Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Receptor protein serine/threonine kinase

Gene

Bmpr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, ReceptorSAAS annotation, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Receptor protein serine/threonine kinaseSAAS annotation (EC:2.7.11.30SAAS annotation)
Gene namesi
Name:Bmpr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1095407. Bmpr2.

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ3UG09.
PeptideAtlasiQ3UG09.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 234Protein kinaseInterPro annotationAdd BLAST234

Sequence similaritiesi

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG3653. Eukaryota.
ENOG410XS2Z. LUCA.
HOVERGENiHBG050705.
KOiK04671.

Family and domain databases

InterProiView protein in InterPro
IPR015770. BMPR2.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR000333. TGFB_receptor.
PANTHERiPTHR23255. PTHR23255. 1 hit.
PTHR23255:SF63. PTHR23255:SF63. 1 hit.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q3UG09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GRMEYLLVME YYPNGSLCKY LSLHTSDWVS SCRLAHSVTR GLAYLHTELP
60 70 80 90 100
RGDHYKPAIS HRDLNSRNVL VKNDGACVIS DFGLSMRLTG NRLVRPGEED
110 120 130 140 150
NAAISEVGTI RYMAPEVLEG AVNLRDCESA LKQVDMYALG LIYWEVFMRC
160 170 180 190 200
TDLFPGESVP DYQMAFQTEV GNHPTFEDMQ VLVSREKQRP KFPEAWKENS
210 220 230 240 250
LAVRSLKETI EDCWDQDAEA RLTAQCAEER MAELMMIWER NKSVSPTVNP
260 270 280 290 300
MSTAMQNERN LSHNRRVPKI GPYPDYSSSS YIEDSIHHTD SIVKNISSEH
310 320 330 340 350
SMSSTPLTIG EKNRNSINYE RQQAQARIPS PETSVTSLST NTTTTNTTGL
360 370 380 390 400
TPSTGMTTIS EMPYPDETHL HATNVAQSIG PTPVCLQLTE EDLETNKLDP
410 420 430 440 450
KEVDKNLKES SDENLMEHSL KQFSGPDPLS STSSSLLYPL IKLAVEVTGQ
460 470 480 490 500
QDFTQAANGQ ACLIPDVPPA QIYPLPKQQN LPKRPTSLPL NTKNSTKEPR
510 520 530 540 550
LKFGNKHKSN LKQVETGVAK MNTINAAEPH VVTVTMNGVA GRSHNVNSHA
560 570 580 590 600
ATTQYANGAV PAGQAANIVA HRSQEMLQNQ FIGEDTRLNI NSSPDEHEPL
610 620 630 640 650
LRREQQAGHD EGVLDRLVDR RERPLEGGRT NSNNNNSNPC SEQDILTQGV
660 670 680 690 700
TSTAADPGPS KPRRAQRPNS LDLSATNILD GSSIQIGEST QDGKSGSGEK
710 720 730 740 750
IKRRVKTPYS LKRWRPSTWV ISTEPLDCEV NNNGSDRAVH SKSSTAVYLA
760
EGGTATTTVS KDIGMNCL
Length:768
Mass (Da):84,871
Last modified:October 11, 2005 - v1
Checksum:iB3C546654C8A0D7D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK148180 mRNA. Translation: BAE28400.1.
RefSeqiNP_031587.1. NM_007561.4.
UniGeneiMm.391654.
Mm.7106.

Genome annotation databases

GeneIDi12168.
KEGGimmu:12168.

Similar proteinsi

Entry informationi

Entry nameiQ3UG09_MOUSE
AccessioniPrimary (citable) accession number: Q3UG09
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)