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Protein
Submitted name:

CD44 antigen

Gene

Cd44

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1474228. Degradation of the extracellular matrix.
R-MMU-202733. Cell surface interactions at the vascular wall.
R-MMU-216083. Integrin cell surface interactions.
R-MMU-2160916. Hyaluronan uptake and degradation.
R-MMU-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 antigenImported
Gene namesi
Name:Cd44Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:88338. Cd44.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei273 – 294HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501120935621 – 365Sequence analysisAdd BLAST345

Expressioni

Gene expression databases

BgeeiENSMUSG00000005087.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 125LinkInterPro annotationAdd BLAST90

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.
HOVERGENiHBG003850.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR016186. C-type_lectin-like/link_sf.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
PANTHERiPTHR10225:SF6. PTHR10225:SF6. 2 hits.
PfamiView protein in Pfam
PF00193. Xlink. 1 hit.
PRINTSiPR00658. CD44.
PR01265. LINKMODULE.
SMARTiView protein in SMART
SM00445. LINK. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS01241. LINK_1. 1 hit.
PS50963. LINK_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3U8S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKFWWHTAW GLCLLQLSLA HPHQQIDLNV TCRYAGVFHV EKNGRYSISR
60 70 80 90 100
TEAADLCQAF NSTLPTMDQM KLALSKGFET CRYGFIEGNV VIPRIHPNAI
110 120 130 140 150
CAANHTGVYI LVTSNTSHYD TYCFNASAPP EEDCTSVTDL PNSFDGPVTI
160 170 180 190 200
TIVNRDGTRY SKKGEYRTHQ EDIDASNIID DDVSSGSTIE KSTPESYILH
210 220 230 240 250
TYLPTEQPTG DQDDSFFIRS TLATRDRDSS KDSRGSSRTV THGSELAGHS
260 270 280 290 300
SANQDSGVTT TSGPMRRPQI PEWLIILASL LALALILAVC IAVNSRRRCG
310 320 330 340 350
QKKKLVINGG NGTVEDRKPS ELNGEASKSQ EMVHLVNKEP SETPDQCMTA
360
DETRNLQSVD MKIGV
Length:365
Mass (Da):40,263
Last modified:October 11, 2005 - v1
Checksum:iD03B13FCE355B7BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844155 Genomic DNA. No translation available.
AK152099 mRNA. Translation: BAE30946.1.
RefSeqiNP_001034240.1. NM_001039151.1.
UniGeneiMm.423621.

Genome annotation databases

EnsembliENSMUST00000099673; ENSMUSP00000097265; ENSMUSG00000005087.
GeneIDi12505.
UCSCiuc008lig.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ3U8S1_MOUSE
AccessioniPrimary (citable) accession number: Q3U8S1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 22, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported