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Protein

Guanine nucleotide-binding protein subunit gamma

Gene

Gng7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransducerUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Guanine nucleotide-binding protein subunit gammaUniRule annotation
Gene namesi
Name:Gng7Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95787. Gng7.

Subcellular locationi

  • Cell membrane UniRule annotation; Lipid-anchor UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

LipoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000048240.

Interactioni

Subunit structurei

G proteins are composed of 3 units, alpha, beta and gamma.SAAS annotation
G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089936.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 68G protein gammaInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the G protein gamma family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4119. Eukaryota.
ENOG41122JF. LUCA.
HOVERGENiHBG014983.
KOiK04543.
OMAiSELMNYC.

Family and domain databases

CDDicd00068. GGL. 1 hit.
Gene3Di4.10.260.10. 1 hit.
InterProiIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSiPR00321. GPROTEING.
SMARTiSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UGN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTNNVAQA RKLVEQLRIE AGIERIKVSK ASSDLMGYCE QHARNDPLLV
60
GVPASENPFK DKKPCIIL
Length:68
Mass (Da):7,480
Last modified:October 11, 2005 - v1
Checksum:i0F07C667A29ADC07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141541 mRNA. Translation: BAE24725.1.
AK147843 mRNA. Translation: BAE28176.1.
AK158963 mRNA. Translation: BAE34744.1.
RefSeqiNP_001033744.1. NM_001038655.1.
NP_034449.2. NM_010319.3.
UniGeneiMm.222496.

Genome annotation databases

GeneIDi14708.
KEGGimmu:14708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141541 mRNA. Translation: BAE24725.1.
AK147843 mRNA. Translation: BAE28176.1.
AK158963 mRNA. Translation: BAE34744.1.
RefSeqiNP_001033744.1. NM_001038655.1.
NP_034449.2. NM_010319.3.
UniGeneiMm.222496.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089936.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi14708.
KEGGimmu:14708.

Organism-specific databases

CTDi2788.
MGIiMGI:95787. Gng7.

Phylogenomic databases

eggNOGiKOG4119. Eukaryota.
ENOG41122JF. LUCA.
HOVERGENiHBG014983.
KOiK04543.
OMAiSELMNYC.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000048240.

Family and domain databases

CDDicd00068. GGL. 1 hit.
Gene3Di4.10.260.10. 1 hit.
InterProiIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSiPR00321. GPROTEING.
SMARTiSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UGN1_MOUSE
AccessioniPrimary (citable) accession number: Q3UGN1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 30, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.