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Q3UHB5

- Q3UHB5_MOUSE

UniProt

Q3UHB5 - Q3UHB5_MOUSE

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Protein
Submitted name:

Mitogen-activated protein kinase 8 interacting protein 3, isoform CRA_a

Gene

Mapk8ip3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. activation of JUN kinase activity Source: MGI
  2. axon guidance Source: MGI
  3. forebrain development Source: MGI
  4. in utero embryonic development Source: MGI
  5. JNK cascade Source: MGI
  6. lung alveolus development Source: MGI
  7. lung morphogenesis Source: MGI
  8. positive regulation of neuron differentiation Source: Ensembl
  9. post-embryonic development Source: MGI
  10. protein localization Source: MGI
  11. regulation of gene expression Source: MGI
  12. respiratory gaseous exchange Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase 8 interacting protein 3, isoform CRA_aImported
Gene namesi
Name:Mapk8ip3Imported
ORF Names:mCG_17657Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1353598. Mapk8ip3.

Subcellular locationi

GO - Cellular componenti

  1. axolemma Source: MGI
  2. cytoplasm Source: MGI
  3. dendrite Source: MGI
  4. plasma membrane Source: MGI
  5. smooth endoplasmic reticulum Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ3UHB5.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000290716.
HOVERGENiHBG024110.
KOiK04436.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UHB5-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MMEIQMDEGG GVVVYQDDYC SGSVMSERVS GLAGSIYREF ERLIHCYDEE
60 70 80 90 100
VVKELMPLVV NVLENLDSVL SENQEHEVEL ELLREDNEQL LTQYEREKAL
110 120 130 140 150
RKQAEEKFIE FEDALEQEKK ELQIQVEHYE FQTRQLELKA KNYADQISRL
160 170 180 190 200
EERESEMKKE YNALHQRHTE MIQTYVEHIE RSKMQQVGGS GQTESSLPGR
210 220 230 240 250
SRKERPTSLN VFPLADGMVR AQMGGKLVPA GDHWHLSDLG QLQSSSSYQC
260 270 280 290 300
PNDEMSESGQ SSAAATPSTT GTKSNTPTSS VPSAAVTPLN ESLQPLGDYV
310 320 330 340 350
SVTKNNKQAR EKRNSRNMEV QVTQEMRNVS IGMGSSDEWS DVQDIIDSTP
360 370 380 390 400
ELDVCPETRL ERTGSSPTQG IVNKAFGINT DSLYHELSTA GSEVIGDVDE
410 420 430 440 450
GADLLGEFSV RDDFFGMGKE VGNLLLENSQ LLETKNALNV VKNDLIAKVD
460 470 480 490 500
QLSGEQEVLK GELEAAKQAK VKLENRIKEL EEELKRVKSE AVTARREPRE
510 520 530 540 550
EVEDVSSYLC TELDKIPMAQ RRRFTRVEMA RVLMERNQYK ERLMELQEAV
560 570 580 590 600
RWTEMIRASR EHPSVQEKKK STIWQFFSRL FSSSSSPPPA KRSYPSVNIH
610 620 630 640 650
YKSPTAAGFS QRRSHALCQI SAGSRPLEFF PDDDCTSSAR REQKREQYRQ
660 670 680 690 700
VREHVRNDDG RLQACGWSLP AKYKQLSPNG GQEDTRMKNV PVPVYCRPLV
710 720 730 740 750
EKDPSTKLWC AAGVNLSGWK PHEEDSSNGP KPVPGRDPLT CDREGEGEPK
760 770 780 790 800
STHPSPEKKK AKETPEADAT SSRVWILTST LTTSKVVIID ANQPGTIVDQ
810 820 830 840 850
FTVCNAHVLC ISSIPAASDS DYPPGEMFLD SDVNPEDSGA DGVLAGITLV
860 870 880 890 900
GCATRCNVPR SNCSSRGDTP VLDKGQGDVA TTANGKVNPS QSTEEATEAT
910 920 930 940 950
EVPDPGPSES EATTVRPGPL TEHVFTDPAP TPSSSTQPAS ENGSESNGTI
960 970 980 990 1000
VQPQVEPSGE LSTTTSSAAP TMWLGAQNGW LYVHSAVANW KKCLHSIKLK
1010 1020 1030 1040 1050
DSVLSLVHVK GRVLVALADG TLAIFHRGED GQWDLSNYHL MDLGHPHHSI
1060 1070 1080 1090 1100
RCMAVVNDRV WCGYKNKVHV IQPKTMQIEK SFDAHPRRES QVRQLAWIGD
1110 1120 1130 1140 1150
GVWVSIRLDS TLRLYHAHTH QHLQDVDIEP YVSKMLGTGK LGFSFVRITA
1160 1170 1180 1190 1200
LLIAGNRLWV GTGNGVVISI PLTETVVLHR GQLLGLRANK TSPTSGEGTR
1210 1220 1230 1240 1250
PGGIIHVYGD DSSDKAASSF IPYCSMAQAQ LCFHGHRDAV KFFVSVPGNV
1260 1270 1280 1290 1300
LATLNGSVLD SPSEGPGPAA PAADAEGQKL KNALVLSGGE GYIDFRIGDG
1310 1320 1330
EDDETEECAG DVNQTKPSLS KAERSHIIVW QVSYTPE
Length:1,337
Mass (Da):147,561
Last modified:October 11, 2005 - v1
Checksum:iD7DEE54C17B74106
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK147477 mRNA. Translation: BAE27942.1.
CH466606 Genomic DNA. Translation: EDL22384.1.
RefSeqiNP_038959.2. NM_013931.4.
UniGeneiMm.43081.

Genome annotation databases

GeneIDi30957.
KEGGimmu:30957.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK147477 mRNA. Translation: BAE27942.1 .
CH466606 Genomic DNA. Translation: EDL22384.1 .
RefSeqi NP_038959.2. NM_013931.4.
UniGenei Mm.43081.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 30957.
KEGGi mmu:30957.

Organism-specific databases

CTDi 23162.
MGIi MGI:1353598. Mapk8ip3.

Phylogenomic databases

HOGENOMi HOG000290716.
HOVERGENi HBG024110.
KOi K04436.

Miscellaneous databases

NextBioi 307444.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3UHB5.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ3UHB5_MOUSE
AccessioniPrimary (citable) accession number: Q3UHB5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)