Skip Header

Contribute Send feedback
Read comments (0) or add your own

Unreviewed, UniProtKB/TrEMBL Q3UEI4 (Q3UEI4_MOUSE)

Last modified February 9, 2010. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Hide | Top

Names and origin

Protein namesRecommended name:
    Pyruvate kinase RuleBase RU000504V4
    EC=2.7.1.40 RuleBase RU000504V4
Gene names
Name: Pklr MGI 97604
OrganismMus musculus (Mouse) EMBL BAE28927.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Hide | Top

Protein attributes

Sequence length546 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

Hide | Top

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate. RuleBase RU000504V4

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. RuleBase RU000504V4

Sequence similarities

Belongs to the pyruvate kinase family.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAE28927.1

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q3UEI4-1 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 7F0BE99BB6E036C1

FASTA54659,052
        10         20         30         40         50         60 
GSSMEGPAGY LRRASVAQLT QELGTAFFQQ QQLPAAMADT FLEHLCLLDI DSEPVAARST 

        70         80         90        100        110        120 
SIIATIGPAS RSVDRLKEMI KAGMNIARLN FSHGSHEYHA ESIANIREAA ESFATSPLSY 

       130        140        150        160        170        180 
RPVAIALDTK GPEIRTGVLQ GGPESEVEIV KGSQVLVTVD PKFRTRGDAK TVWVDYHNIT 

       190        200        210        220        230        240 
QVVAVGGRIY IDDGLISLVV RKIGPEGLVT EVEHGGFLGN RKGVNLPNAE VDLPGLSEQD 

       250        260        270        280        290        300 
LLDLRFGVEH NVDIIFASFV RKASDVVAVR DALGPEGRGI KIISKIENHE GVKKFDEILE 

       310        320        330        340        350        360 
VSDGIMVARG DLGIEIPAEK VFLAQKMMIG RCNLAGKPVV CATQMLESMI TKARPTRAET 

       370        380        390        400        410        420 
SDVANAVLDG ADCIMLSGET AKGSFPVEAV KMQHAIAREA EAAVYHRQLF EELRRAAPLS 

       430        440        450        460        470        480 
RDPTEVTAIG AVEASFKCCA AAIIVLTKTG RSAQLLSRYR PRAAVIAVTR SAQAARQVHL 

       490        500        510        520        530        540 
SRGVFPLLYR EPPEAVWADD VDRRVQFGIE SGKLRGFLRV GDLVIVVTGW RPGSGYTNIM 


RVLTIS

« Hide

Hide | Top

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J EMBL BAE28927.1.
Tissue: Liver EMBL BAE28927.1.
+Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK149508 mRNA. Translation: BAE28927.1.
IPIIPI00775829.
RefSeqNP_001093249.1.
NP_038659.2.
UniGeneMm.383180

3D structure databases

SMRQ3UEI4. Positions 29-545.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3UEI4.

Genome annotation databases

EnsemblENSMUST00000107482; ENSMUSP00000103106; ENSMUSG00000041237; Mus musculus. [Genome view]
GeneID18770.
KEGGmmu:18770.
UCSCuc008pxp.1. mouse.

Organism-specific databases

CTD18770.
MGIMGI:97604. Pklr.

Phylogenomic databases

HOVERGENQ3UEI4.
PhylomeDBQ3UEI4.

Gene expression databases

ArrayExpressQ3UEI4.
BgeeQ3UEI4.
GenevestigatorQ3UEI4.

Family and domain databases

InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase_cat.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR011037. Pyrv_Knase_b-brl-like.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C-like.
[Graphical view]
Gene3DG3DSA:3.20.20.60. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
G3DSA:3.40.1380.20. Pyrv_Knase_a/b. 1 hit.
PANTHERPTHR11817. Pyruvate_kinase. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio294995.
SOURCESearch...

Hide | Top

Entry information

Entry nameQ3UEI4_MOUSE
AccessionPrimary (citable) accession number: Q3UEI4
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information