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Protein
Submitted name:

Putative uncharacterized protein

Gene

Pah

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Fe2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi285 – 2851IronUniRule annotation
Metal bindingi290 – 2901IronUniRule annotation
Metal bindingi329 – 3291IronUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

IronUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:PahImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97473. Pah.

PTM / Processingi

Proteomic databases

PaxDbiQ3UEH8.
PRIDEiQ3UEH8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020051.
GenevisibleiQ3UEH8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020241.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 11479ACTInterPro annotationAdd
BLAST
Domaini106 – 451346BH4_AAA_HYDROXYL_2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3820. Eukaryota.
COG3186. LUCA.
HOVERGENiHBG006841.
KOiK00500.

Family and domain databases

Gene3Di1.10.800.10. 1 hit.
InterProiIPR002912. ACT_dom.
IPR001273. ArAA_hydroxylase.
IPR018301. ArAA_hydroxylase_Fe/CU_BS.
IPR019774. Aromatic-AA_hydroxylase_C.
IPR005961. Phe-4-hydroxylase_tetra.
IPR019773. Tyrosine_3-monooxygenase-like.
[Graphical view]
PANTHERiPTHR11473. PTHR11473. 1 hit.
PfamiPF01842. ACT. 1 hit.
PF00351. Biopterin_H. 1 hit.
[Graphical view]
PIRSFiPIRSF000336. TH. 1 hit.
PRINTSiPR00372. FYWHYDRXLASE.
SUPFAMiSSF56534. SSF56534. 1 hit.
TIGRFAMsiTIGR01268. Phe4hydrox_tetr. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
PS00367. BH4_AAA_HYDROXYL_1. 1 hit.
PS51410. BH4_AAA_HYDROXYL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UEH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVVLENGV LSRKLSDFGQ ETSYIEDNSN QNGAVSLIFS LKEEVGALAK
60 70 80 90 100
VLRLFEENEI NLTHIESRPS RLNKDEYEFF TYLDKRSKPV LGSIIKSLRN
110 120 130 140 150
DIGATVHELS RDKEKNTVPW FPRTIQELDR FANQILSYGA ELDADHPGFK
160 170 180 190 200
DPVYRARRKQ FADIAYNYRH GQPIPRVEYT EEERKTWGTV FRTLKALYKT
210 220 230 240 250
HACYEHNHIF PLLEKYCGFR EDNIPQLEDV SQFLQTCTGF RLRPVAGLLS
260 270 280 290 300
SRDFLGGLAF RVFHCTQYIR HGSKPMYTPE PDICHELLGH VPLFSDRSFA
310 320 330 340 350
QFSQEIGLAS LGAPEYIEKL ATIYWFTVEF GLCKEGDSIK AYGAGLLSSF
360 370 380 390 400
GELQYCLSDK PKLLPLELEK TACQEYTVTE FQPLYYVAES FNDAKEKVRT
410 420 430 440 450
FAATIPRPFS VRYDPYTQRV EVLDNTQQLK ILADSINSEV GILCHALQKI

KS
Length:452
Mass (Da):51,785
Last modified:October 11, 2005 - v1
Checksum:iC9772629DACFB1FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK149519 mRNA. Translation: BAE28933.1.
RefSeqiNP_032803.2. NM_008777.3.
UniGeneiMm.263539.

Genome annotation databases

GeneIDi18478.
KEGGimmu:18478.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK149519 mRNA. Translation: BAE28933.1.
RefSeqiNP_032803.2. NM_008777.3.
UniGeneiMm.263539.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020241.

Proteomic databases

PaxDbiQ3UEH8.
PRIDEiQ3UEH8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi18478.
KEGGimmu:18478.

Organism-specific databases

CTDi5053.
MGIiMGI:97473. Pah.

Phylogenomic databases

eggNOGiKOG3820. Eukaryota.
COG3186. LUCA.
HOVERGENiHBG006841.
KOiK00500.

Miscellaneous databases

ChiTaRSiPah. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020051.
GenevisibleiQ3UEH8. MM.

Family and domain databases

Gene3Di1.10.800.10. 1 hit.
InterProiIPR002912. ACT_dom.
IPR001273. ArAA_hydroxylase.
IPR018301. ArAA_hydroxylase_Fe/CU_BS.
IPR019774. Aromatic-AA_hydroxylase_C.
IPR005961. Phe-4-hydroxylase_tetra.
IPR019773. Tyrosine_3-monooxygenase-like.
[Graphical view]
PANTHERiPTHR11473. PTHR11473. 1 hit.
PfamiPF01842. ACT. 1 hit.
PF00351. Biopterin_H. 1 hit.
[Graphical view]
PIRSFiPIRSF000336. TH. 1 hit.
PRINTSiPR00372. FYWHYDRXLASE.
SUPFAMiSSF56534. SSF56534. 1 hit.
TIGRFAMsiTIGR01268. Phe4hydrox_tetr. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
PS00367. BH4_AAA_HYDROXYL_1. 1 hit.
PS51410. BH4_AAA_HYDROXYL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UEH8_MOUSE
AccessioniPrimary (citable) accession number: Q3UEH8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.