EGF_LAM_2. 8 hits.
PS50835. IG_LIKE. 8 hits.
PS50025. LAM_G_DOMAIN. 1 hit.
PS51115. LAMININ_IVA. 3 hits.
PS01209. LDLRA_1. 4 hits.
PS50068. LDLRA_2. 4 hits.
PS50024. SEA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: PlacentaImported.

Entry informationi

Entry nameiQ3UHH3_MOUSE
AccessioniPrimary (citable) accession number: Q3UHH3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 6, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.