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Q3UHB5

- Q3UHB5_MOUSE

UniProt

Q3UHB5 - Q3UHB5_MOUSE

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Protein
Submitted name:

Mitogen-activated protein kinase 8 interacting protein 3, isoform CRA_a

Gene
Mapk8ip3, mCG_17657
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. protein binding Source: MGI

GO - Biological processi

  1. activation of JUN kinase activity Source: MGI
  2. axon guidance Source: MGI
  3. forebrain development Source: MGI
  4. in utero embryonic development Source: MGI
  5. JNK cascade Source: MGI
  6. lung alveolus development Source: MGI
  7. lung morphogenesis Source: MGI
  8. positive regulation of neuron differentiation Source: Ensembl
  9. post-embryonic development Source: MGI
  10. protein localization Source: MGI
  11. regulation of gene expression Source: MGI
  12. respiratory gaseous exchange Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase 8 interacting protein 3, isoform CRA_aImported
Gene namesi
Name:Mapk8ip3Imported
ORF Names:mCG_17657Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1353598. Mapk8ip3.

Subcellular locationi

GO - Cellular componenti

  1. axolemma Source: MGI
  2. cytoplasm Source: MGI
  3. dendrite Source: MGI
  4. plasma membrane Source: MGI
  5. smooth endoplasmic reticulum Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ3UHB5.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000290716.
HOVERGENiHBG024110.
KOiK04436.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3UHB5-1 [UniParc]FASTAAdd to Basket

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MMEIQMDEGG GVVVYQDDYC SGSVMSERVS GLAGSIYREF ERLIHCYDEE     50
VVKELMPLVV NVLENLDSVL SENQEHEVEL ELLREDNEQL LTQYEREKAL 100
RKQAEEKFIE FEDALEQEKK ELQIQVEHYE FQTRQLELKA KNYADQISRL 150
EERESEMKKE YNALHQRHTE MIQTYVEHIE RSKMQQVGGS GQTESSLPGR 200
SRKERPTSLN VFPLADGMVR AQMGGKLVPA GDHWHLSDLG QLQSSSSYQC 250
PNDEMSESGQ SSAAATPSTT GTKSNTPTSS VPSAAVTPLN ESLQPLGDYV 300
SVTKNNKQAR EKRNSRNMEV QVTQEMRNVS IGMGSSDEWS DVQDIIDSTP 350
ELDVCPETRL ERTGSSPTQG IVNKAFGINT DSLYHELSTA GSEVIGDVDE 400
GADLLGEFSV RDDFFGMGKE VGNLLLENSQ LLETKNALNV VKNDLIAKVD 450
QLSGEQEVLK GELEAAKQAK VKLENRIKEL EEELKRVKSE AVTARREPRE 500
EVEDVSSYLC TELDKIPMAQ RRRFTRVEMA RVLMERNQYK ERLMELQEAV 550
RWTEMIRASR EHPSVQEKKK STIWQFFSRL FSSSSSPPPA KRSYPSVNIH 600
YKSPTAAGFS QRRSHALCQI SAGSRPLEFF PDDDCTSSAR REQKREQYRQ 650
VREHVRNDDG RLQACGWSLP AKYKQLSPNG GQEDTRMKNV PVPVYCRPLV 700
EKDPSTKLWC AAGVNLSGWK PHEEDSSNGP KPVPGRDPLT CDREGEGEPK 750
STHPSPEKKK AKETPEADAT SSRVWILTST LTTSKVVIID ANQPGTIVDQ 800
FTVCNAHVLC ISSIPAASDS DYPPGEMFLD SDVNPEDSGA DGVLAGITLV 850
GCATRCNVPR SNCSSRGDTP VLDKGQGDVA TTANGKVNPS QSTEEATEAT 900
EVPDPGPSES EATTVRPGPL TEHVFTDPAP TPSSSTQPAS ENGSESNGTI 950
VQPQVEPSGE LSTTTSSAAP TMWLGAQNGW LYVHSAVANW KKCLHSIKLK 1000
DSVLSLVHVK GRVLVALADG TLAIFHRGED GQWDLSNYHL MDLGHPHHSI 1050
RCMAVVNDRV WCGYKNKVHV IQPKTMQIEK SFDAHPRRES QVRQLAWIGD 1100
GVWVSIRLDS TLRLYHAHTH QHLQDVDIEP YVSKMLGTGK LGFSFVRITA 1150
LLIAGNRLWV GTGNGVVISI PLTETVVLHR GQLLGLRANK TSPTSGEGTR 1200
PGGIIHVYGD DSSDKAASSF IPYCSMAQAQ LCFHGHRDAV KFFVSVPGNV 1250
LATLNGSVLD SPSEGPGPAA PAADAEGQKL KNALVLSGGE GYIDFRIGDG 1300
EDDETEECAG DVNQTKPSLS KAERSHIIVW QVSYTPE 1337
Length:1,337
Mass (Da):147,561
Last modified:October 11, 2005 - v1
Checksum:iD7DEE54C17B74106
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK147477 mRNA. Translation: BAE27942.1.
CH466606 Genomic DNA. Translation: EDL22384.1.
RefSeqiNP_038959.2. NM_013931.4.
UniGeneiMm.43081.

Genome annotation databases

GeneIDi30957.
KEGGimmu:30957.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK147477 mRNA. Translation: BAE27942.1 .
CH466606 Genomic DNA. Translation: EDL22384.1 .
RefSeqi NP_038959.2. NM_013931.4.
UniGenei Mm.43081.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 30957.
KEGGi mmu:30957.

Organism-specific databases

CTDi 23162.
MGIi MGI:1353598. Mapk8ip3.

Phylogenomic databases

HOGENOMi HOG000290716.
HOVERGENi HBG024110.
KOi K04436.

Miscellaneous databases

NextBioi 307444.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3UHB5.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ3UHB5_MOUSE
AccessioniPrimary (citable) accession number: Q3UHB5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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