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Protein
Submitted name:

Putative uncharacterized protein

Gene

Numbl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. adherens junction organization Source: MGI
  2. axonogenesis Source: MGI
  3. cytokine-mediated signaling pathway Source: MGI
  4. forebrain development Source: MGI
  5. nervous system development Source: MGI
  6. neuroblast proliferation Source: MGI
  7. positive regulation of dendrite morphogenesis Source: Ensembl
  8. protein metabolic process Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:NumblImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:894702. Numbl.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3UH86.

Expressioni

Gene expression databases

BgeeiQ3UH86.
ExpressionAtlasiQ3UH86. baseline.
GenevestigatoriQ3UH86.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078245.

Structurei

3D structure databases

ProteinModelPortaliQ3UH86.
SMRiQ3UH86. Positions 21-161.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG006672.
KOiK06057.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR016698. Numb/numb-like.
IPR010449. Numb_domain.
IPR011993. PH_like_dom.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF06311. NumbF. 1 hit.
PF00640. PID. 1 hit.
[Graphical view]
PIRSFiPIRSF017607. Numb/numb-like. 1 hit.
SMARTiSM00462. PTB. 1 hit.
[Graphical view]
PROSITEiPS01179. PID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UH86-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKLRQSLRR RKPAYVPEAS RPHQWQADED AVRKGTCSFP VRYLGHVEVE
60 70 80 90 100
ESRGMHVCED AVKKLKAMGR KSVKSVLWVS ADGLRVVDDK TKDLLVDQTI
110 120 130 140 150
EKVSFCAPDR NLDKAFSYIC RDGTTRRWIC HCFLALKDSG ERLSHAVGCA
160 170 180 190 200
FAACLERKQR REKECGVTAA FDASRTSFAR EGSFRLSGGG RPAEREAGDK
210 220 230 240 250
KKAEAAAAPA VAPGPAQPGH VSPTPATTSP GEKGEAGTPV AAGTTAAAIP
260 270 280 290 300
RRHAPLEQLV RQGSFRGFPA LSQKNSPFKR QLSLRLNELP STLQRRTDFQ
310 320 330 340 350
VKGTVPEMEP PGTGDSDGIN ALCTQISSSF ASAGAPASGP PPATTGTSAW
360 370 380 390 400
GEPSVPAAAA FQPGHKRTPS EAERWLEEVS QVAKAQQQQQ QQQQQQQQQQ
410 420 430 440 450
ATSVPPMPTM APTLQPFSAP VGPFDTAAAQ VAVFLPPTHM QPPFVPAYPG
460 470 480 490 500
LGYPPMPRVP VVGITPSQMV ANAFCSAAQL QPQPATLLGK AGAFPPPAAP
510 520 530 540 550
SAPGGQARPR PNGAPWPPEP APAPAPELDP FEAQWAALEG KPAVEKPSNP
560
FSGDLQKTFE IEL
Length:563
Mass (Da):60,080
Last modified:October 11, 2005 - v1
Checksum:i9936788A9145A5CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147523 mRNA. Translation: BAE27971.1.
RefSeqiNP_035080.2. NM_010950.2.
XP_006539680.1. XM_006539617.1.
UniGeneiMm.458153.

Genome annotation databases

GeneIDi18223.
KEGGimmu:18223.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147523 mRNA. Translation: BAE27971.1.
RefSeqiNP_035080.2. NM_010950.2.
XP_006539680.1. XM_006539617.1.
UniGeneiMm.458153.

3D structure databases

ProteinModelPortaliQ3UH86.
SMRiQ3UH86. Positions 21-161.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078245.

Proteomic databases

PRIDEiQ3UH86.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi18223.
KEGGimmu:18223.

Organism-specific databases

CTDi9253.
MGIiMGI:894702. Numbl.

Phylogenomic databases

HOVERGENiHBG006672.
KOiK06057.

Miscellaneous databases

ChiTaRSiNumbl. mouse.
NextBioi293648.
SOURCEiSearch...

Gene expression databases

BgeeiQ3UH86.
ExpressionAtlasiQ3UH86. baseline.
GenevestigatoriQ3UH86.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR016698. Numb/numb-like.
IPR010449. Numb_domain.
IPR011993. PH_like_dom.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF06311. NumbF. 1 hit.
PF00640. PID. 1 hit.
[Graphical view]
PIRSFiPIRSF017607. Numb/numb-like. 1 hit.
SMARTiSM00462. PTB. 1 hit.
[Graphical view]
PROSITEiPS01179. PID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ3UH86_MOUSE
AccessioniPrimary (citable) accession number: Q3UH86
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 4, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.