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Q3UGN1

- Q3UGN1_MOUSE

UniProt

Q3UGN1 - Q3UGN1_MOUSE

Protein

Guanine nucleotide-binding protein subunit gamma

Gene

Gng7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

    GO - Molecular functioni

    1. signal transducer activity Source: MGI

    GO - Biological processi

    1. behavioral fear response Source: MGI
    2. G-protein coupled receptor signaling pathway Source: InterPro
    3. locomotory behavior Source: MGI
    4. receptor guanylyl cyclase signaling pathway Source: MGI

    Keywords - Molecular functioni

    TransducerUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanine nucleotide-binding protein subunit gammaUniRule annotation
    Gene namesi
    Name:Gng7Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:95787. Gng7.

    Subcellular locationi

    Cell membrane UniRule annotation; Lipid-anchor UniRule annotation; Cytoplasmic side UniRule annotation

    GO - Cellular componenti

    1. heterotrimeric G-protein complex Source: InterPro

    Keywords - Cellular componenti

    Cell membraneUniRule annotation, Membrane

    PTM / Processingi

    Keywords - PTMi

    LipoproteinUniRule annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ3UGN1.

    Interactioni

    Subunit structurei

    G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000097061.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G protein gamma family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG014983.
    InParanoidiQ3UGN1.
    KOiK04543.
    OMAiPECHEGV.

    Family and domain databases

    Gene3Di4.10.260.10. 1 hit.
    InterProiIPR015898. G-protein_gamma-like_dom.
    IPR001770. Gprotein-gamma.
    [Graphical view]
    PANTHERiPTHR13809. PTHR13809. 1 hit.
    PfamiPF00631. G-gamma. 1 hit.
    [Graphical view]
    PRINTSiPR00321. GPROTEING.
    SMARTiSM00224. GGL. 1 hit.
    [Graphical view]
    SUPFAMiSSF48670. SSF48670. 1 hit.
    PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3UGN1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSGTNNVAQA RKLVEQLRIE AGIERIKVSK ASSDLMGYCE QHARNDPLLV   50
    GVPASENPFK DKKPCIIL 68
    Length:68
    Mass (Da):7,480
    Last modified:October 11, 2005 - v1
    Checksum:i0F07C667A29ADC07
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK141541 mRNA. Translation: BAE24725.1.
    AK147843 mRNA. Translation: BAE28176.1.
    AK158963 mRNA. Translation: BAE34744.1.
    RefSeqiNP_001033744.1. NM_001038655.1.
    NP_034449.2. NM_010319.3.
    UniGeneiMm.222496.

    Genome annotation databases

    GeneIDi14708.
    KEGGimmu:14708.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK141541 mRNA. Translation: BAE24725.1 .
    AK147843 mRNA. Translation: BAE28176.1 .
    AK158963 mRNA. Translation: BAE34744.1 .
    RefSeqi NP_001033744.1. NM_001038655.1.
    NP_034449.2. NM_010319.3.
    UniGenei Mm.222496.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000097061.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 14708.
    KEGGi mmu:14708.

    Organism-specific databases

    CTDi 2788.
    MGIi MGI:95787. Gng7.

    Phylogenomic databases

    HOVERGENi HBG014983.
    InParanoidi Q3UGN1.
    KOi K04543.
    OMAi PECHEGV.

    Miscellaneous databases

    NextBioi 286695.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3UGN1.

    Family and domain databases

    Gene3Di 4.10.260.10. 1 hit.
    InterProi IPR015898. G-protein_gamma-like_dom.
    IPR001770. Gprotein-gamma.
    [Graphical view ]
    PANTHERi PTHR13809. PTHR13809. 1 hit.
    Pfami PF00631. G-gamma. 1 hit.
    [Graphical view ]
    PRINTSi PR00321. GPROTEING.
    SMARTi SM00224. GGL. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48670. SSF48670. 1 hit.
    PROSITEi PS50058. G_PROTEIN_GAMMA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported and Visual cortexImported.

    Entry informationi

    Entry nameiQ3UGN1_MOUSE
    AccessioniPrimary (citable) accession number: Q3UGN1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)