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Protein
Submitted name:

Cathepsin C, isoform CRA_b

Gene

Ctsc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cathepsin C, isoform CRA_bImported
Gene namesi
Name:CtscImported
ORF Names:mCG_113517Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:109553 Ctsc

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24UniRule annotationAdd BLAST24
ChainiPRO_501420583025 – 462UniRule annotationAdd BLAST438

Proteomic databases

MaxQBiQ3UBY5

Expressioni

Gene expression databases

BgeeiENSMUSG00000030560
ExpressionAtlasiQ3UBY5 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3UBY5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 457Pept_C1InterPro annotationAdd BLAST228

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1543 Eukaryota
COG4870 LUCA
HOVERGENiHBG005248
KOiK01275
OMAiYDDFLHY
OrthoDBiEOG091G06TT

Family and domain databases

Gene3Di2.40.128.80, 1 hit
InterProiView protein in InterPro
IPR014882 CathepsinC_exc
IPR036496 CathepsinC_exc_dom_sf
IPR025661 Pept_asp_AS
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF08773 CathepsinC_exc, 1 hit
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00645 Pept_C1, 1 hit
SUPFAMiSSF75001 SSF75001, 1 hit
PROSITEiView protein in PROSITE
PS00640 THIOL_PROTEASE_ASN, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

Q3UBY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPWTHSLRA VLLLVLLGVC TVRSDTPANC TYPDLLGTWV FQVGPRSSRS
60 70 80 90 100
DINCSVMEAT EEKVVVHLKK LDTAYDELGN SGHFTLIYNQ GFEIVLNDYK
110 120 130 140 150
WFAFFKYEVR GHTAISYCHE TMTGWVHDVL GRNWACFVGK KVESHIEKVN
160 170 180 190 200
MNAAHLGGLQ ERYSERLYTH NHNFVKAINT VQKSWTATAY KEYEKMSLRD
210 220 230 240 250
LIRRSGHSQR IPRPKPAPMT DEIQQQILNL PESWDWRNVQ GVNYVSPVRN
260 270 280 290 300
QESCGSCYSF ASMGMLEARI RILTNNSQTP ILSPQEVVSC SPYAQGCDGG
310 320 330 340 350
FPYLIAGKYA QDFGVVEESC FPYTAKDSPC KPRENCLRYY SSDYYYVGGF
360 370 380 390 400
YGGCNEALMK LELVKHGPMA VAFEVHDDFL HYHSGIYHHT GLSDPFNPFE
410 420 430 440 450
LTNHAVLLVG YGRDPVTGIE YWIIKNSWGS NWGESGYFRI RRGTDECAIE
460
SIAVAAIPIP KL
Length:462
Mass (Da):52,376
Last modified:October 11, 2005 - v1
Checksum:i56574B38D7DF4710
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146858 mRNA Translation: BAE27487.1
AK150761 mRNA Translation: BAE29829.1
CH466543 Genomic DNA Translation: EDL06796.1
RefSeqiNP_001298719.1, NM_001311790.1
NP_034112.3, NM_009982.5
UniGeneiMm.322945
Mm.483300
Mm.89295

Genome annotation databases

GeneIDi13032
KEGGimmu:13032

Similar proteinsi

Entry informationi

Entry nameiQ3UBY5_MOUSE
AccessioniPrimary (citable) accession number: Q3UBY5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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