Q3UEH4 (Q3UEH4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAE28937.1

Gene names

Name:

Pklr MGI 97604

Organism

Mus musculus (Mouse) EMBL BAE28937.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	543 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW response to other organism Inferred from mutant phenotype. Source: MGI
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro potassium ion binding Inferred from electronic annotation. Source: InterPro pyruvate kinase activity Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3UEH4 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: D2965CC5F566E0F6	FASTA	543	58,849
	10 20 30 40 50 60 MEGPAGYLRR ASVAQLTQEL GTAFFQQQQL PAAMADTFLE HLCLLDIDSE PVAARSTSII 70 80 90 100 110 120 ATIGPASRSV DRLKEMIKAG MNIARLNFSH GSHEYHAESI ANIREAAESF ATSPLSYRPV 130 140 150 160 170 180 AIALDTKGPE IRTGVLQGGP ESEVEIVKGS QVLVTVDPKF RTRGDAKTVW VDYHNITQVV 190 200 210 220 230 240 AVGGRIYIDD GLISLVVRKI GPEGLVTEVE HGGFLGNRKG VNLPNAEVDL PGLSEQDLLD 250 260 270 280 290 300 LRFGVEHNVD IIFASFVRKA SDVVAVRDAL GPEGRGIKII SKIENHEGVK KFDEILEVSD 310 320 330 340 350 360 GIMVARGDLG IEIPAEKVFL AQKMMIGRCN LAGKPVVCAT QMLESMITKA RPTRAETSDV 370 380 390 400 410 420 ANAVLDGADC IMLSGETAKG SFPVEAVKMQ HAIVREAEAA VYHRQLFEEL RRAAPLSRDP 430 440 450 460 470 480 TEVTAIGAVE ASFKCCAAAI IVLTKTGRSA QLLSRYRPRA AVIAVTRSAQ AARQVHLSRG 490 500 510 520 530 540 VFPLLYREPP EAVWADDVDR RVQFGIESGK LRGFLRVGDL VIVVTGWRPG SGYTNIMRVL TIS

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed: 10349636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[2]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed: 16141073] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[3]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[4]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[6]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed: 11042159] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[7]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed: 11076861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
[8]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE28937.1. Tissue: Liver EMBL BAE28937.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK149524 mRNA. Translation: BAE28937.1.
IPI	IPI00133605.
RefSeq	NP_001093249.1. NM_001099779.1. NP_038659.2. NM_013631.2.
UniGene	Mm.383180.
3D structure databases
ProteinModelPortal	Q3UEH4.
SMR	Q3UEH4. Positions 26-542.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3UEH4.
Proteomic databases
PRIDE	Q3UEH4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	18770.
KEGG	mmu:18770.
Organism-specific databases
CTD	5313.
MGI	MGI:97604. Pklr.
Phylogenomic databases
HOVERGEN	HBG000941.
Gene expression databases
ArrayExpress	Q3UEH4.
Genevestigator	Q3UEH4.
Family and domain databases
InterPro	IPR001697. Pyr_Knase. IPR015813. Pyrv/PenolPyrv_Kinase. IPR011037. Pyrv_Knase-like_insert_dom. IPR015794. Pyrv_Knase_a/b. IPR018209. Pyrv_Knase_AS. IPR015793. Pyrv_Knase_brl. IPR015795. Pyrv_Knase_C. IPR015806. Pyrv_Knase_insert_dom. [Graphical view]
Gene3D	G3DSA:2.40.33.10. PK_B_barrel_like. 1 hit. G3DSA:3.20.20.60. Pyrv/PenolPyrv_Kinase_cat. 2 hits. G3DSA:3.40.1380.20. Pyrv_Knase_a/b. 1 hit.
KO	K12406.
PANTHER	PTHR11817. Pyruvate_kinase. 1 hit.
Pfam	PF00224. PK. 1 hit. PF02887. PK_C. 1 hit. [Graphical view]
PRINTS	PR01050. PYRUVTKNASE.
SUPFAM	SSF50800. PK_B_barrel_like. 1 hit. SSF52935. Pyruvate_kinase. 1 hit. SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMs	TIGR01064. Pyruv_kin. 1 hit.
PROSITE	PS00110. PYRUVATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q3UEH4_MOUSE

Accession

Primary (citable) accession number: Q3UEH4

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)