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Q3U9B7

- Q3U9B7_MOUSE

UniProt

Q3U9B7 - Q3U9B7_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Ctsc

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chloride ion binding Source: Ensembl
    2. cysteine-type peptidase activity Source: UniProtKB-KW
    3. peptidase activator activity involved in apoptotic process Source: MGI

    GO - Biological processi

    1. aging Source: Ensembl
    2. apoptotic process Source: GOC
    3. positive regulation of apoptotic signaling pathway Source: MGI
    4. response to organic substance Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol proteaseSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:CtscImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:109553. Ctsc.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. Golgi apparatus Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ3U9B7.
    BgeeiQ3U9B7.
    GenevestigatoriQ3U9B7.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase C1 family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG005248.
    InParanoidiQ3U9B7.

    Family and domain databases

    Gene3Di2.40.128.80. 1 hit.
    InterProiIPR014882. CathepsinC_exc.
    IPR025661. Pept_asp_AS.
    IPR000169. Pept_cys_AS.
    IPR025660. Pept_his_AS.
    IPR013128. Peptidase_C1A.
    IPR000668. Peptidase_C1A_C.
    [Graphical view]
    PANTHERiPTHR12411. PTHR12411. 1 hit.
    PfamiPF08773. CathepsinC_exc. 1 hit.
    PF00112. Peptidase_C1. 1 hit.
    [Graphical view]
    PRINTSiPR00705. PAPAIN.
    SMARTiSM00645. Pept_C1. 1 hit.
    [Graphical view]
    SUPFAMiSSF75001. SSF75001. 1 hit.
    PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
    PS00139. THIOL_PROTEASE_CYS. 1 hit.
    PS00639. THIOL_PROTEASE_HIS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3U9B7-1 [UniParc]FASTAAdd to Basket

    « Hide

    LLGVCTVRSD TPANCTYPDL LGTWVFQVGP RSSRSDINCS VMEATEEKVV    50
    VHLKKLDTAY DELGNSGHFT LIYNQGFEIV LNDYKWFAFF KYEVRGHTAI 100
    SYCHETMTGW VHDVLGRNWA CFVGKKVESH IEKVNMNAAH LGGLQERYSE 150
    RLYTHNHNFV KAINTVQKSW TATAYKEYEK MSLRDLIRRS GHSQRIPRPK 200
    PAPMTDEIQQ QILNLPESWD WRNVQGVNYV SPVRNQESCG SCYSFASMGM 250
    LEARIRILTN NSQTPILSPQ EVVSCSPYAQ GCDGGFPYLI AGKYAQDFGV 300
    VEESCFPYTA KDSPCKPREN CLRYYSSDYY YVGGFYGGCN EALMKLELVK 350
    HGPMAVAFEV HDDFLHYHSG IYHHTGLSDP FNPFELTNHA VLLVGYGRDP 400
    VTGIEYWIIK NSWGSNWGES GYFRIRRGTD ECAIESIAVA AIPIPKL 447
    Length:447
    Mass (Da):50,701
    Last modified:October 11, 2005 - v1
    Checksum:iED40A52293C3EFED
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK151861 mRNA. Translation: BAE30750.1.
    UniGeneiMm.322945.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK151861 mRNA. Translation: BAE30750.1 .
    UniGenei Mm.322945.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:109553. Ctsc.

    Phylogenomic databases

    HOVERGENi HBG005248.
    InParanoidi Q3U9B7.

    Miscellaneous databases

    ChiTaRSi CTSC. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3U9B7.
    Bgeei Q3U9B7.
    Genevestigatori Q3U9B7.

    Family and domain databases

    Gene3Di 2.40.128.80. 1 hit.
    InterProi IPR014882. CathepsinC_exc.
    IPR025661. Pept_asp_AS.
    IPR000169. Pept_cys_AS.
    IPR025660. Pept_his_AS.
    IPR013128. Peptidase_C1A.
    IPR000668. Peptidase_C1A_C.
    [Graphical view ]
    PANTHERi PTHR12411. PTHR12411. 1 hit.
    Pfami PF08773. CathepsinC_exc. 1 hit.
    PF00112. Peptidase_C1. 1 hit.
    [Graphical view ]
    PRINTSi PR00705. PAPAIN.
    SMARTi SM00645. Pept_C1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF75001. SSF75001. 1 hit.
    PROSITEi PS00640. THIOL_PROTEASE_ASN. 1 hit.
    PS00139. THIOL_PROTEASE_CYS. 1 hit.
    PS00639. THIOL_PROTEASE_HIS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.

    Entry informationi

    Entry nameiQ3U9B7_MOUSE
    AccessioniPrimary (citable) accession number: Q3U9B7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)