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Q3UEW8

- Q3UEW8_MOUSE

UniProt

Q3UEW8 - Q3UEW8_MOUSE

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Protein
Submitted name: Putative uncharacterized protein
Gene
Pdpk1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 3-phosphoinositide-dependent protein kinase activity Source: MGI
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. activation of protein kinase B activity Source: Ensembl
  2. cellular response to insulin stimulus Source: Ensembl
  3. extrinsic apoptotic signaling pathway Source: Ensembl
  4. focal adhesion assembly Source: Ensembl
  5. hyperosmotic response Source: MGI
  6. intracellular signal transduction Source: Ensembl
  7. negative regulation of protein kinase activity Source: Ensembl
  8. negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  9. peptidyl-threonine phosphorylation Source: Ensembl
  10. positive regulation of establishment of protein localization to plasma membrane Source: Ensembl
  11. regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
  12. signal transduction Source: MGI
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Pdpk1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1338068. Pdpk1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. cytoplasmic membrane-bounded vesicle Source: MGI
  3. cytosol Source: Ensembl
  4. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ3UEW8.
BgeeiQ3UEW8.
GenevestigatoriQ3UEW8.

Structurei

3D structure databases

ProteinModelPortaliQ3UEW8.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000233026.
HOVERGENiHBG098357.
InParanoidiQ3UEW8.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3UEW8-1 [UniParc]FASTAAdd to Basket

« Hide

MARTTSQLYD AVPIQSSVVL CSCPSPSMVR SQTEPGSSPG IPSGVSRQGS    50
TMDGTTAEAR PSTNPLQQHP AQLPPQPRKK RPEDFKFGKI LGEGSFSTVV 100
LARELATSRE YAIKILEKRH IIKENKVPYV TRERDVMSRL DHPFFVKLYF 150
TFQDDEKLYF GLSYAKNGEL LKYIRKIGSF DETCTRFYTA EIVSALEYLH 200
GKGIIHRDLK PENILLNEDM HIQITDFGTA KVLSPESKQA RANSFVGTAQ 250
YVSPELLTEK SACKSSDLWA LGCIIYQLVA GLPPFRAGNE YLIFQKIIKL 300
EYHFPEKFFP KARDLVEKLL VLDATKRLGC EEMEGYGPLK AHPFFETITW 350
ENLHQQTPPK LTAYLPAMSE DDEDCYGNYD NLLSQFGFMQ VSSSSSSHSL 400
STVETSLPQR SGSNIEQYIH DLDTNSFELD LQFS 434
Length:434
Mass (Da):48,960
Last modified:October 11, 2005 - v1
Checksum:i161630FB56FC793F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei434 – 4341Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK149289 mRNA. Translation: BAE28793.1.
UniGeneiMm.10504.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK149289 mRNA. Translation: BAE28793.1 .
UniGenei Mm.10504.

3D structure databases

ProteinModelPortali Q3UEW8.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1338068. Pdpk1.

Phylogenomic databases

HOGENOMi HOG000233026.
HOVERGENi HBG098357.
InParanoidi Q3UEW8.

Miscellaneous databases

ChiTaRSi PDPK1. mouse.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q3UEW8.
Bgeei Q3UEW8.
Genevestigatori Q3UEW8.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: RetinaImported.

Entry informationi

Entry nameiQ3UEW8_MOUSE
AccessioniPrimary (citable) accession number: Q3UEW8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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