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Unreviewed, UniProtKB/TrEMBL Q3U879 (Q3U879_MOUSE)

Last modified January 19, 2010. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Putative uncharacterized protein EMBL BAE31139.1
Gene names
Name: Il10 MGI 96537
OrganismMus musculus (Mouse) EMBL BAE31139.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length178 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processbranching involved in embryonic placenta morphogenesis

Inferred from mutant phenotype. Source: MGI

defense response to bacterium

Inferred from direct assay. Source: MGI

immune response

Inferred from electronic annotation. Source: InterPro

negative regulation of B cell proliferation

Inferred from electronic annotation. Source: Compara

negative regulation of cytokine secretion during immune response

Inferred from electronic annotation. Source: Compara

negative regulation of inflammatory response

Inferred from electronic annotation. Source: Compara

negative regulation of interleukin-12 production

Inferred from mutant phenotype. Source: MGI

negative regulation of interleukin-6 production

Inferred from electronic annotation. Source: Compara

negative regulation of membrane protein ectodomain proteolysis

Inferred from electronic annotation. Source: Compara

negative regulation of myeloid dendritic cell activation

Inferred from mutant phenotype. Source: MGI

negative regulation of nitric oxide biosynthetic process

Inferred from electronic annotation. Source: Compara

negative regulation of tumor necrosis factor biosynthetic process

Inferred from electronic annotation. Source: Compara

positive regulation of B cell apoptosis

Inferred from electronic annotation. Source: Compara

positive regulation of MHC class II biosynthetic process

Inferred from direct assay. Source: MGI

positive regulation of cytokine secretion

Inferred from electronic annotation. Source: Compara

positive regulation of gene-specific transcription

Inferred from electronic annotation. Source: Compara

positive regulation of transcription factor activity

Inferred from electronic annotation. Source: Compara

receptor biosynthetic process

Inferred from electronic annotation. Source: Compara

regulation of sensory perception of pain

Inferred from electronic annotation. Source: Compara

response to glucocorticoid stimulus

Inferred from electronic annotation. Source: Compara

response to insulin stimulus

Inferred from electronic annotation. Source: Compara

response to lipopolysaccharide

Inferred from electronic annotation. Source: Compara

   Cellular componentextracellular space

Inferred from direct assay. Source: MGI

   Molecular functioncytokine activity

Inferred from direct assay. Source: MGI

interleukin-10 receptor binding

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
Q3U879-1 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 9A35E3AFE144F12B

FASTA17820,671
        10         20         30         40         50         60 
MPGSALLCCL LLLTGMRISR GQYSREDNNC THFPVGQSHM LLELRTAFSQ VKTFFQTKDQ 

        70         80         90        100        110        120 
LDNILLTDSL MQDFKGYLGC QALSEMIQFY LVEVMPQAEK HGPEIKEHLN SLSEKLKTLR 

       130        140        150        160        170 
MRLRRCHRFL PCENKSKAVE QVKSDFNKLQ DQGVYKAMNE FDIFINCIEA YMMIKMKS

« Hide

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References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J EMBL BAE31139.1.
Tissue: Bone marrow EMBL BAE31139.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK152344 mRNA. Translation: BAE31139.1.
IPIIPI00654087.
UniGeneMm.874

3D structure databases

SMRQ3U879. Positions 24-178.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3U879.

Genome annotation databases

EnsemblENSMUST00000016673; ENSMUSP00000016673; ENSMUSG00000016529; Mus musculus. [Genome view]

Organism-specific databases

MGIMGI:96537. Il10.

Phylogenomic databases

HOVERGENQ3U879.
InParanoidQ3U879.

Gene expression databases

ArrayExpressQ3U879.
BgeeQ3U879.
GenevestigatorQ3U879.

Family and domain databases

InterProIPR009079. 4_helix_cytokine-like_core.
IPR012352. IL-10_add_helix.
IPR020443. Interleukin-10/19/20/24.
IPR020423. Interleukin-10_CS.
IPR000098. Interleukin_10.
[Graphical view]
Gene3DG3DSA:4.10.340.10. IL-10_add_helix. 1 hit.
PANTHERPTHR11585. Interleukin_10. 1 hit.
PfamPF00726. IL10. 1 hit.
[Graphical view]
PRINTSPR01294. INTRLEUKIN10.
SMARTSM00188. IL10. 1 hit.
[Graphical view]
PROSITEPS00520. INTERLEUKIN_10. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

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Entry information

Entry nameQ3U879_MOUSE
AccessionPrimary (citable) accession number: Q3U879
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: January 19, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information