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Q3UF49

- Q3UF49_MOUSE

UniProt

Q3UF49 - Q3UF49_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Atp1a1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ADP binding Source: Ensembl
    2. ATP binding Source: Ensembl
    3. phosphatase activity Source: MGI
    4. potassium ion binding Source: Ensembl
    5. protein binding Source: MGI
    6. sodium:potassium-exchanging ATPase activity Source: MGI
    7. sodium ion binding Source: Ensembl

    GO - Biological processi

    1. cellular response to mechanical stimulus Source: Ensembl
    2. dephosphorylation Source: GOC
    3. membrane hyperpolarization Source: Ensembl
    4. negative regulation of glucocorticoid biosynthetic process Source: MGI
    5. negative regulation of heart contraction Source: MGI
    6. positive regulation of heart contraction Source: MGI
    7. positive regulation of striated muscle contraction Source: MGI
    8. potassium ion import Source: Ensembl
    9. regulation of blood pressure Source: MGI
    10. regulation of cardiac muscle cell contraction Source: Ensembl
    11. regulation of sodium ion transport Source: Ensembl
    12. regulation of the force of heart contraction Source: MGI
    13. response to drug Source: MGI
    14. sodium ion transmembrane transport Source: GOC

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Atp1a1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:88105. Atp1a1.

    Subcellular locationi

    GO - Cellular componenti

    1. apical plasma membrane Source: MGI
    2. basolateral plasma membrane Source: MGI
    3. caveola Source: Ensembl
    4. endoplasmic reticulum Source: Ensembl
    5. endosome Source: Ensembl
    6. Golgi apparatus Source: Ensembl
    7. plasma membrane Source: MGI
    8. protein complex Source: MGI
    9. sarcolemma Source: MGI
    10. sodium:potassium-exchanging ATPase complex Source: Ensembl

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3UF49.

    Expressioni

    Gene expression databases

    ArrayExpressiQ3UF49.
    BgeeiQ3UF49.
    GenevestigatoriQ3UF49.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3UF49.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG004298.
    InParanoidiQ3UF49.

    Family and domain databases

    Gene3Di1.20.1110.10. 1 hit.
    InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
    IPR023298. ATPase_P-typ_TM_dom.
    IPR001757. Cation_transp_P_typ_ATPase.
    IPR023214. HAD-like_dom.
    [Graphical view]
    PfamiPF00689. Cation_ATPase_C. 1 hit.
    PF00702. Hydrolase. 1 hit.
    [Graphical view]
    PRINTSiPR00119. CATATPASE.
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01494. ATPase_P-type. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q3UF49-1 [UniParc]FASTAAdd to Basket

    « Hide

    GDHPITAKAI AKGVGIISEG NETVEDIAAR LNIPVNQVNP RDAKACVVHG    50
    SDLKDMTSEE LDDILRYHTE IVFARTSPQQ KLIIVEGCQR QGAIVAVTGD 100
    GVNDSPALKK ADIGVAMGIV GSDVSKQAAD MILLDDNFAS IVTGVEEGRL 150
    IFDNLKKSIA YTLTSNIPEI TPFLIFIIAN IPLPLGTVTI LCIDLGTDMV 200
    PAISLAYEQA ESDIMKRQPR NPKTDKLVNE RLISMAYGQI GMIQALGGFF 250
    TYFVILAENG FLPFHLLGIR ETWDDRWVND VEDSYGQQWT YEQRKIVEFT 300
    CHTAFFVSIV VVQWADLVIC KTRRNSVFQQ GMKNKILIFG LFEETALAAF 350
    LSYCPGMGAA LRMYPLKPTW WFCAFPYSLL IFVYDEVRKL IIRRRPGGWV 400
    EKETYY 406
    Length:406
    Mass (Da):45,361
    Last modified:October 11, 2005 - v1
    Checksum:iD0D8A6024BCB012C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK148989 mRNA. Translation: BAE28712.1.
    UniGeneiMm.280103.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK148989 mRNA. Translation: BAE28712.1 .
    UniGenei Mm.280103.

    3D structure databases

    ProteinModelPortali Q3UF49.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q3UF49.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:88105. Atp1a1.

    Phylogenomic databases

    HOVERGENi HBG004298.
    InParanoidi Q3UF49.

    Miscellaneous databases

    ChiTaRSi ATP1A1. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3UF49.
    Bgeei Q3UF49.
    Genevestigatori Q3UF49.

    Family and domain databases

    Gene3Di 1.20.1110.10. 1 hit.
    InterProi IPR006068. ATPase_P-typ_cation-transptr_C.
    IPR023298. ATPase_P-typ_TM_dom.
    IPR001757. Cation_transp_P_typ_ATPase.
    IPR023214. HAD-like_dom.
    [Graphical view ]
    Pfami PF00689. Cation_ATPase_C. 1 hit.
    PF00702. Hydrolase. 1 hit.
    [Graphical view ]
    PRINTSi PR00119. CATATPASE.
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01494. ATPase_P-type. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.

    Entry informationi

    Entry nameiQ3UF49_MOUSE
    AccessioniPrimary (citable) accession number: Q3UF49
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)