Q3UGB9 (Q3UGB9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAE28290.1

Gene names

Name:

Cdk2 MGI 104772

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Gene Ontology (GO)
Biological_process	Ras protein signal transduction Inferred from electronic annotation. Source: Compara positive regulation of DNA-dependent DNA replication initiation Inferred from genetic interaction PubMed 20215406. Source: MGI positive regulation of cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of transcription, DNA-dependent Inferred from genetic interaction PubMed 16137671. Source: MGI potassium ion transport Inferred from genetic interaction PubMed 16393152. Source: MGI regulation of gene silencing Inferred from electronic annotation. Source: Compara
Cellular_component	Cajal body Inferred from electronic annotation. Source: Compara X chromosome Inferred from direct assay PubMed 17784788. Source: MGI Y chromosome Inferred from direct assay PubMed 17784788. Source: MGI chromosome, telomeric region Inferred from direct assay PubMed 17784788. Source: MGI condensed chromosome Inferred from direct assay PubMed 17784788. Source: MGI cyclin-dependent protein kinase holoenzyme complex Inferred from physical interaction PubMed 12970760. Source: MGI endosome Inferred from electronic annotation. Source: Compara transcription factor complex Inferred from direct assay PubMed 10082561. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cyclin-dependent protein serine/threonine kinase activity Inferred from direct assay PubMed 12970171PubMed 12970760. Source: MGI histone kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3UGB9 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: D806BC2F150AEDFC	FASTA	346	38,978
	10 20 30 40 50 60 MENFQKVEKI GEGTYGVVYK AKNKLTGEVV ALKKIRLDTE TEGVPSTAIR EISLLKELNH 70 80 90 100 110 120 PNIVKLLDVI HTENKLYLVF EFLHQDLKKF MDASALTGIP LPLIKSYLFQ LLQGLAFCHS 130 140 150 160 170 180 HRVLHRDLKP QNLLINAEGS IKLADFGLAR AFGVPVRTYT HEVVTLWYRA PEILLGCKYY 190 200 210 220 230 240 STAVDIWSLG CIFAEMHLVC TQHHAKCCGE HRRNGRHSLC PLCSYLEVAA SQGGGMTAVS 250 260 270 280 290 300 APHPVTRRAL FPGDSEIDQL FRIFRTLGTP DEVVWPGVTS MPDYKPSFPK WARQDFSKVV 310 320 330 340 PPLDEDGRSL LSQMLHYDPN KRISAKAALA HPFFQDVTKP VPHLRL

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[5]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[6]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28290.1 and NOD EMBL BAE32294.1. Tissue: Bone marrow EMBL BAE30846.1, Kidney EMBL BAE27476.1 and Thymus EMBL BAE32294.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK146845 mRNA. Translation: BAE27476.1. AK148017 mRNA. Translation: BAE28290.1. AK151979 mRNA. Translation: BAE30846.1. AK153983 mRNA. Translation: BAE32294.1.
IPI	IPI00124240.
RefSeq	NP_904326.1. NM_183417.3.
UniGene	Mm.111326.
3D structure databases
SMR	Q3UGB9. Positions 1-346.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000026416.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	12566.
KEGG	mmu:12566.
UCSC	uc007hny.2. mouse.
Organism-specific databases
CTD	1017.
MGI	MGI:104772. Cdk2.
Phylogenomic databases
GeneTree	ENSGT00690000101791.
HOVERGEN	HBG014652.
InParanoid	Q3UGB9.
KO	K02206.
OMA	YLEVAAS.
Gene expression databases
Genevestigator	Q3UGB9.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 2 hits. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CDK2. mouse.
NextBio	281656.
SOURCE	Search...

Entry information

Entry name

Q3UGB9_MOUSE

Accession

Primary (citable) accession number: Q3UGB9

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)