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Q3UG37

- Q3UG37_MOUSE

UniProt

Q3UG37 - Q3UG37_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene
Hdac6
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. beta-tubulin binding Source: MGI
  2. histone deacetylase activity Source: MGI
  3. protein binding Source: MGI
  4. tubulin deacetylase activity Source: MGI
  5. ubiquitin binding Source: MGI

GO - Biological processi

  1. aggresome assembly Source: MGI
  2. cellular response to hydrogen peroxide Source: Ensembl
  3. cellular response to misfolded protein Source: MGI
  4. Hsp90 deacetylation Source: MGI
  5. lysosome localization Source: Ensembl
  6. macroautophagy Source: Ensembl
  7. misfolded or incompletely synthesized protein catabolic process Source: Ensembl
  8. negative regulation of microtubule depolymerization Source: MGI
  9. negative regulation of proteolysis Source: Ensembl
  10. peptidyl-lysine deacetylation Source: Ensembl
  11. polyubiquitinated misfolded protein transport Source: Ensembl
  12. positive regulation of chaperone-mediated protein complex assembly Source: Ensembl
  13. positive regulation of epithelial cell migration Source: Ensembl
  14. positive regulation of hydrogen peroxide-mediated programmed cell death Source: Ensembl
  15. positive regulation of receptor biosynthetic process Source: Ensembl
  16. positive regulation of signal transduction Source: Ensembl
  17. protein complex disassembly Source: MGI
  18. protein deacetylation Source: MGI
  19. protein polyubiquitination Source: MGI
  20. regulation of establishment of protein localization Source: MGI
  21. regulation of receptor activity Source: Ensembl
  22. response to growth factor Source: Ensembl
  23. response to toxic substance Source: Ensembl
  24. tubulin deacetylation Source: MGI
  25. ubiquitin-dependent protein catabolic process Source: MGI
  26. ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Hdac6Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1333752. Hdac6.

Subcellular locationi

GO - Cellular componenti

  1. aggresome Source: Ensembl
  2. caveola Source: Ensembl
  3. cell leading edge Source: Ensembl
  4. cytoplasm Source: MGI
  5. dynein complex Source: Ensembl
  6. histone deacetylase complex Source: Ensembl
  7. microtubule Source: Ensembl
  8. nucleus Source: MGI
  9. perinuclear region of cytoplasm Source: Ensembl
  10. protein complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ3UG37.

Structurei

3D structure databases

ProteinModelPortaliQ3UG37.
SMRiQ3UG37. Positions 84-438, 479-834.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000004769.
HOVERGENiHBG051894.
KOiK11407.

Family and domain databases

Gene3Di3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 2 hits.
[Graphical view]
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Fragment.

Q3UG37-1 [UniParc]FASTAAdd to Basket

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MTSTGQDSST RQRKSRHNPQ SPLQESSATL KRGGKKCAVP HSSPNLAEVK     50
KKGKMKKLSQ PAEEDLVVGL QGLDLNPETR VPVGTGLVFD EQLNDFHCLW 100
DDSFPESPER LHAIREQLIL EGLLGRCVSF QARFAEKEEL MLVHSLEYID 150
LMETTQYMNE GELRVLAETY DSVYLHPNSY SCACLATGSV LRLVDALMGA 200
EIRNGMAVIR PPGHHAQHNL MDGYCMFNHL AVAARYAQKK HRIQRVLIVD 250
WDVHHGQGTQ FIFDQDPSVL YFSIHRYEHG RFWPHLKASN WSTIGFGQGQ 300
GYTINVPWNQ TGMRDADYIA AFLHILLPVA SEFQPQLVLV AAGFDALHGD 350
PKGEMAATPA GFAHLTHLLM GLAGGKLILS LEGGYNLRAL AKGVSASLHT 400
LLGDPCPMLE SCVVPCASAQ TSIYCTLEAL EPFWEVLERS VETQEEDEVE 450
EAVLEEEEEE GGWEATALPM DTWPLLQNRT GLVYDEKMMS HCNLWDNHHP 500
ETPQRILRIM CHLEEVGLAA RCLILPARPA LDSELLTCHS AEYVEHLRTT 550
EKMKTRDLHR EGANFDSIYI CPSTFACAKL ATGAACRLVE AVLSGEVLNG 600
IAVVRPPGHH AEPNAACGFC FFNSVAVAAR HAQIIAGRAL RILIVDWDVH 650
HGNGTQHIFE DDPSVLYVSL HRYDRGTFFP MGDEGASSQV GRDAGIGFTV 700
NVPWNGPRMG DADYLAAWHR LVLPIAYEFN PELVLISAGF DAAQGDPLGG 750
CQVTPEGYAH LTHLLMGLAG GRIILILEGG YNLASISESM AACTHSLLGD 800
PPPQLTLLRP PQSGALVSIS EVIQVHRKYW RSLRLMKMED KEECSSSRLV 850
IKKLPPTASP VSAKEMTTPK GKVPEESVRK TIAALPGKES TLGQAKSKMA 900
KAVLAQGQSS EQAAKGTTLD LATSKETVGG ATTDLWASAA APENFPNQTT 950
SVEALGETEP TPPASHTNKQ TTGASPLQGV TAQQSLQLGV LSTLELSREA 1000
EEAHDSEEG 1009
Length:1,009
Mass (Da):110,243
Last modified:October 11, 2005 - v1
Checksum:iF91A3A0E0DA8E91F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1009 – 10091Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK148144 mRNA. Translation: BAE28372.1.
RefSeqiNP_034543.3. NM_010413.3.
UniGeneiMm.29854.

Genome annotation databases

GeneIDi15185.
KEGGimmu:15185.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK148144 mRNA. Translation: BAE28372.1 .
RefSeqi NP_034543.3. NM_010413.3.
UniGenei Mm.29854.

3D structure databases

ProteinModelPortali Q3UG37.
SMRi Q3UG37. Positions 84-438, 479-834.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 15185.
KEGGi mmu:15185.

Organism-specific databases

CTDi 10013.
MGIi MGI:1333752. Hdac6.

Phylogenomic databases

HOGENOMi HOG000004769.
HOVERGENi HBG051894.
KOi K11407.

Miscellaneous databases

NextBioi 287707.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3UG37.

Family and domain databases

Gene3Di 3.40.800.20. 2 hits.
InterProi IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 2 hits.
[Graphical view ]
PRINTSi PR01270. HDASUPER.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3UG37_MOUSE
AccessioniPrimary (citable) accession number: Q3UG37
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 9, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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