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Protein
Submitted name:

Heat shock protein 90kDa beta (Grp94), member 1

Gene

Hsp90b1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Stress responseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heat shock protein 90kDa beta (Grp94), member 1Imported
Gene namesi
Name:Hsp90b1Imported
Synonyms:Tra1Imported
ORF Names:mCG_8346Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98817. Hsp90b1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500842437922 – 802Sequence analysisAdd BLAST781

Proteomic databases

TopDownProteomicsiQ3UAD6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020048.
ExpressionAtlasiQ3UAD6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020238.

Structurei

3D structure databases

SMRiQ3UAD6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 255HATPase_cInterPro annotationAdd BLAST160

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili296 – 318Sequence analysisAdd BLAST23

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0020. Eukaryota.
COG0326. LUCA.
HOVERGENiHBG007374.
KOiK09487.
OMAiRKPADVT.
OrthoDBiEOG091G0270.

Family and domain databases

Gene3Di3.30.565.10. 2 hits.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF02518. HATPase_c. 1 hit.
PF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 2 hits.
PROSITEiPS00298. HSP90. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UAD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLWVLGLC CVLLTFGFVR ADDEVDVDGT VEEDLGKSRE GSRTDDEVVQ
60 70 80 90 100
REEEAIQLDG LNASQIRELR EKSEKFAFQA EVNRMMKLII NSLYKNKEIF
110 120 130 140 150
LRELISNASD ALDKIRLISL TDENALAGNE ELTVKIKCDK EKNLLHVTDT
160 170 180 190 200
GVGMTREELV KNLGTIAKSG TSEFLNKMTE AQEDGQSTSE LIGQFGVGFY
210 220 230 240 250
SAFLVADKVI VTSKHNNDTQ HIWESDSNEF SVIADPRGNT LGRGTTITLV
260 270 280 290 300
LKEEASDYLE LDTIKNLVRK YSQFINFPIY VWSSKTETVE EPLEEDEAAK
310 320 330 340 350
EEKEESDDEA AVEEEEEEKK PKTKKVEKTV WDWELMNDIK PIWQRPSKEV
360 370 380 390 400
EEDEYKAFYK SFSKESDDPM AYIHFTAEGE VTFKSILFVP TSAPRGLFDE
410 420 430 440 450
YGSKKSDYIK LYVRRVFITD DFHDMMPKYL NFVKGVVDSD DLPLNVSRET
460 470 480 490 500
LQQHKLLKVI RKKLVRKTLD MIKKIADEKY NDTFWKEFGT NIKLGVIEDH
510 520 530 540 550
SNRTRLAKLL RFQSSHHSTD ITSLDQYVER MKEKQDKIYF MAGSSRKEAE
560 570 580 590 600
SSPFVERLLK KGYEVIYLTE PVDEYCIQAL PEFDGKRFQN VAKEGVKFDE
610 620 630 640 650
SEKTKESREA TEKEFEPLLN WMKDKALKDK IEKAVVSQRL TESPCALVAS
660 670 680 690 700
QYGWSGNMER IMKAQAYQTG KDISTNYYAS QKKTFEINPR HPLIRDMLRR
710 720 730 740 750
IKEDEDDKTV MDLAVVLFET ATLRSGYLLP DTKAYGDRIE RMLRLSLNID
760 770 780 790 800
PEAQVEEEPE EEPEDTSEDA EDSEQDEGEE MDAGTEEEEE ETEKESTEKD

EL
Length:802
Mass (Da):92,476
Last modified:October 11, 2005 - v1
Checksum:iBDF33B9BD86BFC5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146885 mRNA. Translation: BAE27505.1.
AK151413 mRNA. Translation: BAE30378.1.
AK153550 mRNA. Translation: BAE32087.1.
AK159974 mRNA. Translation: BAE35526.1.
AK165975 mRNA. Translation: BAE38494.1.
AK168952 mRNA. Translation: BAE40758.1.
AK169090 mRNA. Translation: BAE40874.1.
CH466539 Genomic DNA. Translation: EDL21440.1.
RefSeqiNP_035761.1. NM_011631.1.
UniGeneiMm.87773.

Genome annotation databases

GeneIDi22027.
KEGGimmu:22027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146885 mRNA. Translation: BAE27505.1.
AK151413 mRNA. Translation: BAE30378.1.
AK153550 mRNA. Translation: BAE32087.1.
AK159974 mRNA. Translation: BAE35526.1.
AK165975 mRNA. Translation: BAE38494.1.
AK168952 mRNA. Translation: BAE40758.1.
AK169090 mRNA. Translation: BAE40874.1.
CH466539 Genomic DNA. Translation: EDL21440.1.
RefSeqiNP_035761.1. NM_011631.1.
UniGeneiMm.87773.

3D structure databases

SMRiQ3UAD6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020238.

Proteomic databases

TopDownProteomicsiQ3UAD6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22027.
KEGGimmu:22027.

Organism-specific databases

CTDi7184.
MGIiMGI:98817. Hsp90b1.

Phylogenomic databases

eggNOGiKOG0020. Eukaryota.
COG0326. LUCA.
HOVERGENiHBG007374.
KOiK09487.
OMAiRKPADVT.
OrthoDBiEOG091G0270.

Miscellaneous databases

ChiTaRSiHsp90b1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020048.
ExpressionAtlasiQ3UAD6. baseline and differential.

Family and domain databases

Gene3Di3.30.565.10. 2 hits.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF02518. HATPase_c. 1 hit.
PF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 2 hits.
PROSITEiPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UAD6_MOUSE
AccessioniPrimary (citable) accession number: Q3UAD6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 30, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.