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Protein
Submitted name:

C-terminal binding protein 2, isoform CRA_c

Gene

Ctbp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
C-terminal binding protein 2, isoform CRA_cImported
Gene namesi
Name:Ctbp2Imported
ORF Names:mCG_15820Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1201686. Ctbp2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030970.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000130294.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini44 – 3583152-Hacid_dhInterPro annotationAdd
BLAST
Domaini140 – 3231842-Hacid_dh_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0067. Eukaryota.
COG0111. LUCA.
HOVERGENiHBG001898.
KOiK04496.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UGL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALVDKHKVK RQRLDRICEG IRPQIMNGPL HPRPLVALLD GRDCTVEMPI
60 70 80 90 100
LKDLATVAFC DAQSTQEIHE KVLNEAVGAM MYHTITLTRE DLEKFKALRV
110 120 130 140 150
IVRIGSGYDN VDIKAAGELG IAVCNIPSAA VEETADSTVC HILNLYRRNT
160 170 180 190 200
WLYQALREGT RVQSVEQIRE VASGAARIRG ETLGLIGFGR TGQAVAVRAK
210 220 230 240 250
AFGFSVIFYD PYLQDGIERS LGVQRVYTLQ DLLYQSDCVS LHCNLNEHNH
260 270 280 290 300
HLINDFTIKQ MRQGAFLVNA ARGGLVDEKA LAQALKEGRI RGAALDVHES
310 320 330 340 350
EPFSFAQGPL KDAPNLICTP HTAWYSEQAS LEMREAAATE IRRAITGRIP
360 370 380 390 400
ESLRNCVNKE FFVTSAPWSV IDQQAIHPEL NGATYRYPPG IVGVAPGGLP
410 420 430 440
PAMEGIIPGG IPVTHNLPTV AHPSQAPSPN QPTKHGDNRE HPNEQ
Length:445
Mass (Da):48,957
Last modified:October 11, 2005 - v1
Checksum:i5A81B9D75A9E493B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147871 mRNA. Translation: BAE28193.1.
CH466531 Genomic DNA. Translation: EDL17761.1.
RefSeqiNP_034110.1. NM_009980.4.
XP_006507371.1. XM_006507308.2.
XP_006507372.1. XM_006507309.2.
XP_006507373.1. XM_006507310.2.
XP_006507374.1. XM_006507311.2.
XP_006507375.1. XM_006507312.2.
UniGeneiMm.246240.
Mm.389984.

Genome annotation databases

GeneIDi13017.
KEGGimmu:13017.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147871 mRNA. Translation: BAE28193.1.
CH466531 Genomic DNA. Translation: EDL17761.1.
RefSeqiNP_034110.1. NM_009980.4.
XP_006507371.1. XM_006507308.2.
XP_006507372.1. XM_006507309.2.
XP_006507373.1. XM_006507310.2.
XP_006507374.1. XM_006507311.2.
XP_006507375.1. XM_006507312.2.
UniGeneiMm.246240.
Mm.389984.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000130294.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13017.
KEGGimmu:13017.

Organism-specific databases

CTDi1488.
MGIiMGI:1201686. Ctbp2.

Phylogenomic databases

eggNOGiKOG0067. Eukaryota.
COG0111. LUCA.
HOVERGENiHBG001898.
KOiK04496.

Miscellaneous databases

ChiTaRSiCtbp2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030970.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UGL5_MOUSE
AccessioniPrimary (citable) accession number: Q3UGL5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.