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Protein

Guanine nucleotide-binding protein subunit gamma

Gene

Gng7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

GO - Molecular functioni

  • signal transducer activity Source: MGI

GO - Biological processi

  • behavioral fear response Source: MGI
  • G-protein coupled receptor signaling pathway Source: InterPro
  • locomotory behavior Source: MGI
  • receptor guanylyl cyclase signaling pathway Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

TransducerUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Guanine nucleotide-binding protein subunit gammaUniRule annotation
Gene namesi
Name:Gng7Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95787. Gng7.

Subcellular locationi

  • Cell membrane UniRule annotation; Lipid-anchor UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

LipoproteinUniRule annotation

Interactioni

Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089936.

Family & Domainsi

Sequence similaritiesi

Belongs to the G protein gamma family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG014983.
KOiK04543.
OMAiSELMNYC.

Family and domain databases

Gene3Di4.10.260.10. 1 hit.
InterProiIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSiPR00321. GPROTEING.
SMARTiSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UGN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTNNVAQA RKLVEQLRIE AGIERIKVSK ASSDLMGYCE QHARNDPLLV
60
GVPASENPFK DKKPCIIL
Length:68
Mass (Da):7,480
Last modified:October 11, 2005 - v1
Checksum:i0F07C667A29ADC07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141541 mRNA. Translation: BAE24725.1.
AK147843 mRNA. Translation: BAE28176.1.
AK158963 mRNA. Translation: BAE34744.1.
RefSeqiNP_001033744.1. NM_001038655.1.
NP_034449.2. NM_010319.3.
UniGeneiMm.222496.

Genome annotation databases

GeneIDi14708.
KEGGimmu:14708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141541 mRNA. Translation: BAE24725.1.
AK147843 mRNA. Translation: BAE28176.1.
AK158963 mRNA. Translation: BAE34744.1.
RefSeqiNP_001033744.1. NM_001038655.1.
NP_034449.2. NM_010319.3.
UniGeneiMm.222496.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089936.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi14708.
KEGGimmu:14708.

Organism-specific databases

CTDi2788.
MGIiMGI:95787. Gng7.

Phylogenomic databases

HOVERGENiHBG014983.
KOiK04543.
OMAiSELMNYC.

Miscellaneous databases

NextBioi286695.
SOURCEiSearch...

Family and domain databases

Gene3Di4.10.260.10. 1 hit.
InterProiIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSiPR00321. GPROTEING.
SMARTiSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported and Visual cortexImported.

Entry informationi

Entry nameiQ3UGN1_MOUSE
AccessioniPrimary (citable) accession number: Q3UGN1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 24, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.