Q3U8J8 (Q3U8J8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAE31020.1

Gene names

Name:

Il6 MGI 96559

Organism

Mus musculus (Mouse) EMBL BAE31020.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	immune response Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	cytokine activity Inferred from electronic annotation. Source: InterPro interleukin-6 receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3U8J8 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 5EA92D00E9134EDC	FASTA	194	22,493
	10 20 30 40 50 60 MLVTTTAFPT SQVRRGDFTE DTTHNRPVYT TSQVGGLITH VLWEIVEMRK ELCNGNSDCM 70 80 90 100 110 120 NNDDALAENN LKLPEIQRND GCYQTGYNQE ICLLKISSGL LEYHSYLEYM KNNLKDNKKD 130 140 150 160 170 180 KARVLQRDTE TLIHIFNQEV KDLHKIVLPT PISNALLTDK LESQKEWLRT KTIQFILKSL 190 EEFLKVTLRS TRQT

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed: 10349636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[2]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed: 16141073] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[3]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[4]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[6]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed: 11042159] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[7]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed: 11076861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.
[8]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE31020.1. Tissue: Bone marrow EMBL BAE31020.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK152189 mRNA. Translation: BAE31020.1.
IPI	IPI00133702.
UniGene	Mm.1019.
3D structure databases
ProteinModelPortal	Q3U8J8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3U8J8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
GeneTree	ENSGT00390000000878.
HOVERGEN	HBG000471.
InParanoid	Q3U8J8.
Gene expression databases
ArrayExpress	Q3U8J8.
Genevestigator	Q3U8J8.
Family and domain databases
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR012351. 4_helix_cytokine_core. IPR003573. IL6_MGF_GCSF. IPR003574. Interleukin_6. [Graphical view]
Gene3D	G3DSA:1.20.1250.10. 4_helix_cytokine_core. 1 hit.
PANTHER	PTHR11457. Interleukin_6. 1 hit.
Pfam	PF00489. IL6. 1 hit. [Graphical view]
PIRSF	PIRSF001935. IL6_MGF_GCSF. 1 hit.
PRINTS	PR00433. IL6GCSFMGF. PR00434. INTERLEUKIN6.
SMART	SM00126. IL6. 1 hit. [Graphical view]
SUPFAM	SSF47266. 4_helix_cytokine. 1 hit.
PROSITE	PS00254. INTERLEUKIN_6. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3U8J8_MOUSE

Accession

Primary (citable) accession number: Q3U8J8

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	October 19, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)