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Unreviewed, UniProtKB/TrEMBL Q3UB40 (Q3UB40_MOUSE)

Last modified January 19, 2010. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Putative uncharacterized protein EMBL BAE30124.1
Gene names
Name: Nfkbia MGI 104741
OrganismMus musculus (Mouse) EMBL BAE30124.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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Ontologies

Keywords
   DomainANK repeat RuleBase RU003321V2
Repeat RuleBase RU003536V1
Gene Ontology (GO)
   Biological processcytoplasmic sequestering of NF-kappaB

Inferred from electronic annotation. Source: Compara

lipopolysaccharide-mediated signaling pathway

Inferred from direct assay. Source: MGI

negative regulation of Notch signaling pathway

Inferred from mutant phenotype. Source: MGI

negative regulation of lipid storage

Inferred from electronic annotation. Source: Compara

negative regulation of macrophage derived foam cell differentiation

Inferred from electronic annotation. Source: Compara

negative regulation of myeloid cell differentiation

Inferred from mutant phenotype. Source: MGI

nucleotide-binding oligomerization domain containing 1 signaling pathway

Inferred from direct assay. Source: MGI

nucleotide-binding oligomerization domain containing 2 signaling pathway

Inferred from direct assay. Source: MGI

positive regulation of cellular protein metabolic process

Inferred from electronic annotation. Source: Compara

positive regulation of cholesterol efflux

Inferred from electronic annotation. Source: Compara

positive regulation of gene-specific transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

protein import into nucleus, translocation

Inferred from direct assay. Source: MGI

regulation of cell proliferation

Inferred from direct assay. Source: MGI

response to exogenous dsRNA

Inferred from direct assay. Source: MGI

response to lipopolysaccharide

Inferred from direct assay. Source: MGI

response to muramyl dipeptide

Inferred from direct assay. Source: MGI

toll-like receptor 4 signaling pathway

Inferred from direct assay. Source: MGI

   Cellular componentcytosol

Inferred from direct assay. Source: MGI

nucleus

Inferred from direct assay. Source: MGI

   Molecular functionNF-kappaB binding

Inferred from electronic annotation. Source: Compara

heat shock protein binding

Inferred from electronic annotation. Source: Compara

identical protein binding

Inferred from electronic annotation. Source: Compara

nuclear localization sequence binding

Inferred from electronic annotation. Source: Compara

protein complex binding

Inferred from electronic annotation. Source: Compara

ubiquitin protein ligase binding

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
Q3UB40-1 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: E1783F8E1BA93813

FASTA31435,071
        10         20         30         40         50         60 
MFQPAGHGQD WAMEGPRDGL KKERLVDDRH DSGLDSMKDE EYEQMVKELR EIRLQPQEAP 

        70         80         90        100        110        120 
LAAEPWKQQL TEDGDSFLHL AIIHEEKPLT MEVIGQVKGD LAFLNFQNNL QQTPLHLAVI 

       130        140        150        160        170        180 
TNQPGIAEAL LKAGCDPELR DFRGNTPLHL ACEQGCLASV AVLTQTCTPQ HLHSVLQATN 

       190        200        210        220        230        240 
YNGHTCLHLA SIHGYLAIVE HLVTLGADVN AQEPCNGRTA LHLAVDLQNP DLVSLLLKCG 

       250        260        270        280        290        300 
ADVNRVTYQG YSPYQLTWGR PSTRIQQQLG QLTLENLQML PESEDEESYD TESEFTEDEL 

       310 
PYDDCVFGGQ RLTL

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References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J EMBL BAE30124.1.
Tissue: Bone marrow EMBL BAE30124.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK151115 mRNA. Translation: BAE30124.1.
IPIIPI00331017.
RefSeqNP_035037.2.
UniGeneMm.170515

3D structure databases

SMRQ3UB40. Positions 70-281.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3UB40.

Proteomic databases

PRIDEQ3UB40.

Genome annotation databases

EnsemblENSMUST00000021413; ENSMUSP00000021413; ENSMUSG00000021025; Mus musculus. [Genome view]
GeneID18035.
KEGGmmu:18035.
UCSCuc007nor.1. mouse.

Organism-specific databases

CTD18035.
MGIMGI:104741. Nfkbia.

Phylogenomic databases

HOVERGENQ3UB40.
InParanoidQ3UB40.
OMAHLAVITD.
PhylomeDBQ3UB40.

Gene expression databases

ArrayExpressQ3UB40.
BgeeQ3UB40.
GenevestigatorQ3UB40.

Family and domain databases

InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR015681. NF_kB_inhbitor.
[Graphical view]
Gene3DG3DSA:1.25.40.20. ANK. 1 hit.
PANTHERPTHR18958:SF236. NF_kB_inhbitor. 1 hit.
PfamPF00023. Ank. 3 hits.
[Graphical view]
SMARTSM00248. ANK. 5 hits.
[Graphical view]
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

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Entry information

Entry nameQ3UB40_MOUSE
AccessionPrimary (citable) accession number: Q3UB40
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: January 19, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information